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Research ArticleOpen accessIn the abstractEvaluation of Anti-Inflammatory Potential of Turmimax® an in vivo and in vitro StudyFiroz Hussain H M., Nanjundaiah S., Sadashiva Channangihalli Thimmegowda et al.The main objective of this study was to investigate the in vivo and in vitro anti-inflammatory effects of the Turmimax® bio-enhanced turmeric formulation. By comparing the relative fluorescence intensities of the interleukins IL-8 (Interleukin-8) and IL-12 (Interleukin-12) cytokines in stimulated murine Raw 264.7 macrophages, Turmimax® was evaluated for its anti-inflammatory in vitro efficacy. Turmimax® was administered orally in two doses, … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 4 · 24 Nov 2022 · 6,587 accessesView PDFCite
Research ArticleOpen accessIn the abstractSelective Susceptibility of Human Bladder Transitional Cell Carcinoma T24 Cells towards NBD PeptideSankari Durairajan, Charles Emmanuel Jebaraj Walter, Kalaiselvi Periyandavan et al.Bladder cancer is a recurrent disease that often develops chemoresistance and is on the rise in developing countries. After diagnosis surgery followed by immunotherapy and/or chemo- radiation therapy are the available treatments. These treatments do not provide protection against disease progression or recurrence thus highlighting the need to identify and develop drugs that are capable of inhibiting bladder cancer. T24 … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 20 Apr 2020 · 7,789 accessesView PDFCite
Research ArticleOpen accessIn the abstractDoes Iron Modulate Cytokine Production by Desferrioxamine Treated Mononuclear Cells?Hanna Bessler, Meir DjaldettiIron is an essential element for maintaining the normal function of cellular and multicellular organisms and it is closely associated with inflammation and immunity. Macrophages and lymphocytes play an important role in its homeostasis. Hereby we have evaluated cytokine production by iron depleted and iron supplemented human peripheral blood mononuclear cells (PBMC) from healthy adult donors. Non-stimulated or stimulated PBMC … …OnLine Journal of Biological Sciences, Vol. 18, Issue 1 · 7 Jan 2018 · 6,849 accessesView PDFCite
Research ArticleOpen accessIn the abstractLIGHTWEIGHT VIGILANT PROCEDURE TO IMPLEMENT SECURITY MEASURES IN HIGHLY ROVING MILITARY OPERATIONSJ. Udhayan, Rajesh BabuThe performance of Mobile Ad hoc Network (MANET) becomes questionable in highly roving and mission critical application like military operation. Security measures like encryption, authentication, digital signature has been proposed for MANET. However all those mechanisms need some kind of static infrastructure and it is extremely difficult to implement such an infrastructure throughout the military mission. Therefore in this work, … …Journal of Computer Science, Vol. 9, Issue 10 · 18 Sep 2013 · 6,648 accessesView PDFCite
Research ArticleOpen accessIn the abstractAdaptogenic Potentials of Cyphostemma glaucophilla Aqueous Leaf ExtractOjogbane Eleojo, Nwodo Okwesili Fred Chiletugo, Omale JamesCytophostemma glaucophilla aqueous extract is used in Kogi and Kwara States of Nigeria to treat Kwashiorkor and to boost immunity. As part of the effort to evaluate its effect on stress, it was screened for adaptogenic potentials. This investigation was conducted using albino rats to determine the ability of this plant to increase non specific resistance against physical, biological and … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 3 · 4 Sep 2013 · 7,124 accessesView PDFCite
Research ArticleOpen accessIn the abstractPossible Mechanism of Plumbago zeylanica in Prevention of Hepatic Dammage in Wistar RatRohit Goyal, Pyare Lal SharmaPlumbago zeylanica root has been used traditionally to treat various body ailments including liver diseases. The present study was designed to investigate the hepatoprotective effects of standardized methanolic extract of Plumbago zeylanica root on paracetamol, CCl4 and alcohol induced hepatic injuries in rats and its possible mechanism(s) of hepatoprotection. Administration of hepatotoxicants like paracetamol (3 g kg-1, p.o.) or CCl4 … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 3 · 20 Nov 2012 · 7,641 accessesView PDFCite
Research ArticleOpen accessIn the abstractLemon Pepper Fruit Extract (Zanthoxylum acanthopodium DC.) Suppresses the Expression of Inflammatory Mediators in Lipopolysaccharide-Induced Macrophages In VitroYanti, Theodorus Eko Pramudito, Nerissa Nuriasari, Katarina JulianaProblem statement: Lemon pepper fruits (Zanthoxylum acanthopodium DC.; Rutaceae) have been used as a traditional source against stomach ache by Batak people in North Sumatera province, Indonesia. However, its scientific evidence for treatment of inflammatory disorders particularly gastritis has not been reported. Approach: Here, we investigated the inhibitory effects of Lemon Pepper Fruit Extract (LPFE) against inflammatory biomarkers by conducting … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 4 · 14 Feb 2012 · 9,587 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Negative Environmental Changes on the Sea and its Impact on the Aspects of Economic, Social and Health of the Fishermen Living in the East Coast Zone of Peninsular MalaysiaBahaman Abu Samah, Hayrol Azril Mohamed Shaffril, Jeffrey Lawrence D’Silva, Jegak UliProblem statement: The sea has never been the same as before. Due to the environment and human factors, lot of negative environmental changes can be detected at the sea. Apparently, one of the main dependents of the sea which is the fishermen has the potential to be affected with such changes. Approach: This study would like to discover whether these … …American Journal of Environmental Sciences, Vol. 7, Issue 6 · 11 Jan 2012 · 7,292 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnticonvulsant Effect of Pitavastatin in Mice Induced by PentylenetetrazoleKhayatnouri MirhadiProblem statement: The 3-Hydroxy-3-Methylglutaryl-CoA (HMG-CoA) reductase inhibitors (statins) have been unequivocally shown to reduce cardiovascular morbidity and mortality by their lipid-lowering actions. It has been suggested that statins appear to have therapeutic benefits in diseases that are unrelated to elevated serum cholesterol levels. The aim of this study was to evaluation the effect of intraperitoneally injection of different doses of … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 4 · 11 Jan 2012 · 7,511 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Intraperitoneally Injection of Different Doses of Lovastatin on Pain and Inflammatory Response Induced by Formalin in MiceKhayatnouri MirhadiProblem statement: The 3-Hydroxy-3-Methyl Glutaryl-CoA (HMG-CoA) reductase inhibitors (statins) have been unequivocally shown to reduce cardiovascular morbidity and mortality. Their lipid-lowering actions are by reversible and competitive inhibition of the enzyme HMG-CoA reductase, a precursor of cholesterol. It has been suggested that statins appear to have therapeutic benefits in diseases that are unrelated to elevated serum cholesterol levels, such as … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 4 · 11 Jan 2012 · 7,685 accessesView PDFCite