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59 articles for “Antibiotic Resistant”

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Research ArticleOpen accessIn the abstractImpact of Antimicrobial Stewardship Programme on Carbapenem Resistance in Gram Negative Isolates in an Indian Tertiary Care HospitalNamita Jaggi, Pushpa Sissodia, Lalit SharmaProblem statement: Increasing Antimicrobial resistance in the World is constantly becoming a Global threat and there is an urgent need to prevent its spread. Various studies of last decade have shown reduced trends of antimicrobial resistance in the pathogens as an outcome of the Antimicrobial Stewardship Programs. In view of this, the present four years’ study was carried out to … …American Journal of Infectious Diseases, Vol. 8, Issue 2 · 2 Oct 2012 · 7,627 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn Vitro Activity of Tigecycline in the Era of NDM-1Dorairajan Sureshkumar, Ram Gopalakrishnan, M.A. ThirunarayanIn the current era of New Delhi Metallo-betalactamase-1 (NDM-1) infections and a dry antibiotic pipeline, managing infections caused by Multi-Drug Resistant Gram-Negative Bacterial infections (MDR-GNBs) presents a great challenge to physicians in the developing world. Tigecycline, a broad spectrum glycylcycline is a one among the few treatment options against MDR-GNBs. However it has been studied mostly in the western world, … …Current Research in Microbiology, Vol. 3, Issue 2 · 12 Sep 2012 · 7,497 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntibiotic Resistance and Chromium Reduction Pattern Among ActinomycetesPreeti Jain, Alina Amatullah, Samiul Alam Rajib, Hasan Mahmud RezaActinomycetes, one of the most important groups of microbes, exhibit many interesting activities such as degradation and transformation of organic and metal substrates together with production of antibiotics. With these bioactivities, actinomycetes would play an important role in the webs of the marine environment. The present study was designed to evaluate the antibiotic resistance pattern, antibiotic producing potential and chromium … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 2 · 22 Jun 2012 · 8,908 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntibiotic Sensitivity Pattern of Blood Isolates of Acinetobacter Species in a Tertiary Care Hospital: A Retrospective AnalysisP. S. Shareek, D. Sureshkumar, Ramgopalakrishnan et al.Problem statement: Multi-drug resistant Acinetobacter bacterium is one of the major causes of sepsis in ICUs in tertiary care hospitals in India. In this report we describe the antibiotic sensitivity patterns of Acinetobacter species isolated from blood over a one year period at a tertiary care hospital. Approach: We retrospectively analyzed the sensitivity pattern of Acinetobacter species isolated from blood … …American Journal of Infectious Diseases, Vol. 8, Issue 1 · 24 Mar 2012 · 8,570 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntibiotic Compounds from Bacillus: Why are they so Amazing?Patrick FickersThe constant increase of multi-drug resistant pathogens stimulates research, more than ever, to identify and develop new antibacterial compounds. The recent advances in genome sequencing have highlighted the genus Bacillus as an unexpected source of antibiotic-like compounds. This review focus on the different class of antimicrobial molecules produce by Bacillus genus such as polyketides, nonribosomal peptide, bacteriocins as well as … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 1 · 15 Mar 2012 · 9,689 accessesView PDFCite
Research ArticleOpen accessIn the abstractUse of Enterobacterial Repetitive Intergenic Consensus PCR in Detecting Target(s) of Hapalindole-T, From a Cyanobacterium, in Escherichia Coli: In Silico ValidationManoj K. Tripathi, Maheep Kumar, Vinay K. Singh et al.Problem statement: Identification of newer biomolecule as well as targets are a rising concern because of increasing drug resistance in bacteria. We have isolated a broad spectrum antibiotic biomolecule Hapalindole-T from a cyanobacterium, Fisherella sp. growing on local Azadirachta indica tree bark. A model bacterium E. coli was screened spontaneously for Hap-T resistance. These resistant strains of E. coli were … …Current Research in Bioinformatics, Vol. 1, Issue 1 · 3 Mar 2012 · 13,780 accessesView PDFCite
Research ArticleOpen accessIn the abstractCharacterization of Escherichia coli Isolates from Commercial Layer Hens with SalpingitisMahmood Salehi, Reza GhanbarpourProblem statement: Escherichia coli isolates are the most common bacterial agents of salpingitis in commercial layer hens. The objectives of this study were to determine the phylogenetic groups/subgroups and antibiotic resistance of E. coli isolates from salpingitis cases in commercial layer hens farms in southeast of Iran. Approach: One hundred twenty one E. coli isolates from oviducts of layer hens … …American Journal of Animal and Veterinary Sciences, Vol. 5, Issue 3 · 30 Sep 2010 · 8,955 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntibacterial Activity of Marine Source Extracts Against Multidrug Resistance OrganismsNagi A. AL-Haj, Nurmas I. Mashan, Mariana N. Shamsudin et al.Problem statement: Antimicrobial resistance is the major problem of global dimensions with a significant impact on morbidity, mortality and healthcare-associated costs. The problem has recently been worsened by the steady increase in multiresistant strains and by the restriction of antibiotic discovery and development programs. Methicillin-resistant Staphylococcus aureus, pseudomonads and Escherichia coli are a major nosocomial and community-acquired pathogens for which … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 2 · 30 Jun 2010 · 10,078 accessesView PDFCite
Research ArticleOpen accessIn the abstractScreening of Actinomycete Isolates from Niche Habitats in Manipur for Antibiotic ActivityDebananda S. Ningthoujam, Suchitra Sanasam, Salam NimaichandProblem statement: The exhaustion of the usual terrestrial sources and the rise of resistant pathogens dictate the search for novel actinomycetes and new antibiotics. In this context, niche habitats such as caves, pristine forests, lakes, rivers, and other wetlands, high salt environments, marine ecosystems and endophytic niches are promising targets for survey of bioactive actinomycetes. Approach: Actinomycetes were isolated from … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 4 · 31 Dec 2009 · 7,772 accessesView PDFCite
Research ArticleOpen accessIn the abstractIdentification of Clonal Clusters of Klebsiella pneumoniae Isolates from Chennai by Extended Spectrum Beta Lactamase Genotyping and Antibiotic Resistance Phenotyping AnalysisC. Kamatchi, H. Magesh, Uma Sekhar, Rama VaidyanathanProblem statement: An increased resistance to antibiotics has been reported in Klebsiella pneumoniae, an opportunistic gram negative pathogen belonging to Entrobacteraceae due to the evolution and spread of plasmid encoded extended spectrum beta lactamases and other genes conferring cross-resistance to other antibiotics. This is of concern due to the increasing cost of antibiotic treatment and the spread of multidrug resistance … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 7,958 accessesView PDFCite