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420 results for “Administration”
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Research ArticleOpen accessIn the abstractKidney Function Indices in Mice after Long Intake of Agaricus brasiliensis Mycelia (=Agaricus blazei, Agaricus subrufescens) Produced by Solid State CultivationDalla Santa Herta Stutz, Rubel Rosália, Vitola Francisco Menino Destéfanis et al.Problem statement: Agaricus brasiliensis (=Agaricus blazei, Agaricus subrufescens) or Sun mushroom has widespread use for potential health benefits such anti-tumor and immunomodulatory effects. Studies detected that others edible mushrooms affected renal metabolism and despite the widespread use of A. brasiliensis there are no studies that address biological effects on the renal function indices after their oral administration. Therefore, this study … …OnLine Journal of Biological Sciences, Vol. 9, Issue 1 · 31 Mar 2009 · 8,149 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effects of Recombinant Human Erythropoietin and Tamoxifen on Growth and Angiogenesis of Mammary Tumor in Sprague-Dawley RatA. K. Sairah, A. Rasedee, O. Sheikh et al.Problem statement: Erythropoietin receptor (EPOR) has been detected in breast cancer cells and speculated to be involved in cancer growth, viability and angiogenesis. This has risen suspicious that EPO administration may enhance the severity of cancer. Approach: This study was undertaken to determine the effects of rHuEPO, Tamoxifen and their combination on the growth and angiogenesis of mammary tumor. Female … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 1 · 31 Mar 2009 · 7,804 accessesView PDFCite
Research ArticleOpen accessIn the abstractPersonal Characteristics Affecting Agricultural Extension Workers' Job Satisfaction LevelAli Asadi, Fereshteh Fadakar, Zahra Khoshnodifar et al.Problem Statement: One of the closely associated concepts with performance of an organization is job satisfaction. The purpose of this study was to investigate the relationship between personal characteristics and job satisfaction. Approach: A survey of 52 extension workers was conducted in Fars Province, southern Iran. To collect data, a questionnaire including Bray field and Rothe Job Satisfaction Index was … …Journal of Social Sciences, Vol. 4, Issue 4 · 31 Dec 2008 · 8,240 accessesView PDFCite
Research ArticleOpen accessIn the abstractConstructing a Grid Simulation for E-Governance Applications Using GridSimMrs. P. Sumathi, M. PunithavalliThis study provides a design framework for the adoption of grid computing for e-governance applications. Problem statement: E-Governance is the application of information and communication technology to achieve efficiency, effectiveness, transparency and accountability in Government to Government (G2G), Government to Employee (G2E), Government to Citizen (G2C) and Government to Business (G2B). It enables citizens to make best use of automated … …Journal of Computer Science, Vol. 4, Issue 8 · 31 Aug 2008 · 6,766 accessesView PDFCite
Research ArticleOpen accessIn the abstractDeterministic Parallel Sorting Algorithm for 2-D Mesh of Connected ComputersHamed Al Rjoub, Arwa Zabian, Ahmad OdatSorting is one of the most important operations in database systems and its efficiency can influences drastically the overall system performance. To accelerate the performance of database systems, parallelism is applied to the execution of the data administration operations. We propose a new deterministic Parallel Sorting Algorithm (DPSA) that improves the performance of Quick sort in sorting an array of … …Journal of Computer Science, Vol. 4, Issue 6 · 30 Jun 2008 · 6,824 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Novel Rodent Model of Autism: Intraventricular Infusions of Propionic Acid Increase Locomotor Activity and Induce Neuroinflammation and Oxidative Stress in Discrete Regions of Adult Rat BrainDerrick F. MacFabe, Karina Rodríguez-Capote, Jennifer E. Hoffman et al.Innate neuroinflammatory changes, increased oxidative stress and disorders of glutathione metabolism may be involved in the pathophysiology of autism spectrum disorders (ASD). Propionic acid (PPA) is a dietary and gut bacterial short chain fatty acid which can produce brain and behavioral changes reminiscent of ASD following intraventricular infusion in rats. Adult Long-Evans rats were given intraventricular infusions of either PPA … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 12,613 accessesView PDFCite
Research ArticleOpen accessIn the abstractHormetic and Non-Hormetic Dose-Response Functions in Stress Effects on Memory and Synaptic Plasticity: Issues and MechanismsPhillip R. Zoladz, David M. DiamondOver a century of behavioral research has shown that stress can exert both positive and negative effects on memory. We have explored the idea that the complex effects of stress on learning and memory can be characterized by hormetic- and non-hormetic dose-response functions, in which stress may either stimulate or impair brain memory mechanisms, depending, in part, on the timing … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 8,184 accessesView PDFCite
Research ArticleOpen accessIn the abstractSesame Oil As A Protective Agent Against Doxorubicin Induced Cardio Toxicity In RatKaneez F. Shad, Suhail Al-Salam, Alaaeldin A. HamzaThe therapeutic value of doxorubicin (DXO) as anticancer antibiotic is limited by its cardiotoxicity. This study aimed to investigate the protective effect of sesame oil against DXO-induced cardiotoxicity and oxidative stress. The administration of DXO (20 mg/kg) to Wister male rats, increased serum aspartate aminotransferase and creatine kinase activities (as cardiotoxicity indices) as well as cardiac malondialdehyde and protein carbonyl … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 4 · 31 Dec 2007 · 7,670 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunodeficient Parameters in the HIV-1 Transgenic Rat ModelSulie L. Chang, Frank Ocasio, Jose A. BeltranRecently an HIV-1 transgenic (HIV-1Tg) rat model was created that carries a gag-pol-deleted HIV-1 genome under the control of the HIV-1 viral promoter. However, other viral proteins are expressed in most organs and tissues, and are found in the circulating blood. Since HIV-1 targets the immune system in humans, we examined two immunological parameters, leukocyte-endothelial adhesion (LEA) and inflammatory cytokine … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 7,834 accessesView PDFCite
Research ArticleOpen accessIn the abstractTacrolimus Dosing Challenges in an African American ChildTeresa V. Lewis, Tracy M. Hagemann, Martin A. TurmanIt has been suggested that African Americans have decreased effectiveness with immunosuppressive drugs. Data regarding the pharmacokinetics of tacrolimus in African Americans are limited. We present the case of an African American child in whom management of nephrotic syndrome caused by focal segmental glomerulosclerosis has been challenging due to unpredictable patient specific pharmacokinetic disposition of tacrolimus. Racial differences have been … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 3 · 30 Sep 2007 · 6,708 accessesView PDFCite