489 articles for “significantly different”

Research ArticleOpen accessIn the abstractAntibacterial Activity of β-Cyclodextrin and 2-Hydroxypropyl-β-Cyclodextrin Trimethoprim ComplexesHsien-Kuo Sun, Madhumathi Seshadri, Scott Lingard et al.Problem statement: Cyclodextrin complexation has previously been shown to improve the solubility and dissolution properties of trimethoprim; however, no report provides an account of the effect cyclodextrin complexation has on the antibacterial activity of this agent. Approach: β-cyclodextrin and 2-hydroxypropyl β-cyclodextrin inclusion complexes of trimethoprim were prepared and confirmed by differential scanning calorimetry and proton nuclear magnetic resonance. The in-vitro … …Current Research in Microbiology, Vol. 2, Issue 1 · 26 Oct 2011 · 14,806 accessesView PDF Cite

Research ArticleOpen accessIn the abstractProduction and Roles of Glial Tissue Inhibitor of Metalloproteinases-1 in Human Immunodeficiency Virus-1-Associated Dementia Neuroinflammation: A ReviewC. Chao, A. GhorpadeProblem statement: Tissue Inhibitor of Metalloproteinases-1 (TIMP-1) and its cognate targets, the Matrix Metalloproteinases (MMPs), were differentially expressed in human brain samples with or without HIV-1 infection or HIV-1 Encephalitis (HIVE). Approach: A through literature review demonstrated that cell culture models of Central Nervous System (CNS) cell types had been used to illustrate the intricate temporal patterns of TIMP-1/MMP expression, … …American Journal of Infectious Diseases, Vol. 5, Issue 4 · 31 Dec 2009 · 6,957 accessesView PDF Cite

Research ArticleOpen accessIn the abstractEvaluation of the Activity of Plant Extracts in Boer GoatsM. Worku, R. Franco, J. H. MillerProblem statement: The effect of extracts from Neem (Azadirachta indica), Wormwood (Artemisia absinthium) and Tobacco (Nicotiana tabacum) with added copper sulfate, on female Boer goats infected with gastrointestinal parasites (GIN) was evaluated. Approach: Following initial screening for infection, animals were artificially infected with a mix containing approximately 80% Haemonchus contortus and 20% Trichostrongylus spp. After 21 days, fecal samples were … …American Journal of Animal and Veterinary Sciences, Vol. 4, Issue 4 · 21 Dec 2009 · 8,477 accessesView PDF Cite

Research ArticleOpen accessIn the abstractHot Machining of Hardened Steels with Coated Carbide InsertsM. A. Lajis, A. K.M.N. Amin, A. N.M. Karim et al.Problem statement: The benefits of easier manufacture of hardened steel components can be substantial in terms of reduced machining costs and lead times compared to the traditional route involving machining of the annealed state followed by heat treatment, grinding/EDM and manual finishing. But machinability of hard material through conventional machining is hindered due to excessive wear of the cutting tools … …American Journal of Engineering and Applied Sciences, Vol. 2, Issue 2 · 30 Jun 2009 · 8,384 accessesView PDF Cite

Research ArticleOpen accessIn the abstractA Light-Weight Service Discovery Protocol for Ad Hoc NetworksRanwa Al Mallah, Alejandro QuinteroProblem statement: In mobile ad hoc networks devices do not rely on a fixed infrastructure and thus have to be self-organizing. This gives rise to various challenges to network applications. Existing service discovery protocols fall short of accommodating the complexities of the ad-hoc environment. However, the performance of distributed service discovery architectures that rely on a virtual backbone for locating … …Journal of Computer Science, Vol. 5, Issue 4 · 30 Apr 2009 · 7,343 accessesView PDF Cite

Research ArticleOpen accessIn the abstractPeripheral Blood Leukocyte Production of BDNF following Mitogen Stimulation in Early Onset and Regressive AutismAmanda Enstrom, Charity Onore, Angela Tarver et al.Brain-derived neurotrophic factor (BDNF) is critical for neuronal differentiation and synaptic development. BDNF is also implicated in the development of psychological disorders including depression, bipolar disorder and schizophrenia. Previously, elevated BDNF levels were observed in neonatal blood samples from infants who were later diagnosed with autism when compared with children who developed normally, suggesting that BDNF may be involved in … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 8,528 accessesView PDF Cite

Research ArticleOpen accessIn the abstractRedox Sensing and Cardiac Myocyte Loss: Some Recent InsightsShyamal K. GoswamiGeneration of reactive oxygen-nitrogen species (ROS/RNS) has long been ascribed to pathophysiological conditions like ageing, neurodegenerative and cardiovascular disorders. However, more recent evidences suggest that while generation of ROS/RNS at a higher threshold is deleterious, at a lower dose these can act as second messengers, influencing specific cellular events like cell growth and differentiation, embryonic development, protection against ischemic injuries … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 4 · 31 Dec 2007 · 6,350 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordAlterations of HDL Subclasses in Different Lipid Levels of Men and WomenYuye Yang, Luchuan Yang, Mingde Fu et al.With the increase of plasma TG level, both in men and women, apoA-I concentrations of preβ1-HDL and HDL3a were significantly higher while HDL2a and HDL2b were significantly lower. Similarly, with the increase of plasma LDL-C level, apoA-Iconcentrations of preβ1-HDL, HDL3c(in men) and HDL3b were significantly higher while apoA-Iconcentrations of HDL2b were significantly lower. And with the decrease of plasma HDL-C, … …American Journal of Immunology, Vol. 1, Issue 2 · 30 Jun 2005 · 9,077 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordEffect of Different Exogeneous Compounds on Biosorption of EndosulfanDeepika Dave, A. K. DikshitProblem statement: Organochlorine pesticide endosulfan is widely used as a replacement for DDT and dieldrin in many parts of the world. Presence of residual pesticides in the water, air and soil environment was confirmed since 1960s. Such Persistent Organic Pollutants (POPs) are of concern because of their long-term subtle effects on hormones, the immune system and reproduction. Therefore, it becomes … …American Journal of Environmental Sciences, Vol. 7, Issue 3 · 11 Jul 2011 · 7,205 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordTotal Level of Serum Homocysteine in Males and Females with Coronary Heart Disease of Different Age GroupsFaisal I. Mohammad, Sally Awawdeh, Akram Saleh, Nabil A. BashirProblem statement: Elevated plasma total homocysteine concentration is a risk factor of cardiovascular disease. Total homocysteine level is a strong predictor of mortality in-patient with an angiographically confirmed Coronary Heart Disease (CHD), so we want to know at what age in males and females elevated homocysteine will be significantly elevated and this will help for better management and prognosis by … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 2 · 30 Jun 2010 · 7,542 accessesView PDF Cite