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549 results for “Structural”
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Review ArticleOpen accessEvery word in the titleStructural Barriers to the Deployment of AI Foundation ModelsHristo Hristov, Elena Somova, Emil FuchedzhievArtificial Intelligence (AI) foundation models excel at benchmarks but are not always cost-effective or successfully deployed in enterprise systems. This paper analyzes the failures in their deployment through interconnected structural components characterized by: Economic constraints (computational costs, memory, and latency that scale with increasing use of AI model services), cognitive constraints (related to training objectives that optimize plausibility rather than … …Journal of Computer Science, Vol. 22, Issue 10 · 5 Oct 2026 · 808 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleIn silico and in vitro Structural Analysis on the Interaction of Calmodulin and Calmodulin-Binding Motif of FKBP35 from Plasmodium knowlesiSazlinawatie Aladin, Cahyo Budiman et al.FK506-binding protein 35 (FKBP35) is a peptidyl-prolyl cis-trans isomerase found in Plasmodium knowlesi, a zoonotic malaria parasite responsible for concerning cases of malaria infection in East Malaysia. This protein contains a segment known as the calmodulin-binding motif (Pk-CBM), which is predicted to facilitate interaction with calmodulin from P. knowlesi (Pk-CaM). Although this interaction is considered promising for future antimalarial drug … …OnLine Journal of Biological Sciences, Vol. 25, Issue 2 · 10 Mar 2025 · 4,846 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThermodynamic Inference of the Antioxidant Process of Malic Acid and Its Structural AnalogsHan Wu, Wenhao Dong et al.Two structural analogs of Malic Acid (MA), 2-isopropylmalic Acid (2-IPMA), and 3-isopropylmalic Acid (3-IPMA) were recently identified and separated from wine. Although they have been shown to have antioxidant activity, the mechanism of their actions is still unclear. Antioxidant activities of 2-IPMA and MA were tested through DPPH, ABTS, and PTIO methods and the antioxidant-related thermodynamic properties were evaluated using … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 4 · 30 Oct 2024 · 4,824 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEvolutionary Structural Optimization of Wind Bracing Connection Plates in Steel StructuresReza Kasiri, Saeid Eslamian, Theodore C. Crusberg et al.Evolutionary Structural Optimization (ESO) is one of the rules in structural engineering which has received much attention by the researchers. Today, the reduction of construction cost and weight is an important issue in the structure design. The optimization phenomenon is pursuing to fulfill this objective. Thus, presenting a design which could be both safe and economic is of special significance. … …American Journal of Engineering and Applied Sciences, Vol. 13, Issue 3 · 15 Jul 2020 · 6,968 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleBasis of Guidelines for Structural Design and Thermal Assessment of Buildings with Hybrid CLT-Glass ElementsNikola Perković, Vlatka Rajčić, Chiara Bedon et al.Facade elements are known to represent a building component with multiple performance parameters to satisfy. Among others, “advanced facades” take advantage from hybrid solutions, like the assemblage of laminated materials. In addition to enhanced mechanical properties that are typical of optimally composed hybrid structural components, these systems are energy efficient, durable and offer lightening comfort and optimal thermal performance. This … …International Journal of Structural Glass and Advanced Materials Research, Vol. 4, Issue 1 · 9 Apr 2020 · 6,969 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleStructural and Substrate Interaction Properties of Alkaline Phosphatase from Paenibacillus sp. PSB04: In-Silico AnalysisHerman Umbau Lindang, Cahyo BudimanA Phosphate-Solubilising Bacterium (PSB) of Paenibacillus sp. PSB04 was previously isolated from the Sabah tropical rainforest in Malaysia. Interestingly, the genome sequence of the PSB04 strain harbored an Alkaline Phosphatase (AP) (EC 3.1.3.1) gene and was hypothesized to have unique structural characteristics. Therefore, this study aims to determine the AP three-Dimensional (3D) model and catalytic mechanism from Paenibacillus sp. PSB04 … …OnLine Journal of Biological Sciences, Vol. 22, Issue 3 · 16 Jul 2022 · 5,910 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleStructural Analysis of Spatial MechanismsFlorian Ion Tiberiu PetrescuThe paper briefly presents how structural analysis is performed on spatial mechanisms, presenting a practical application in the mechatronics of parallel robots, especially in Steward platforms. Structural analysis always helps to better understand the phenomena and especially the way the mechanisms are made. At spatial mechanisms the problems are a little more complex than those raised by plane mechanisms. For … …American Journal of Engineering and Applied Sciences, Vol. 11, Issue 2 · 26 May 2018 · 7,971 accessesView PDFCite