Literature ReviewOpen accessIn the abstractThe Effects of Glucocorticoids on Trabecular Meshwork and its Role in GlaucomaAlina GenisPrimary Open-Angle Glaucoma (POAG), an optic neuropathy that is a leading cause of irreversible blindness, has been studied extensively in hopes of better understanding its underlying mechanism. Glucocorticoids (GC) are commonly used to treat inflammatory ocular conditions but are also known to increase the risk of glaucoma by raising Intraocular Pressure (IOP) in susceptible individuals, leading to steroid-induced glaucoma. Based … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 4 · 14 Oct 2015 · 8,219 accessesView PDFCite
Research ArticleOpen accessIn the abstractBispectral Analysis of Scalp Electroencephalograms: Quadratic Phasecoupling Phenomenon in Detecting Brain TumorV. Salai Selvam, S. ShenbagadeviSince the power spectral analysis of a non-Gaussian process generated by a nonlinear mechanism e.g., EEG, does not provide much information on the underlying nonlinear dynamics due to the lack of phase information, the higher-order statistics such as the bispectra are used to better understand the underlying nonlinear dynamics e.g., the quadratic phase coupling phenomena. The quadratic phase couplings have … …American Journal of Applied Sciences, Vol. 10, Issue 3 · 27 Mar 2013 · 6,537 accessesView PDFCite
Research ArticleOpen accessIn the abstractMulberry Fruits Extract Mitigate Vascular DementiaPratchaya Kaewkaen, Jintanaporn Wattanathorn, Terdthai Thong-Un et al.To date, Vascular Dementia (VaD) is the second most commonly found dementia following Alzheimer�s disease. Though VaD is still increasing its importance, the therapeutic efficacy is still not in satisfaction level. Therefore, the searching for an acceptable cheap and safe neuroprotective agent is in a great demand. Based on the neuroprotective and cognitive enhancing effects in alcohol neurotoxicity of mulberry … …American Journal of Applied Sciences, Vol. 9, Issue 11 · 1 Sep 2012 · 6,967 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Mulberry Fruit Powder in Animal Model of StrokePratchaya Kaewkaen, Terdthai Tong-Un, Jintanaporn Wattanathorn et al.Stroke is the leading cause of death and the important cause of disability worldwide. Presently, the effectiveness of therapeutic strategy is still very limited. Based on the role neuroprotective effect of substance possessing antioxidant effect previously reported, we hypothesized mulberry fruit a substance possessing anti-oxidant activity, might be able to protect against cognitive impairment induced by stroke or cerebral ischemia. … …American Journal of Agricultural and Biological Sciences, Vol. 7, Issue 3 · 15 Aug 2012 · 9,039 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Stringent Authorization using Principles and Policy for Grid ComputingA. R. Jayasudha, T. PurusothamanProblem statement: The current information security mechanisms are insufficient to address authorization issues. The access control models today are mostly static and they are not wellsuited for the service-oriented environments where information access is dynamic in nature. Traditional authorization security techniques do not directly address these concerns as they primarily use access control lists for authorization, where the user whose … …Journal of Computer Science, Vol. 7, Issue 8 · 8 Aug 2011 · 6,634 accessesView PDFCite
Research ArticleOpen accessIn the abstractRole of Evaporation in Degrading the "Oil Lakes"Al Rashed Ahamad, Colin BarkerProblem statement: Oil Spills are degraded by aerobic bacteria, water washing, evaporation and oxidation. In the absence of water the first two of these processes cannot operate. This is the situation in the low rainfall environment of the Kuwaiti desert where oil lakes still persist 20 years after the initial spills. The oils contain longer chain n-alkanes but have lost … …American Journal of Environmental Sciences, Vol. 7, Issue 3 · 11 Jul 2011 · 6,747 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvidence of Oxidative Stress in Autism Derived from Animal ModelsXue Ming, Michelle A. Cheh, Carrie L. Yochum et al.Autism is a pervasive neurodevelopmental disorder that leads to deficits in social interaction, communication and restricted, repetitive motor movements. Autism is a highly heritable disorder, however, there is mounting evidence to suggest that toxicant-induced oxidative stress may play a role. The focus of this article will be to review our animal model of autism and discuss our evidence that oxidative … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 7,115 accessesView PDFCite
Research ArticleOpen accessIn the abstractOn the Hormetic Behaviour of Drugs Binding to Different Redox States of Amine Oxidase EnzymesDeepak Narang, G. Reid McDonald, David J. Smith et al.Classical monoamine oxidases and copper-containing semicarbazide-sensitive amine oxidases are drug targets for a variety of established and novel pharmaceuticals used to treat conditions such as depression, Parkinsonism and inflammatory disorders. Development of enzyme inhibitors, both historically and currently, assumes an underlying adherence of these enzymes to Michaelis-Menten kinetic principles. In this mini-review, we discuss historical data from several laboratories and … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 6,928 accessesView PDFCite
Research ArticleOpen accessIn the abstractElucidating the Mechanism(s) of Hormesis at the Cellular Level: The Universal Cell ResponsePaul S. AgutterMany environmental stressors elicit biphasic effects from single cells. Such cellular hormesis may be interpreted in terms of (a) the superimposition of simple biochemical processes or (b) the non-specific behaviour of the cell. The latter approach is emphasized in this article and identified with the universal cell response (UCR); however, the importance of identifying molecular-level concomitants of the UCR is … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 13,112 accessesView PDFCite