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206 results for “Tissues”
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Research ArticleOpen accessIn the abstractEvaluation of Acute Oral Toxicity Induced by Tablets Based on Ethanolic Extract of Salvia dumetorum Leaves in Experimental RatsYana Levaya, Karakoz Badekova, Mussa Zholdasbayev, Gayane AtazhanovaThe aim of this study was to assess the acute oral toxicity of a solid dosage form based on Salvia dumetorum Andrz. ex Besser leaf extract (SDT5) in experimental rats. Acute toxicity was evaluated over a 14-day observation period following a single oral administration at three dose levels (500 mg/kg, 1000 mg/kg, and 2000 mg/kg), prepared in 0.5 mL of … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 23 Jun 2026 · 1,245 accessesView PDFCite
Case SeriesOpen accessIn the abstractSurge of Mucormycosis in the Jaws Among COVID-19 Patients: A Case Series Highlighting the Role of Diabetes and ImmunosuppressionRam Mohan, Dharnappa Poojary, Sreehari Sreedhar et al.Mucormycosis is a life-threatening fungal infection caused by Mucorales species, frequently occurring in immunocompromised patients. This case series investigates the alarming rise in maxillary mucormycosis among post-COVID-19 patients in India and explores its correlation with uncontrolled diabetes and immunosuppressive conditions. This case series analyzed 52 patients, primarily with maxillary infections, to identify the association between COVID-19 and mucormycosis. Diagnostic methods … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 13 Apr 2026 · 1,355 accessesView PDFCite
Research ArticleOpen accessIn the abstractCascaded MNetV3UNet: A Lightweight Two-Stage Architecture for High-Precision Brain Tumor Segmentation in MRIMayuri Popat, Sanskruti PatelPrecise brain tumor segmentation is an essential but quite challenging process in MRI images because of their irregular shapes, heterogeneous appearance, and low contrast with surrounding tissues. While U-Net-based architectures have achieved significant success, their high computational complexity limits deployment on resource-constrained systems. In this study, a Novel two-stage cascaded architecture, MNetV3UNet, is introduced, which employs the light-weight MobileNetV3-Large as … …Journal of Computer Science, Vol. 22, Issue 2 · 23 Feb 2026 · 1,793 accessesView PDFCite
Research ArticleOpen accessIn the abstractMorphological Changes in Brain Tissue During Experimental HypoxiaAizhan Mussayeva, Ulbossin Kozhaniyazova, Laura Koibasova et al.The extensive application of hypoxic training to enhance cerebral circulation highlights its significant role in effectively realizing the therapeutic and health-promoting benefits of this method. The discrepancy between the data on the features of cerebral circulation and cellular metabolism in brain tissues during circulatory hypoxia and significant interest in the physiological patterns of the integrative response of the body determined … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 20 Feb 2026 · 1,555 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Fertilization Frequency and Amount on the Chemometric Characteristics, Physiology, and Yield of Tomato Under Substrate CultivationEnling Ji, Qianqian Di, Qingjie Du et al.This study examined the effects of fertilization frequency and quantity on growth, yield, and quality of tomatoes under substrate cultivation. A factorial experiment evaluated two fertilization frequencies (every 5 or 10 days) and three fertilization levels (15.69, 31.38, or 62.76 kg·ha⁻¹), along with an unfertilized control. Plants were assessed for growth and development, photosynthetic pigment content, gas exchange parameters, nutrient … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 16 Feb 2026 · 1,718 accessesView PDFCite
Research ArticleOpen accessIn the abstractEpigenetic Regulation of Extracellular Matrix Remodeling in Skin Aging: Mechanisms and InteractionsJiguang Yang, Yusong Shi, Xiaoqing YanSkin aging results from complex interactions between genetic factors, environmental stressors, and epigenetic modifications that regulate extracellular matrix (ECM) remodeling. Accumulation of senescent cells impairs tissue regeneration through mechanisms including telomere shortening, reactive oxygen species accumulation, and ultraviolet (UV) radiation exposure. While epigenetic pathways regulate skin homeostasis, regeneration, and senescence, the specific epigenetic changes occurring during UV exposure, chronological aging, … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 15 Feb 2026 · 1,461 accessesView PDFCite
Research ArticleOpen accessIn the abstractRelative Transcription Expression Level of SIRT1, SIRT2 and SIRT3 in Correlation to the Expression of a Set of Selected Cancer Related Genes in Human Breast CancerHamdy Swelim, Omnia Mansour, Salah Abdel-Rahman et al.Mammalian Sirtuins have been shown to perform distinct cellular functions and deregulated expression of these genes was reported to be involved in the development of various malignancies including breast cancer. An increasing number of evidence indicates that Sirtuins have both tumor promoter and tumor suppressor functions. However, the roles of Sirtuins have not been well-studied in breast cancer. In the … …OnLine Journal of Biological Sciences, Vol. 18, Issue 2 · 18 Jan 2018 · 7,479 accessesView PDFCite
Review ArticleOpen accessIn the abstractFrom Health to Disease: Functional Insights of Scavenger Receptor Class B Type I in Lipid Metabolism and Disease PathogenesisSujina Simon Sailet, Poornima Ajay Manjrekar, Santosh Rai et al.Scavenger receptor class B type I (SR-B1) has caught considerable interest among the scientific community due to its pivotal role in several biological and pathological processes. It is a multifunctional integral membrane protein and multiligand receptor encoded by the SCARB1 gene. SR-B1 has a wide distribution, primarily in the liver as well as steroidogenic organs including the gonads and adrenal … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 11 Jul 2025 · 3,672 accessesView PDFCite
Research ArticleOpen accessIn the abstractStudy of the Anatomical, Morphological, and Phytochemical Properties of Conium maculatum L.Aigerim Abdygalieva, Meruyert Sakenovna Kurmanbayeva, Dina Karabalayeva et al.The aim of this study is to identify the characteristic anatomical and morphological features and analyze the phytochemical composition of Conium maculatum L. growing in the Almaty region, in order to assess the quality of the medicinal plant raw material. Detailed anatomical investigations were conducted, including microscopy of various plant organs (leaves, stems, and roots), as well as phytochemical analysis … …OnLine Journal of Biological Sciences, Vol. 25, Issue 2 · 23 Jun 2025 · 3,411 accessesView PDFCite
Literature ReviewOpen accessIn the abstractControl of Contamination of Tissue Plant Cultures During in Vitro Clonal MicropropagationIrina Anikina, Nursultan Kaynidenov, Dora Dayu Rahma Turista et al.Plant micropropagation is currently an important method for modern large-scale propagation of valuable plant crops. Among the risks limiting the success of this method is the contamination of cultured plants. Conventional surface sterilization methods are not always effective against internal infection of plant tissues, and secondary contamination of tissue cultures during replication is also a major problem. This causes scientific … …OnLine Journal of Biological Sciences, Vol. 25, Issue 2 · 8 Apr 2025 · 8,714 accessesView PDFCite