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32 results for “Therapeutic Strategies”

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Research ArticleOpen accessIn the abstractNeuropsychological Consequences of HIV and Drug AuseArun Venkatesan, Ola Selnes, Valerie Wojna et al.Accurate assessment of the functional consequences of human immunodeficiency virus (HIV) infection and drugs of abuse are critical as large populations are afflicted with both. Both are interdependent epidemics with important socioeconomic consequences. Experimental studies in animal models and in vitro clearly indicate that HIV and drugs of abuse cause increased neurodegeneration, glial cell activation and enhanced HIV replication. Nevertheless, … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 6,662 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunohistochemical Detection of Apoptosis-Related Proteins in Gerbil Hippocampus Transient Cerebral Ischemia: Neuroprotective Effect of PitavastatinToshiki Himeda, Natsumi Hayakawa, Hiroko Tounai et al.Delayed and selective neuronal damage was caused in the CA1 sector of hippocampus following 5 min of transient cerebral ischemia in gerbils. We investigated the immunohistochemical alterations of apoptosis-related proteins such as bcl-2α, bcl-xs/l, bax, cytochrome c, and active caspase 3 and TUNEL staining in the hippocampus at 1 and 5 hr and 1, 2, 5 and 14 days after … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 4 · 31 Dec 2005 · 6,271 accessesView PDFCite