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Research ArticleOpen accessIn the abstractCell-Based Therapies in the Prevention of Solid Organ Transplant RejectionAdrian E. Morelli, Sherrie J. DivitoProblem statement: Organ transplantation is a life-saving and increasingly common procedure, as it often serves as the only treatment available for end-stage organ disease. Although the constant development of new and more effective immunosuppressive drugs has revolutionized the prevention and treatment of acute graft rejection, these drugs have significant toxicity, greatly increase patient susceptibility to neoplasms and infection and exert … …American Journal of Immunology, Vol. 8, Issue 2 · 26 Jul 2012 · 7,418 accessesView PDFCite
Research ArticleOpen accessIn the abstractProperties of Chitosan Nanoparticles Formed Using Sulfate Anions as Crosslinking BridgesMayyas M.A. Al-RemawiProblem statement: The preparation of new simple Chitosan nanoparticle delivery system is very important and could have many applications particularly in pharmaceutical field to be used as a drug delivery system. In this study, the production of robust Chitosan nanoparticles has been developed and characterized by chemical crosslinking using sulfate anions. Approach: Chitosan polymer is considered one of the best … …American Journal of Applied Sciences, Vol. 9, Issue 7 · 28 May 2012 · 9,878 accessesView PDFCite
Research ArticleOpen accessIn the abstractDiscovery of Evolutionary Divergence of Biological Nitrogen Fixation and Photosynthesis: Fine Tuning of Biogenesis of the NifH and the ChlL by a Peptidyl-Prolyl Cis/Trans IsomeraseNara Gavini, Sinny Delacroix, Kelvin Harris Jr., Lakshmi PulakatProblem statement: Despite the structural and functional similarities between the nitrogenase that performs biological nitrogen fixation reaction and the Dark Protochlorphyllide Oxidoreductase (DPOR) that performs chlorophyll-biosynthesis, attempts to substitute nitrogenase-components with DPOR-components have hitherto failed. This investigation was undertaken to test if Chlamydomonas reinhardtii protochlorophyllide (Pchlide) reductase (ChlL) that shares some structural similarity with Nitrogenase Reductase (NifH) could complement the … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 4 · 17 Feb 2012 · 7,620 accessesView PDFCite
Research ArticleOpen accessIn the abstractNutritional Supplements and its Effect on Quality of Life and SleepSara Sarrafi Zadeh, Khyrunnisa BegumProblem statement: Inadequate sleep has been recognized as a risk factor for poor health status. Mental stress, body pains, melatonin deficiency, late night awakening disturbing the body clock are triggers for poor quality of sleep and fatigue. Fatigue due to insomnia is a major cause for poor quality of life. Evidences suggest certain nutrients to exert profound influence on quality … …Current Research in Medicine, Vol. 2, Issue 2 · 1 Dec 2011 · 9,260 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Body Calming and Body Vitalizing Effects of Vernonia Amygdalina Leaf Extract and Leaf Powder and their MechanismsUtoh-Nedosa Uchechukwu AnastasiaProblem statement: Vernonia amygdalina (V. amygdalina) leaf soup is regarded by the indigenous Igbo people of South Eastern Nigeria as their best leafy vegetable soup. Despite the bitterness of the bitter leaf soup, the native eaters of the soup feel very content when they eat pounded carbohydrate foods with it. Oral V. amygdalina leaf extract was taken methodically in this … …American Journal of Agricultural and Biological Sciences, Vol. 6, Issue 3 · 20 Sep 2011 · 8,165 accessesView PDFCite
Research ArticleOpen accessIn the abstractGenomic Distance between Thymidylate Synthase and Dihydrofolate Reductase Genes Does Not Correlate With Phylogenetic Evolution in BacteriaVitor Hugo MoreauProblem statement: Dihydrofolate Reductase (DHFR) and Thymidylate Synthase (TS) exist as bifunctional enzymes coded into unique polypeptide chain in protozoans. Bifunctional DHFR-TS is associated with an increase in the enzymatic activity by channeling the substrate between the active sites. In some bacteria, DHFR and TS genes are neighbors in the genome, whereas in others, they are located millions of base … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 1 · 31 Mar 2010 · 8,196 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Environmental Comfort Factors in Enclosed Transitional Space toward Work ProductivityQi Jie Kwong, Nor Mariah Adam, Sai Hong TangProblem statement: The investigated area in this study was the enclosed lift lobby, which distinguishes itself as a unique form of region categorized under building transitional spaces. Such region may act upon on the work performance of occupants, as occupants are sensitive towards the conditions of immediate surroundings. The objective of this study was to investigate the occupants’ perceptions of … …American Journal of Environmental Sciences, Vol. 5, Issue 3 · 30 Jun 2009 · 7,327 accessesView PDFCite
Research ArticleOpen accessIn the abstractDegradative Plasmid and Heavy Metal Resistance Plasmid Naturally Coexist in Phenol and Cyanide Assimilating BacteriaBahig El. Deeb, Abdullah D. AltalhiProblem statement: Heavy metals are known to be powerful inhibitors of xenobiotics biodegradation activities. Alleviation the inhibitory effect of these metals on the phenol biodegradation activities in presence of heavy metals resistant plasmid was investigated. Approach: Combination of genetic systems of degradation of xenobiotic compound and heavy metal resistance was one of the approaches to the creation of polyfunctional strains … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 2 · 30 Jun 2009 · 11,989 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Converting Secondary Forest on Tropical Peat Soil to Oil Palm Plantation on Carbon StorageCh’ng Huck Ywih, Osumanu Haruna Ahmed, Nik Muhamad Ab. Majid, Mohamadu Boyie JallohProblem statement: Peat has been identified as one of the major groups of soils found in Malaysia. Sarawak as the largest state in Malaysia has the biggest reserve of peat-land. There are about 1.5 million ha of peat-land in Sarawak, which are relatively under developed. As is the case with any plant, oil palm trees do sequester carbon as they … …American Journal of Agricultural and Biological Sciences, Vol. 4, Issue 2 · 30 Jun 2009 · 9,048 accessesView PDFCite
Research ArticleOpen accessIn the abstractA case study on Journalistic Coverage for Chinese issues in Saudi NewspapersYahya SharahiliAs Journalism could instinctively exert some effects on international relationships; the importance is how to effectively journalism captures attention. This paper, from the perspective of Saudi-China relationship, chose two renowned Saudi newspapers 'AL RIYADH' and 'AL WATAN', as objective samples. Deductive and descriptive methodologies have been applied to a detailed study on the coverage of Chinese issues in Saudi newspapers … …Journal of Social Sciences, Vol. 4, Issue 1 · 31 Mar 2008 · 7,465 accessesView PDFCite