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62 articles for “therapeutic agent”
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EditorialOpen accessIn the abstractCommentary-How do we Improve Training for Receptor Research?Marilee Ann BenoreThis issue of the American Journal of Biochemistry and Biotechnology features articles about receptor-ligand interactions that are critical to the wellbeing of all living organisms. The importance of the field of receptor research is supported by the large number of articles published in journals, the numerous specialty journals, the international conferences and the percentage of legal drugs on the market … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 4 · 8 Dec 2015 · 8,058 accessesView PDFCite
Research ArticleOpen accessIn the abstractATRA AS A POTENTIAL ANTIMETASTATIC AGENT IN COLORECTAL ADENOCARCINOMARobert Edwards, Kambiz Afrasiabi, Kehui WangThe family of Retinoic acid compounds have long been the subject of intense study and interest as chemo prophylactic agents. This dates back to their therapeutic effect in leukoplakia Where ATRA was shown to lead to the reversal of premalignant lesions and Subsequent reports on their use in metastatic colorectal adenocarcinoma and a vast array of other malignant disorders as … …OnLine Journal of Biological Sciences, Vol. 14, Issue 2 · 26 Mar 2014 · 7,348 accessesView PDFCite
Research ArticleOpen accessIn the abstractCHRONIC NEONATAL DIAZOXIDE THERAPY IS NOT ASSOCIATED WITH ADVERSE EFFECTSMichele M. Cox, Christopher C. Wendler, Ildiko Erdelyi et al.Diazoxide is an ATP-sensitive potassium channel (KATP) agonist that has been shown to neuroprotective effects. These observations raise the possibility that diazoxide may have potential as a therapeutic agent for other applications. This study investigated (1) the long term effects of chronic neonatal administration of diazoxide and (2) the role of KATP on murin behavior and neurohistology. C57B/6J pups were … …OnLine Journal of Biological Sciences, Vol. 14, Issue 1 · 27 Jan 2014 · 7,452 accessesView PDFCite
Research ArticleOpen accessIn the abstractComparative Study of In Vitro Antibacterial Activity of Miswak Extracts and Different ToothpastesSarmad Ghazi MohammedThis study determines the antimicrobial efficacy of miswak (aqueous and alcoholic) extracts comparing with five different toothpastes, which are available in Iraqi market, against different kinds of bacteria. The antibacterial efficacy of aqueous and alcoholic extracts of Salvadora persica and different kinds of toothpastes was studied against different cariogenic and pathogenic bacteria including Streptococcus mutans, Lactobacillus acidophilus, Escherichia coli, Staphylococcus … …American Journal of Agricultural and Biological Sciences, Vol. 8, Issue 1 · 19 Mar 2013 · 8,896 accessesView PDFCite
Research ArticleOpen accessIn the abstractMoringa Oleifera Leaves Extract Attenuates Male Sexual DysfunctionWipawee Thukhammee, Supaporn Muchimapura, Sitthichai Iamsa-ard et al.Problem statement: At present, the novel agent that is effective, cheap and easy to approach for treating male sexual dysfunction is required due to the current poor therapeutic efficacy. Though Moringa oleifera is reputed for aphrodisiac activity in traditional folklore, no scientific evidence is available. Therefore, we aimed to determine the effect of M.oleifera leaves extract on male sexual behaviors … …Neuroscience International, Vol. 3, Issue 1 · 1 Sep 2012 · 32,907 accessesView PDFCite
Research ArticleOpen accessIn the abstractNeuroprotective Effect against Cerebral Ischemia of Passiflora foetidaJintanaporn Wattanathorn, Natcha Sattroopinat, Terdthai Tong-Un et al.Problem statement: Although cerebral ischemia induced by stroke has been regarded as the important problem worldwide, the therapeutic efficacy is still inadequate. Since the free radicals are implicated in the pathophysiology of cerebral ischemia, the prophylactic protection against stroke with neuroprotective agent possessing antioxidant effect has gained much attention. Therefore, this study was designed to determine whether the alcoholic extract … …American Journal of Applied Sciences, Vol. 9, Issue 4 · 16 Feb 2012 · 8,245 accessesView PDFCite
Research ArticleOpen accessIn the abstractInteraction of Aqueous Extract of Trigonella Foenum-Graecum Seeds with Glibenclamide in Streptozotocin Induced Diabetic RatsV. K. Lal, P. P. Gupta, P. Tripathi, A. PandeyProblem statement: Interaction between herbs and drugs may increase or decrease the pharmacological or toxicological effects of either component. Herb traditionally used to decrease glucose concentrations in diabetes could theoretically precipitate hypoglycaemia if taken in combination with conventional drugs. Approach: The present study was undertaken to determine the interaction of Glibenclamide, a Sulphonylurea with Trigonella foenum-graecum seed extract, an herbal … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 4 · 31 Dec 2011 · 8,017 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Intramammary Injection of Nigella Sativa on Somatic Cell Count and Staphylococcus Aureus Count in Holstein Cows with S. aureus Subclinical MastitisHamideh Ghodrati Azadi, Nima Farzaneh, Zahra Baghestani et al.Problem statement: The seeds of Nigella sativa Linn. (Ranunculaceae) known as black seed or black cumin, are used in herbal medicine all over the world for the treatment and prevention of a number of diseases and conditions that include asthma, diarrhea and dyslipidaemia. Approach: In this study the effect of intramammary injection of Nigella Sativa Extract (NSE) in paraffin on … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 1 · 26 Apr 2011 · 8,300 accessesView PDFCite
Research ArticleOpen accessIn the abstractPreliminary Study on Immunomodulatory Effect of Sarang-Semut Tubers Myrmecodia tuberosa and Myrmecodia pendensTriana Hertiani, Ediati Sasmito, Sumardi, Maria UlfahProblem Statement: Sarang-Semut tubers, Myrmecodia tuberosa and M. pendens (Rubiaceae) are both medicinal plants originating from Papua which have broad range of therapeutic values including those to improve vitality. Nevertheless, no scientific proof is available so far on their immunomodulatory effect. The purpose of this study was to reveal the potency of Sarang-Semut tubers as immunomodulatory agent by evaluating their … …OnLine Journal of Biological Sciences, Vol. 10, Issue 3 · 30 Sep 2010 · 13,403 accessesView PDFCite
Research ArticleOpen accessIn the abstractPhysiological Study on the Effect of Acalypha wilkesiana Leaves Extract on Streptozotocin-Induced Experimental Diabetes in Male MiceAtef M. Al-AttarProblem statement: Diabetes mellitus is a chronic disease that causes serious health complications and it is now one of the most common non-communicable diseases globally. It is the fourth or fifth leading cause of death in most high-income countries and there is substantial evidence that it is epidemic in many economically developing and newly industrialized nations. Recently, there has been … …Current Research in Medicine, Vol. 1, Issue 1 · 30 Jun 2010 · 74,650 accessesView PDFCite