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75 articles for “hypothesized”
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Research ArticleOpen accessIn the abstractEffects of Unilateral Cervical Vagotomy on Murine Dendritic CellsDaniel Sanzio Gimenes da Cruz, Ana Paula Nascimento de Lima, Patrícia Benites Gonçalves da Silva et al.The cholinergic anti-inflammatory pathway has been demonstrated to be an important mechanism that modulates several inflammatory diseases. This modulation occurs upon activation of the vagus nerve, which modulates splenic macrophages and lymphocytes through the predominant neurotransmitter, Acetylcholine (ACh). We hypothesized that this modulation could also take place in dendritic cells, as these cells represent a link between the innate and … …American Journal of Immunology, Vol. 11, Issue 2 · 12 Jul 2015 · 6,948 accessesView PDFCite
Research ArticleOpen accessIn the abstractDocking and Molecular Dynamics Simulations in Potential Drugs Discovery: An Application to Influenza Virus M2 ProteinMarine E. Bozdaganyan, Philipp S. Orekhov, Nicola L. Bragazzi et al.Molecular docking is a common method for searching new potential drugs. Improvement of the results of docking can be achieved by different ways-one of them is molecular dynamics simulations of protein-ligand complexes. As a model for our research we chose M2 membrane protein from influenza virus. M2 protein is a high selective tetrameric pH-gated proton channel. It was previously shown … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 3 · 11 Nov 2014 · 8,669 accessesView PDFCite
Research ArticleOpen accessIn the abstractDUAL ROLES OF CANCER CELL-EXPRESSED IMMUNOGLOBULINS IN CANCER IMMUNOLOGYGregory Lee, Cheng-Yuan Huang, Suefay Liu et al.While the expression of immunoglobulins and T cell receptors on cancer cells has been well-established for decades, the potential roles and mechanisms of action of these cancerous antigen receptors have not been fully elucidated. A monoclonal antibody designated as RP215, which reacts specifically with the carbohydrate-associated epitope located on the heavy chain region of cancerous immunoglobulins and T cell receptors, … …American Journal of Immunology, Vol. 10, Issue 3 · 2 Oct 2014 · 7,870 accessesView PDFCite
Research ArticleOpen accessIn the abstractTHE PREVALENCE OF DEPRESSION AND ITS RISK FACTORS AMONG MALAY ELDERLY IN RESIDENTIAL CARER. Normala, C. Azlini, M. J. Nurul, Z. M. LukmanThe motivation for the study is to improve the quality of life for elderly in residential care particularly the mental health aspect. Hence, the aim of this study is to examine the prevalence of depression and to identify risk factors related to depression among Malay elderly in residential care. Changes in social structure and economic status have shifted the direction … …American Journal of Applied Sciences, Vol. 11, Issue 9 · 3 Jul 2014 · 7,127 accessesView PDFCite
Research ArticleOpen accessIn the abstractROLE OF SALINITY IN PRECIPITATION AND WELL WATER DEPTH RELATIONSHIPManoj K. JhaExcessive groundwater pumping can decrease the amount of fresh water flowing towards the coastal discharge areas, allowing salt water to be drawn into the fresh water zones of coastal aquifers. This process gets complicated with the frequent change behavior of groundwater levels in observation wells. The fluctuation happens due to various reasons but can be directly correlated with the precipitation … …American Journal of Engineering and Applied Sciences, Vol. 7, Issue 1 · 27 Mar 2014 · 7,952 accessesView PDFCite
Research ArticleOpen accessIn the abstractMISCONSTRUING AGENCY: ISSUES RELATED TO FREE WILL AND DETERMINISMShirley Matile OgletreeAgency (related to intentionality and the importance of choices) and free will (&#34could have done otherwise&#34) have been confounded in previous psychological research, with assessments and manipulations of free will often including items related to agency. Therefore, correlates previously associated with free will may, to some extent, be based on agentic assumptions. In this study 152 college students from a … …Journal of Social Sciences, Vol. 10, Issue 1 · 15 Feb 2014 · 7,547 accessesView PDFCite
Research ArticleOpen accessIn the abstractRnai Induced Wing Modification in Leon Mutant Drosophila: A Developmental AnalysisSandeep Satapathy, Cheng Ting ChienThe precision of growth of an animal is meticulously regulated by extrinsic and intrinsic factors, with focus on maintenance of organismal homeostasis. The clue to change in physiology or metabolism of an organism, at times can be derived from the changes in phenotypes. In the Drosophila melanogaster model system, GAL 4-overexpressed RNAi driver males (Mini-White Marker), targeted against specific genes, … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 4 · 20 Dec 2013 · 6,717 accessesView PDFCite
Research ArticleOpen accessIn the abstractATTACHMENT STYLE AS A PREDICTOR OF RISKY SEXUAL BEHAVIOR IN ADOLESCENTSAmber Paulk, Ryan ZayacThe aim of the current study was to examine attachment style as a predictor of risky sexual behavior in a younger, more vulnerable sample than previously investigated in the literature: High school aged adolescents. The hypothesized associations among the variables were partially supported. Contrary to our predictions, there was no significant association between avoidance and risky sexual behavior. However, higher … …Journal of Social Sciences, Vol. 9, Issue 2 · 20 Aug 2013 · 8,184 accessesView PDFCite
Research ArticleOpen accessIn the abstractManipulation of Photosynthesis in Grape (Vitis vinifera) CV. ‘Flame’ by the Application of Two Sucrose AnalogsM. E. Tiznado-Hernandez, J. A. Orozco-Avitia, A. J. Ojeda-Contreras, A. A. Gardea-BejarThe translocation of photosynthates from the leaves is important for the accumulation of sugars in grape berries. Two sucrose analogs were applied at post-veraison to determine their effects on leaf photosynthesis. It is hypothesized that the signal of sugar accumulation in leaves will bring a reduction in photosynthesis and an increase in the photosynthate translocation rate to the berries. The … …American Journal of Agricultural and Biological Sciences, Vol. 8, Issue 1 · 9 Feb 2013 · 7,927 accessesView PDFCite
Research ArticleOpen accessIn the abstractMathematical Model Predicting the Critical Heat Flux of Nuclear ReactorsChien-Hsiung Lee, Lih-Wu Hourng, Kuo-Wei LinBoiling heat transfer system keeps a nuclear power plant safe without getting over-heated. Crisis will occur if the dissipated heat flux exceeds the critical heat flux value. This study assumes the flow boiling system at high heat flux is characterized by the existence of a very thin liquid layer, known as the &#34sublayer&#34, which is trapped between the heated surface … …Journal of Computer Science, Vol. 8, Issue 12 · 12 Dec 2012 · 7,695 accessesView PDFCite