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36 articles for “hydrophobic”
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Research ArticleOpen accessIn the abstractIntrinsically Unstructured Proteins: Potential Targets for Drug DiscoveryPathan Salma, Chintan Chhatbar, Sriram SeshadriProblem statement: The function of a protein is dependent on its three-dimensional structure. However, numerous proteins lacking intrinsic globular 3D structure under physiological conditions had been recognized. These proteins are frequently involved in some of the most critical cellular control mechanisms and it appears that their rapid turnover, aided by their unstructured nature in the unbound state, provides a level … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 7,578 accessesView PDFCite
Research ArticleOpen accessIn the abstractPrediction of a Putative Functional Region in the Human Bax Protein by Computational AnalysisMaría Sánchez-Aguilar, Laurence A. Marchat, Absalom ZamoranoStructural domains are relevant elements for interactions between Bcl-2 family members to regulate apoptosis and cell survival. Although BH1-BH4 domains can be identified by their sequence and selective occurrence in Bcl-2-family members, structural regions have not been entirely determined yet. The functional residues of Bax, the most representative pro-apoptotic protein of the human Bcl-2 family, remain almost unknown. Here, we … …American Journal of Infectious Diseases, Vol. 3, Issue 2 · 30 Jun 2007 · 7,230 accessesView PDFCite
Research ArticleOpen accessIn the abstractBinding of the scutellarin to albumin using tryptophan fluorescence quenching, CD and FT-IR spectraJianniao Tian, Jiaqin Liu, Zhide Hu, Xingguo ChenThe binding of scutellarin with bovine serum albumin (BSA) was investigated at three temperatures, 296k, 310K, and 318K, by the fluorescence, circular dichroism (CD) and fourier transform infrared spectroscopy (FT-IR) at pH 7.40. The binding parameters were determined by Stern-Volmer equation. The thermodynamic parameters were calculated according to the dependence of enthalpy change on the temperature as follows:ΔH0 and ΔS0 … …American Journal of Immunology, Vol. 1, Issue 1 · 31 Mar 2005 · 13,643 accessesView PDFCite
Research ArticleOpen accessIn the abstractModel Classification for Predicting the Post-Translational Modification (PTM) Glycosylation in Sequence O Using an Extreme Gradient Boosting AlgorithmDamayanti, Sutyarso et al.Post Translational Modification (PTM) is an important mechanism involved in regulating protein function. Post-translational modification refers to the addition of covalent and enzymatic modifications of proteins in protein biosynthesis, which has an important role in modifying protein function and regulating gene expression. One of the post-translational modifications is glycosylation. Glycosylation is the addition of a sugar group to a protein … …Journal of Computer Science, Vol. 20, Issue 7 · 29 Apr 2024 · 5,554 accessesView PDFCite
Research ArticleOpen accessIn the abstractPreparation of Antimicrobial Collagen Casings with High Mechanical PropertiesZhike Xie, Shuyan Yu, Ming He et al.Tea Polyphenols (TP) has received much attention for their excellent antioxidant and antibacterial activities. Some additives (such as sodium alginate and sodium pyrophosphate) have good hydrophobicity which have influence on the mechanical properties of food. The effect of TP on the antibacterial activity of collagen casing was investigated, the effect of addition of TP, sodium pyrophosphate and sodium alginate on … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 3 · 2 Sep 2020 · 6,627 accessesView PDFCite
Research ArticleOpen accessIn the abstractHuman Insulin Modulation of Escherichia coli Adherence and ChemotaxisKarolina Klosowska, Balbina J. PlotkinEscherichia coli exhibited increased hydrophobicity and mannose-resistant epithelial cell adherence after growth in the presence of human insulin (2 μU mL-1 or 200 μUmL-1 insulin, respectively) with glucose (100 mg dL-1). Capsule production and hemagglutination were unaffected by insulin and glucose. Chemotactic attraction to glucose as compared to insulin or glucose alone was enhanced by the presence of insulin. Insulin … …American Journal of Infectious Diseases, Vol. 2, Issue 4 · 31 Dec 2006 · 7,104 accessesView PDFCite