Author

Jintanaporn Wattanathorn

Department of Physiology, Faculty of Medicine, Khon Kaen University, Thailand

37 articles in our journals

Articles where this person is an author, newest first. People are matched by their name as printed (no ORCID iD is recorded for them), not by name alone; search the name as text to find namesakes too.

Research ArticleOpen accessNasal Administration of Quercetin Liposomes Improves Memory Impairment and Neurodegeneration in Animal Model of Alzheimer's DiseaseTerdthai Tong-un, Supaporn Muchimapura, Jintanaporn Wattanathorn, Wathita PhachonpaiProblem statement: At present, the development of protective strategy against Alzheimer’s Disease (AD) is increasing its importance due to the high prevalence of AD, a limitation of therapeutic efficacy and its high impacts on economic and social aspects. The development of the preventive and therapeutic strategy to protect against the path physiology induced by free radicals in AD from antioxidant … …American Journal of Agricultural and Biological Sciences, Vol. 5, Issue 3 · 30 Sep 2010 · 7,743 accessesView PDF Cite

Research ArticleOpen accessEffects of Quercetin Encapsulated Liposomes via Nasal Administration: A Novel Cognitive EnhancerTerdthai Tong-un, Supaporn Muchimapura, Wathita Phachonpai, Jintanaporn WattanathornProblem statement: Demand for cognitive-enhancing drugs is growing. Numerous medicinal plants possessing antioxidant activity have received much attention as food supplement to improve cognitive function. Quercetin is a potent free radical scavenger and antioxidant. However, the limitations of quercetin: Rapidly metabolized is an obstacle to its use for a cognitive enhancer. In addition, the burden of blood brain barrier can … …American Journal of Applied Sciences, Vol. 7, Issue 7 · 31 Jul 2010 · 7,498 accessesView PDF Cite

Research ArticleOpen accessQuercetin Liposomes via Nasal Administration Reduce Anxiety and Depression-Like Behaviors and Enhance Cognitive Performances in RatsTerdthai Tong-Un, Panakaporn Wannanon, Jintanaporn Wattanathorn, Wathita PhachonpaiProblem statement: At present, the prevalence of neuropsychological disorders particularly anxiety, depression and dementia are increase. Many strategies have been developed in order to increase the efficiency of treatment and decrease side effects. Oxidative stress has been reported to play an important role on various path physiological states. Quercetin is a flavonoid commonly found in fruits and vegetables. It has … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 2 · 30 Jun 2010 · 9,034 accessesView PDF Cite

Research ArticleOpen accessNasal Administration of Quercetin Liposomes Modulate Cognitive Impairment and Inhibit Acetylcholinesterase Activity in HippocampusTerdthai Tong-Un, Supaporn Muchimapura, Wathita Phachonpai, Jintanaporn WattanathornProblem statement: Oxidative stress is a major factor implicated in the degeneration of cholinergic neurons in Alzheimer’s Disease (AD). Several reports have indicated that antioxidant intake is beneficial to delay or inhibit the progression of this disease. Presently, Acetylcholinesterase (AChE) inhibitors are the mainstay of therapy for AD. Quercetin, one of the flavonoids in fruits and vegetables, has a powerful … …Neuroscience International, Vol. 1, Issue 1 · 30 Jun 2010 · 7,170 accessesView PDF Cite

Research ArticleOpen accessPorcine Brain Extract Attenuates Memory Impairments Induced by Focal Cerebral IschemiaJinatta Jittiwat, Jintanaporn Wattanathorn, Terdthai Tongun et al.Problem statement: Stroke or cerebral ischemia has been recognized as one important problem worldwide. To date, the effectiveness of protective and therapeutic strategies against stroke is still very limited. Therefore, the development of novel strategy is required. Porcine brain is traditional believed to improve brain functions. Recent studies showed that the extract of porcine brain could protect against brain damage … …American Journal of Applied Sciences, Vol. 6, Issue 9 · 30 Sep 2009 · 14,615 accessesView PDF Cite

Research ArticleOpen accessEvaluation of the Anxiolytic and Antidepressant Effects of Alcoholic Extract of Kaempferia parviflora in Aged RatsJintanaporn Wattanathorn, Prasert Pangpookiew, Kittisak Sripanidkulchai et al.To date, the search for novel pharmacotherapy from medicinal plants for psychiatric illnesses has significantly progressed. The present study was performed to evaluate the anxiolytic and antidepressant like activities of the K.parviflora rhizome extract. Aged male Wistar rats were orally administered the alcoholic extract of this plant at various doses ranging from 100, 200 and 300 mg kg-1 BW once … …American Journal of Agricultural and Biological Sciences, Vol. 2, Issue 2 · 30 Jun 2007 · 9,971 accessesView PDF Cite

Research ArticleOpen accessIntranasal Administration of Quercetin Liposome Decreases Anxiety-like Behavior and Increases Spatial MemoryJintanaporn Wattanathorn, Wathita Phachonpai, Aroonsri Priprem, Saengrawee SuthiparinyanontAt present, the effects of quercetin liposome on anxiolytic activity and cognitive function are unclearly known. In this study, male Wistar rats were administered quercetin liposome via intranasal route once daily continually for 4 weeks. The anxiolytic activity and cognitive enhancing effect were determined after single administration, 1, 2, 3 and 4 weeks of treatment using elevated plus maze test … …American Journal of Agricultural and Biological Sciences, Vol. 2, Issue 1 · 31 Mar 2007 · 9,091 accessesView PDF Cite