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Research ArticleOpen accessIn the abstractClinical and Reproductive Pathological Changes Associated with Brucella melitensis and its Lipopolysaccharides in Female Mice Via Oral InoculationFaez Firdaus Jesse Abdullah, Lawan Adamu, Nur Hazirah et al.Brucella melitensis (B. melitensis) are Gram-negative, aerobic, facultative intracellular bacteria that cause brucellosis that usually leads to abortion in sheep and goats. Three groups of equal number of 24 healthy female mice were used as animal models. They were orally inoculated with 0.4 mL of phosphate Buffered Saline (PBS-Control group), 0.4 mL of 109 cfu of B. melitensis and 0.4 … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 3 · 30 Aug 2013 · 8,572 accessesView PDFCite
Research ArticleOpen accessIn the abstractInfluence of a Low-Level Semiconductor Gallium Arsenate Laser in Experimental Envenomation Induced by Bothrops atrox Snake VenomElziliam Aranha De Sousa, José Adolfo Homobono Machado Bittencourt, Nayana Keyla Seabra De Oliveira et al.Bothrops atrox is responsible for the majority of snakebite accidents in Brazilian Amazon and its venom can cause prominent local tissue damage. Experimental groups consisted of five male mice, each administered either B. atrox Venom (VB), B. atrox Venom + Antivenom (VAV), B. atrox Venom + Laser (VL), B. atrox Venom + Antivenom + Laser (VAVL), or Sterile Saline Solution … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 4 · 29 Dec 2012 · 7,500 accessesView PDFCite
Research ArticleOpen accessIn the abstractPossible Mechanism of Plumbago zeylanica in Prevention of Hepatic Dammage in Wistar RatRohit Goyal, Pyare Lal SharmaPlumbago zeylanica root has been used traditionally to treat various body ailments including liver diseases. The present study was designed to investigate the hepatoprotective effects of standardized methanolic extract of Plumbago zeylanica root on paracetamol, CCl4 and alcohol induced hepatic injuries in rats and its possible mechanism(s) of hepatoprotection. Administration of hepatotoxicants like paracetamol (3 g kg-1, p.o.) or CCl4 … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 3 · 20 Nov 2012 · 7,638 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Role of Inflammation in Development and Therapy of Malignant MesotheliomaArti Shukla, Jill MillerMalignant Mesothelioma (MM) is an asbestos related malignancy with a poor prognosis and limited therapeutic approaches. The pathogenesis of MM has been linked to asbestos induced inflammation. Asbestos exposure results in reactive oxygen species generation, infiltration of inflammatory cells and prolonged release of multiple cytokines, oxidants and growth factors. The role of inflammation in MM has led to the evaluation … …Current Research in Medicine, Vol. 3, Issue 2 · 30 Aug 2012 · 7,437 accessesView PDFCite
Research ArticleOpen accessIn the abstractHepatic and Renal Histological Alterations Induced by Topical Hydroquinone AdministrationBashir M. Jarrar, Maher M. Alenezi, Abdullah Al-Hiri, Yazun JarrarProblem statement: Although the regulatory agencies of the United States and Europe banned hydroquinone in cosmetics skin lightening but it is still used in most of Middle East countries, including Saudi Arabia. Few studies were carried out on the histological alterations of hydroquinone on kidney and liver. Approach: The present study was carried out to investigate the histological alterations in … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 1 · 7 Apr 2012 · 9,653 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Storing Temperature on Hepatotoxicity and Nephrotoxicity of Ifosfamide in Female RatFalah Mohammed AzizProblem statement: Ifosfamide (IFO) is a cytotoxic alkylating drug used for the treatment of a variety of cancers, although it has been found to induce certain hematological, hepatotoxic and nephrotoxic side effects. This drug is widely used in developing country, especially Iraq, but without caring too much to the storing temperature due to low drug maintaining facilities. The present work … …OnLine Journal of Biological Sciences, Vol. 12, Issue 1 · 19 Mar 2012 · 7,883 accessesView PDFCite
Research ArticleOpen accessIn the abstractDetermining Potential Sites for Runoff Water Harvesting using Remote Sensing and Geographic Information Systems-Based Modeling in SinaiHossam H. Elewa, Atef A. Qaddah, Ayman A. El-FeelProblem statement: Sinai is increasingly suffering from an overwhelming water crisis. Runoff Water Harvesting (RWH) could be a solution for this problem. The determined promising drainage basins for RWH could be used by the decision makers to propose appropriate controlling systems to overcome the problem of water scarcity and for implementing runoff farming and rain-fed agriculture. Approach: Remote sensing, geographic … …American Journal of Environmental Sciences, Vol. 8, Issue 1 · 15 Feb 2012 · 8,483 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effect of Citrullus colocynthis Pulp Extract on the Liver of Diabetic Rats a Light and Scanning Electron Microscopic StudyMohammad Khalil, Gamal Mohamed, Mohammad Dallak et al.Problem statement: The goal of the current investigation was to clarify the effects of Citrullus colocynthis pulp extract on the structure of the liver of diabetic rats at both light and scanning electron microscopic levels. Approach: Forty-eight adult male albino rats were equally allocated into four groups: Group1: control, Group 2: Citrullus colocynthis-treated, Group 3: diabetic rats and Group4: diabetic … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 3 · 30 Sep 2010 · 9,478 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Novel Odor Key Technique for Security Applications Using Electronic Nose SystemMahmoud Z. IskandaraniProblem statement: A novel approach to security applications that makes use of odors as password generators is developed and tested. The developed system detects and converts odor signals that are randomly selected to binary signals and then intelligently compares them with previously stored values. Approach: The interface device in question then either opens its interface if comparison is successful or … …American Journal of Applied Sciences, Vol. 7, Issue 8 · 31 Aug 2010 · 7,186 accessesView PDFCite
Research ArticleOpen accessIn the abstractSoil-moisture Retention Characteristics of Earth Materials in the Weathering Profile over a Porphyritic Biotite GraniteJohn Kuna RajProblem statement: Three broad morphological zones and several sub-zones were differentiated within the weathering profile based on variations in earth materials and the degree of preservation of original bedrock minerals, textures and structures. Approach: The topmost Zone I (Grade 6) is some 12 m thick and comprises completely weathered bedrock materials (mainly a stiff, clayey sand) with indistinct relict bedrock … …Current Research in Geoscience, Vol. 1, Issue 1 · 30 Jun 2010 · 9,466 accessesView PDFCite