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32 results for “Sprague Dawley Rat”

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Research ArticleOpen accessIn the abstractEndothelial Dysfunction and Insulin Resistance as Pathophysiologic Mechanisms in a Rat Model of PreeclampsiaAyman Z. Elsamanoudy, Amr M. AbbasProblem statement: To assess the plasma concentrations and placental gene expression of soluble fms like tyrosine kinase (sFlt-1), Vascular Endothelial Growth Factor (VEGF), visfatin and Tumour Necrosis Factor α (TNFα) in a rat model of preeclampsia, induced by chronic Reduction of Uterine Perfusion Pressure (RUPP) and to investigate the involvement of Insulin Resistance (IR) in the pathophysiology of preeclampsia and … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 3 · 30 Sep 2010 · 7,509 accessesView PDFCite
Research ArticleOpen accessIn the abstractGastroprotective Effects of Melastoma malabathricum Aqueous Leaf Extract against Ethanol-Induced Gastric Ulcer Iin RatsFouad Hussain, Mahmood Ameen Abdulla, Suzita Mohd Noor et al.The gastro-protective effects of the aqueous leaf extract of Melastoma malabathricum was investigated against ethanol-induced gastric mucosal injuries in rats. There were four groups of adult sprague dawley rats, consisting of six rats per group. Macroscopically, oral administration of absolute ethanol to rats that had been pre-treated with only distilled water significantly produced extensive lesions of the gastric mucosa. Oral … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 4 · 31 Dec 2008 · 7,780 accessesView PDFCite