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Research ArticleOpen accessIn the abstractDigital High-Pass Filters with Milder High-Pass Effect on Digital ImagesIssa A. Al-ShakhrahImage filtering consists of modifying the original image by logically "reimaging" it with a mathematical imaging device in which spatial response can be controlled by the user. Image filtering is performed by a mathematical operation called convolution, which is simply the successive replacement of each point in the original image by a new value produced by a weighted combination of … …American Journal of Engineering and Applied Sciences, Vol. 8, Issue 3 · 11 Jun 2015 · 7,956 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnticancer Activity of Isolated Chemical Constituents from Miliusa smithiaeChonthicha Naphong, Wilart Pompimon, Punchavee SombutsiriMiliusa plants belonging to the family Annonaceae are found in Thailand and have been used as Thai traditional medicines. There have been a few previously reports on the chemical constituents of plants in this genus, describing the presence of aporphine alkaloids, terpenoids, flavonoids, phenylpropanoids, styrylpyrones, bis-styryls and homogentisic acid derivatives. Miliusa smithiae, a new species for Thailand and world, has … …American Journal of Applied Sciences, Vol. 10, Issue 8 · 24 Jul 2013 · 7,263 accessesView PDFCite
Research ArticleOpen accessIn the abstractDesign, Synthesis, Biological Screening and Structure Activity Relationship Study of 4, 6-Dimethyl-2-(Substituted) Mercapto-3-(Substituted) Pyridines as Anti Tubercular AgentsMehul M. Patel, Mahesh T. ChhabriyaProblem statement: Tuberculosis is a leading global mortality factor which has not been effectively controlled, with 1.7 million deaths per year and 8.9 million new cases. Aerobic microbe Mycobacterium tuberculosis H37Rv (MTB) is the causative agent of tuberculosis. Although many active antitubercular agents have since been developed, drug resistance will continue to be a problem. Therefore, there is a clear … …American Journal of Infectious Diseases, Vol. 7, Issue 3 · 3 Nov 2011 · 7,432 accessesView PDFCite
Research ArticleOpen accessIn the abstractEstimating the Parameters of the Negative-Lindley Distribution using Broyden-Fletcher-Goldfarb-ShannoNaushad Mamode KhanProblem statement: The Maximum Likelihood Estimation (MLE) technique is the most efficient statistical approach to estimate parameters in a cross-sectional model. Often, MLE gives rise to a set of non-linear systems of equations that need to be solved iteratively using the Newton-Raphson technique. However, in some situations such as in the Negative-Lindley distribution where it involves more than one unknown … …Journal of Mathematics and Statistics, Vol. 7, Issue 1 · 29 Jan 2011 · 7,381 accessesView PDFCite
Research ArticleOpen accessIn the abstractQuercetin, Quercetrin Except Rutin Potentially Increased Pirarubicin Cytotoxicity by Non-Competitively Inhibiting the P-Glycoprotein-and MRP1 Function in Living K562/adr and GLC4/adr CellsWinit Choiprasert, Nathupakorn Dechsupa, Suchart Kothan et al.Problem statement: Quercetin and its glycoside derivatives are increasingly receiving interests as new generation of anticancer molecules and were recognized by multidrug resistant transporters such as P-glycoprotein and MRP1 protein. Of relevance to their use as anticancer agents alone or in combination with other agents, this study aims to analyze the interaction of the compounds with the MDR transporters including … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 1 · 31 Mar 2010 · 9,673 accessesView PDFCite
Research ArticleOpen accessIn the abstractNew Mesogenic Schiff Base Esters with Polar Chloro Substituent: Synthesis, Thermotropic Properties and X-Ray Diffraction StudiesSie-Tiong Ha, Lay-Khoon Ong, Yasodha Sivasothy et al.Problem statement: Many studies have been conducted on the Schiff base’s alkyl and alkyloxy possessing terminal halogen substituent. However, the thermotropic properties of Schiff base’s ester (or alkanoyloxy) with chloro terminal group remained unstudied. Approach: Synthesis a series of new Schiff base ester possessing polar chloro group and investigate its mesomorphic properties. The title compounds were prepared via condensation and … …American Journal of Applied Sciences, Vol. 7, Issue 2 · 28 Feb 2010 · 12,958 accessesView PDFCite
Research ArticleOpen accessIn the abstractOn Strongly Coupled Linear Elliptic Systems with Application to Otolith Membrane DistortionI.K. YoussefProblem Statement: In this research, the author discussed the problems associated with the approximation of the mixed derivative terms appearing in strongly coupled linear elliptic systems by the finite difference method over irregular domains. To avoid the appearance of mixed derivative terms the author introduced a reformulation for the system through introducing a new dependent variable which adds one supplementary … …Journal of Mathematics and Statistics, Vol. 4, Issue 4 · 31 Dec 2008 · 6,718 accessesView PDFCite
Research ArticleOpen accessIn the abstractNa,K-ATPase α Subunit-like Immunoreactive Proteins in Human Body FluidsJeng-Hsiung F. PengNa,K-ATPase was recently considered a target for breast cancer treatment since its potent inhibitors ouabain and related digitalis compounds that were reported circulating in body fluids before, were found to possess potent anti-breast cancer activity. Based on this finding, it is hypothesized that Na,K-ATPase derivatives could be circulating in the body and potential candidate biomarkers for early disease detection. Western … …American Journal of Immunology, Vol. 2, Issue 1 · 31 Mar 2006 · 6,893 accessesView PDFCite
Research ArticleOpen accessIn the abstractNonlinear Growth Models for Modeling Oil Palm Yield GrowthAzme Khamis, Zuhaimy Ismail, khalid Haron, Ahmad Tarmizi MohammedThis study provided the basic needs of parameters estimation for nonlinear growth model such as partial derivatives of each model, determination of initial values for each parameter and statistical tests of industrial usage. Twelve nonlinear growth models and its partial derivatives for oil palm yield growth are presented in this study. The parameters are estimated using the Marquardt iterative method … …Journal of Mathematics and Statistics, Vol. 1, Issue 3 · 30 Sep 2005 · 15,113 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunological Response of Albino Rats Immunized with UV-Killed Candida albicansAhmad Ibrahim, Yahaya Abdullahi Umar, Mohammed Shehu BusuThe treatments of systemic candidiasis in humans with the current antifungal drugs of choice such as azole derivatives and amphotericin B have raised issues of toxicity and resistance among others. The immunogenic property of killed C. albicans was explored to evoke immunological response in the possible prevention of candidemia. Rats were immunized after acclimatization on two occasions with 106 cells/ml … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 3 · 26 Jul 2019 · 7,716 accessesView PDFCite