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Research ArticleOpen accessIn the abstractPROBABLE CREUTZFELDT JAKOB DISEASE: CASE REPORTYanes Brum Bello, Alexandre Cossenza Pettezzoni De Almeida, Daniela Mendonca Sueth et al.Prion diseases are associated with the accumulation of an abnormal isoformof cellular prion protein (PrPSc), which is the principal constituent of prions. Prions replicate in lymphoreticular tissues before neuroinvasion, suggesting that lymphoreticular biopsy samples may allow early diagnosis by detection of PrPSc. Creutzfeldt-Jakob Disease (CJD) is the most frequent prion disease in humans. Clinical diagnosis of sporadic (CJD) is based … …Current Research in Medicine, Vol. 5, Issue 1 · 14 Mar 2014 · 8,135 accessesView PDFCite
Research ArticleOpen accessIn the abstractClinical and Sociodemographic Risk Factors for Tuberculosis in Human Immunodeficiency Virus Infected PatientsPaz-Ayar Nibardo, Jose Antonio Mata-Marin, Jesus Gaytan-Martinez et al.To identify clinical and sociodemographic factors associated with the risk of tuberculosis in HIV-infected patients. A case-control study in a cohort of HIV-infected patients. Cases: patients coinfected with HIV and pulmonary or extrapulmonary tuberculosis. Controls: no clinical tuberculosis and PPD negative, matched for age and sex. Primary data were obtained from medical records and personal interviews. We identified 47 cases … …American Journal of Infectious Diseases, Vol. 9, Issue 4 · 30 Nov 2013 · 8,239 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntibiotic Usage in Intensive Care Units of Tabriz Imam Reza Hospital, 2011Sepehr Taghizadeh, Mehdi Haghdoost, Omid Mashrabi, Zahra ZeynalikhasraghiDrug therapy is one of the most important factors in providing community health. In a proper selection of an antibiotic for curing an infection, the kind of infective agent and its sensitivity to the utilized drugs must be regarded. The patients whom are admitted in ICUs are 5 to 7 folds more vulnerable to infection. The studies has been done … …American Journal of Infectious Diseases, Vol. 9, Issue 4 · 22 Nov 2013 · 7,722 accessesView PDFCite
Research ArticleOpen accessIn the abstractSalinomycin Toxicosis in Broiler Breeders and Turkeys: Report of the First CaseKonstantinos C. Koutoulis, George Kefalas, Evangelos MinosThe objective of this study was to describe two clinical cases of toxicosis by accidental administration of salinomycin in feed in broiler breeders and turkeys. In the first clinical case, a 32000 broiler breeders flock, 30 weeks of age, suffered a severe mortality during the first week, a sharp decrease in egg production and a dramatic reduction in food consumption … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 4 · 26 Sep 2013 · 8,082 accessesView PDFCite
Research ArticleOpen accessIn the abstractU.S. Malpractice in Internal Medicine: Closed Claim Cases as Tools for Identification, Teaching and PreventionKimberly Ku, Theresa Vettese, Diane LevineMedical malpractice litigation as a system in the U.S. serves multiple goals, including the promotion of safer medicine and the compensation of wrongfully injured patients. However, these aims are often at odds with systems-oriented strategies needed to promote patient safety. Additionally, there is widespread doubt of the actual fairness and efficiency of malpractice litigation. Regardless of the details surrounding major … …Current Research in Medicine, Vol. 4, Issue 2 · 4 Sep 2013 · 6,991 accessesView PDFCite
Research ArticleOpen accessIn the abstractTherapeutic Effects of Highly Purified De-Glycosylated Gcmaf in the Immunotherapy of Patients with Chronic DiseasesLynda Thyer, Emma Ward, Rodney Smith et al.The de-Glycosylated vitamin D binding protein is a powerful Macrophage Activating Factor (GcMAF) that shows multiple biological effects that could be exploited in the immunotherapy of tumours, viral infections and autism. Here we report the observation of a series of clinical cases describing the results obtained administering highly purified GcMAF to patients with diverse types of chronic diseases. These are … …American Journal of Immunology, Vol. 9, Issue 3 · 20 Aug 2013 · 11,868 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssociation of Polymorphism in Growth and Differentiation Factor 5 Gene with Osteoarthritis KneeAbhishek Mishra, Divya Sanghi, Amar Chandra Sharma et al.The present study investigated to identify the association of polymorphism in GDF-5 gene with osteoarthritis in North Indian population. In a case-control study, 300 cases with knee osteoarthritis and an equal number of age and gender matched healthy controls were included. Cases were diagnosed using the ACR Guidelines of Knee Osteoarthritis (KOA). Clinical symptoms were assessed with the knee specific … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 1 · 18 Mar 2013 · 9,422 accessesView PDFCite
Research ArticleOpen accessIn the abstractTuberculoma and Meningitis in a Young Girl: A Case ReportBehroz Ahssan, Shahla AfrasiabianBecause of difficulty in early diagnosis and severe consequences of delay in diagnosis and treatment, tuberculosis meningitis is a serious problem for clinicians. Therefore recognizing rare cases of tuberculosis can improve clinician practice and save patients life in countries with high burden of disease. An 18-year-old girl suffered from fever, headache, illness, arthralgia, myalgia, constipation and weight loss for several … …American Journal of Infectious Diseases, Vol. 8, Issue 2 · 21 May 2012 · 7,692 accessesView PDFCite
Research ArticleOpen accessIn the abstractClinical and Functional Profile of Amyotrophic Lateral Sclerosis Patients: A One Year Follow UpMarco Orsini, Marcos R.G. de Freitas, Osvaldo J.M. Nascimento et al.Problem statement: Amyotrophic Lateral Sclerosis (ALS) is a progressive and degenerative disease that affects the anterior horn motor neurons of the spinal cord and pyramidal tracts. In Brazil, there are few epidemiological data on this disease. Recently, some important findings have been reported, allowing a better understanding on the underlying processes of neuronal death, as well as the characteristics of … …Neuroscience International, Vol. 2, Issue 1 · 6 Oct 2011 · 7,777 accessesView PDFCite
Research ArticleOpen accessIn the abstractCerebrospinal Fluid (CSF) Ferritin for Differentiation of Aseptic and Bacterial Meningitis in AdultsZhinous Bayat Makoo, Nagmeh Ahadi, Akbar Hasani et al.Problem statement: Bacterial meningitis is one of the most important causes of mortality and morbidity. Rapid diagnosis of bacterial cause is very important and critical, because early antibiotic therapy prevents complications; different tests have been developed for rapid diagnosis of bacterial meningitis. One of them is CSF ferritin, which is evaluated in this study. Approach: During cross sectional study from … …American Journal of Infectious Diseases, Vol. 6, Issue 4 · 31 Dec 2010 · 8,049 accessesView PDFCite