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497 results for “N. Amin”
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Research ArticleOpen accessIn the abstractIntrinsically Unstructured Proteins: Potential Targets for Drug DiscoveryPathan Salma, Chintan Chhatbar, Sriram SeshadriProblem statement: The function of a protein is dependent on its three-dimensional structure. However, numerous proteins lacking intrinsic globular 3D structure under physiological conditions had been recognized. These proteins are frequently involved in some of the most critical cellular control mechanisms and it appears that their rapid turnover, aided by their unstructured nature in the unbound state, provides a level … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 7,579 accessesView PDFCite
Research ArticleOpen accessIn the abstractCharacterization of the Adsorption of the Lead (II) by the Nonliving Biomass Spirogyra neglecta (Hasall) KutzingModher A. Hussain, Aishah Salleh, Pozi MilowProblem statement: Conventional techniques for removing dissolved heavy metals are only practical and cost-effective when applied to high strength wastes with heavy metal ion concentrations greater than 100 ppm. The possibility of using a nonliving algal biomass to solve this problem was carried in this study. Lead (II) was used in this study because it had been reported to cause … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 2 · 30 Jun 2009 · 7,810 accessesView PDFCite
Research ArticleOpen accessIn the abstractWhat these Trends Suggest?Shaomin Yan, Guang WuProblem statement: Global warming is one of most significant factors affecting the biological evolution and the influenza is the disease that threatens humans with possible epidemics or pandemics. It would be important to understand if the global warming would have potential impact on the evolution of influenza virus. For this aim, the first would be to study the trend of … …American Journal of Applied Sciences, Vol. 6, Issue 6 · 30 Jun 2009 · 6,886 accessesView PDFCite
Research ArticleOpen accessIn the abstractResistance to Third-Generation Cephalosporins and Other Antibiotics by Enterobacteriaceae in Western NigeriaA. O. Okesola, O. MakanjuolaProblem statement: The emergence and spread of resistance to third-generation cephalosporins are threatening to create species resistant to all currently available agents. The most common cause of bacterial resistance to beta-lactam antibiotics is the production of beta-lactamases and many of the 2nd and 3rd-generation penicillins and cephalosporins were specifically designed to resist the hydrolytic action of major β-lactamases. However new … …American Journal of Infectious Diseases, Vol. 5, Issue 1 · 31 Mar 2009 · 8,012 accessesView PDFCite
Research ArticleOpen accessIn the abstractImproving Protein 3D Structure Prediction Accuracy using Dense Regions Areas of Secondary Structures in the Contact MapAmer F. Al-Badarneh, Mohammad A. Khalil, Mo'taz A. Al-HamiProblem Statement: The protein folding problem is a fundamental problem in structural molecular biology. This problem describes how a protein is transformed from its primary sequence (i.e., amino acid sequence) into the three dimensional structure (3D structure) for this sequence that determines the function of the protein. The 3D structure of a protein can be represented using a square symmetrical … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 4 · 31 Dec 2008 · 7,537 accessesView PDFCite
Research ArticleOpen accessIn the abstractHydrophobic, Polar and Hydrogen Bonding Based Drug-Receptor Interaction of TetrahydroimidazobenzodiazepinonesV.K. Sahu, A.K.R. Khan, R.K. Singh, P.P. SinghAnti-HIV drug discovery has been increasingly focusing on HIV-1-RT (reverse transcriptase) as a potential therapeutic target. Tetrahydroimidazobenzodiazepinone (TIBO) belongs to non-nucleoside group of reverse transcriptase inhibitors (NNRTIs). A computational chemistry study has been performed on a series of tetrahydroimidazo-benzodiazepinones as HIV-1-NNRT inhibitors. Problem statement: In order to search out new drug of desired activity from the lead compounds, there was … …American Journal of Immunology, Vol. 4, Issue 3 · 30 Sep 2008 · 8,839 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of pollution on lead and cadmium concentration and correlation with biochemical parameters in blood of human population nearby Kosovo thermo power plantsEugene Oks, N.M. Daci, M.N. Daci-Ajvazi, H. PaçariziThis study describes an investigation of lead and cadmium pollution of Kosovo environment as a result of outflow from the coal processing industry. In a comparative study of lead and cadmium concentration in blood of human population of two different environments in Kosovo, one nearby Kosovo Thermo Power Plants, (Obiliq) a highly polluted environment and the other that is considered … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 3 · 30 Sep 2008 · 7,196 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Frequency of Polymorphisms affecting Lead and Mercury Toxicity among Children with AutismShannon Rose, Stepan Melnyk, Alena Savenka et al.Individual risk of developmental neurotoxicity with exposure to environmentally relevant levels of lead and mercury is likely to be determined by genetic susceptibility factors as well as additive interactions with other environmental pollutants, cumulative dose, and the developmental stage of exposure. The apparent increase in autism diagnosis over the last 15 years has enhanced interest in the possibility that an … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 7,524 accessesView PDFCite
Research ArticleOpen accessIn the abstractC-Terminal Region of Dengue Virus Nonstructural Protein 1 Is Involved in Endothelial Cell Cross-Reactivity via Molecular MimicryShu-Wen Wan, Chiou-Feng Lin, Mei-Chun Chen et al.Infection with dengue virus (DV) causes diseases ranging from self-limited dengue fever to life-threatening dengue hemorrhagic fever and dengue shock syndrome. Vascular leakage, thrombocytopenia and bleeding are the clinical manifestations associated with dengue hemorrhage. We previously showed that anti-DV nonstructural protein 1 (NS1) antibodies (Abs) cross-reacted with endothelial cells. The potential target proteins on endothelial cell surface recognized by anti-DV … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,564 accessesView PDFCite
Research ArticleOpen accessIn the abstractCellular and Some Biochemical Changes in Blood and Peritoneal Fluid Constituents in Awassi Lambs Following Elective CastrationMohammad B.F. AL-Zghoul, Raida K. AL-Rukibat, Abdelsalam Q. Talafha et al.No reports could be cited in the recent literature concerning the effects of surgical castration on blood and peritoneal fluid constituents in lambs. The purpose of this study was to evaluate the effects of surgical castration on cellular and some biochemical parameters of blood and peritoneal fluid in Awassi lambs. Eight, clinically healthy, 5-month-old, Awassi lambs were surgically castrated. Peritoneal … …American Journal of Animal and Veterinary Sciences, Vol. 3, Issue 1 · 31 Mar 2008 · 7,244 accessesView PDFCite