44 results for “Animal Models”

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Research ArticleOpen accessIn the abstractBridging from Cells to Cognition in Autism Pathophysiology: Biological Pathways to Defective Brain Function and PlasticityMatthew P. Anderson, Brian S. Hooker, Martha R. HerbertWe review evidence to support a model where the disease process underlying autism may begin when an in utero or early postnatal environmental, infectious, seizure, or autoimmune insult triggers an immune response that increases reactive oxygen species (ROS) production in the brain that leads to DNA damage (nuclear and mitochondrial) and metabolic enzyme blockade and that these inflammatory and oxidative … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 17,455 accessesView PDF Cite

Research ArticleOpen accessIn the abstractNeuropsychological Consequences of HIV and Drug AuseArun Venkatesan, Ola Selnes, Valerie Wojna et al.Accurate assessment of the functional consequences of human immunodeficiency virus (HIV) infection and drugs of abuse are critical as large populations are afflicted with both. Both are interdependent epidemics with important socioeconomic consequences. Experimental studies in animal models and in vitro clearly indicate that HIV and drugs of abuse cause increased neurodegeneration, glial cell activation and enhanced HIV replication. Nevertheless, … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 6,662 accessesView PDF Cite

Research ArticleOpen accessIn the abstractIn vitro Effects of Beet Root Juice on Stimulated and Unstimulated Peripheral Blood Mononuclear CellsChristiana Winkler, Barbara Wirleitner, Katharina Schroecksnadel et al.Intake of fruits and vegetables rich in antioxidants is suggested to reduce the incidence of cancer and coronary heart disease in humans. Exceptional antioxidant activity of beet root extracts has been reported. Likewise in animal models, e.g., extracts of red beetroot Beta vulgaris var. rubra revealed significant tumor inhibitory effects. Red beetroot concentrate is universally permitted as a food ingredient. … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 4 · 31 Dec 2005 · 9,522 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordModulation of IFN-γ, IL-4 and IL-17 Cytokines is Related to Parasitemia Control in Mice Infected by Trypanosoma cruzi and Treated with BiotherapyFabiana Nabarro Ferraz, Franciele Karina da Veiga, Denise Lessa Aleixo et al.The study of biotherapies as an intervention in experimental models of infection is a possible means to understand the effects of these highly diluted medications. The present study evaluated the immunological and parasitological effects of biotherapies that were prepared from mouse serum that was uninfected (sarcode: BSNI13cH group) and chronically infected with the Y strain of T. cruzi (nosode: BSI13cH … …OnLine Journal of Biological Sciences, Vol. 15, Issue 4 · 30 Oct 2015 · 7,357 accessesView PDF Cite