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42 articles for “Solubility”
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Research ArticleOpen accessIn the abstractKinetic Optimization of Folic Acid Polymer Conjugates for Drug TargetingJacob M. Ngoy, Sunny E. Iyuke, Clarence S. Yah, Wilhelm E. NeuseProblem statement: Folic Acid (FA) is an essential, bioavailable water soluble B-complex vitamin that helps in the replication of normal cells. It is obtained from natural sources and it deficiency can leads to oncogenic cells development. Within this frame work in mind, we designed and synthesized a new bioconjugate carrier that can enhance the effectiveness of FA. Approach: The polymeric … …American Journal of Applied Sciences, Vol. 8, Issue 6 · 13 Jun 2011 · 7,101 accessesView PDFCite
Research ArticleOpen accessIn the abstractRelation between Macroscopic Binding Constant and the Anticancer Efficacy of the Bovine Serum Albumin-Quercetin Complex against Drug-Sensitive and Drug-Resistant CellsWinit Choiprasert, Chatchanok Loetchutinat, Nathupakorn Dechsupa, Samlee MankhetkornProblem statement: We have previously analyzed the interaction of BSA with flavonoids by using FRET. In this study, the role of BSA on increasing in solubility and on carrying the quercetin derivatives thus enhanced their anticancer efficacy against drug-sensitive and drug-resistant cells were conducted. Approach: The macroscopic (KD) and microscopic (kd) binding constant of the complexation and the cellular partition … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 1 · 27 May 2011 · 8,292 accessesView PDFCite
Research ArticleOpen accessIn the abstractIdentification and Antiproliferative Activity Evaluation of a Series of Triterpenoids Isolated from Flueggea virosa (Roxb. ex Willd.)Sod Monkodkaew, Chatchanok Loetchutinat, Narong Nuntasaen, Wilart PompimonProblem statement: Medicinal plants derived anticancer were now being subjects of many research groups especially, the secondary metabolite triterpenoids trees which had enormous potential to inspire and influence modern antiproliferative research. The study aimed to investigate the chemical constitution and their potential use as antiproliferative activity of purified compounds derived from F. virosa. Approach: The F. virosa was selected and … …American Journal of Applied Sciences, Vol. 6, Issue 10 · 30 Oct 2009 · 7,626 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn vitro Growth and Inhibition Studies of Monosodium Urate Monohydrate Crystals by Different Herbal ExtractsBharat B. Parekh, Sonal R. Vasant, Kashmira P. Tank et al.Problem statement: A large number of people in the world have been suffering from gout for centuries. Gout is the term given to a metabolic condition in which the signs and symptoms results from the deposition of crystals of Monosodium Urate Monohydrate (MSUM) in various connective tissues. Approach: It was quite difficult to grow good quality large MSUM crystals because … …American Journal of Infectious Diseases, Vol. 5, Issue 3 · 30 Sep 2009 · 10,210 accessesView PDFCite
Research ArticleOpen accessIn the abstractBiocontrol of Botrytis allii Munn the Causal Agent of Neck Rot, the Post Harvest Disease in Onion, by use of a New Iranian Isolate of StreptomycesM. Jorjandi, G.H. Shahidi Bonjar, A. Baghizadeh et al.Problem statement: Soil actinomycetes particularly Streptomyces spp. have showed antagonistic activity against wide range of plant pathogens. In the recent decades they have attracted high interests as biocontrol agents. Onion neck rot or gray mold caused by Botrytis allii have imposed economic post harvest damages to onion bulbs and decreased its storage durability and market value. Approach: To investigate for … …American Journal of Agricultural and Biological Sciences, Vol. 4, Issue 1 · 31 Mar 2009 · 9,935 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of the Chemical and Sensory Attributes of Solar and Freeze-Dried Jameed Produced from Cow and Sheep Milk with the Addition of Carrageenan Mix to the Jameed PasteAyman Suliman Mazahreh, Ali Faleh Al-Shawabkeh, Jihad M. QuasemJameed is a fermented dried dairy product in the form of stone hard balls or other shapes produced by straining the heated buttermilk on cloth mesh bags, salting the formed paste by kneading, shaping and drying in the sun. This product is reconstituted after disintegration to be used in the preparation of Mansaf, the national dish in Jordan, which is … …American Journal of Agricultural and Biological Sciences, Vol. 3, Issue 3 · 30 Sep 2008 · 8,176 accessesView PDFCite
Research ArticleOpen accessIn the abstractPhysiochemical Properties of Sago Starch Modified by Acid Treatment in AlcoholP.H. Yiu, S.L. Loh, A. Rajan et al.Sago starch is usually chemically modified to overcome and improve the unstable properties of native sago starch during processing. In this study, sago starch was treated in hydrochloric acid in the presence of methanol, ethanol and 2-propanol at 450C for 1 hour. Granule size, granular structure and solubility of the modified starch were investigated. Results showed that recovery yields of … …American Journal of Applied Sciences, Vol. 5, Issue 4 · 30 Apr 2008 · 8,909 accessesView PDFCite
Research ArticleOpen accessIn the abstractAtomic Absorption Spectrometric Determination of Certain Fluoroquinolones in Pharmaceutical Dosage Forms and in Biological FluidsH. Salem, W. Khater, L. FadaSimple, accurate, sensitive and selective methods are described for the quantitative determination of ten fluoroquinolones (amifloxacin, ciprofloxacin hydrochloride, difloxacin hydrochloride, enoxacin, enrofloxacin, lomefloxacin hydrochloride, levofloxacin, norfloxacin, ofloxacin and pefloxacin mesylate). The methods are based on precipitation of the ion associates formed from the reaction of the cited drugs with silver nitrate, copper acetate and ferric chloride. The formation and solubility … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 2 · 30 Jun 2007 · 7,419 accessesView PDFCite
Research ArticleOpen accessIn the abstractExpression of Thioredoxin-Fusion Proteins of α-Gliadin, γ-Gliadin and Low Molecular Weight Glutenin, from Wheat Endosperm and their Domains in EnterobacteriaClaudia G. Benitez-Cardoza, Yves Popineau, Jacques GueguenWheat seed storage proteins play a determining role in the viscoelastic properties of wheat gluten. The genes encoding α-gliadin, γ-gliadin and Low Molecular Weight glutenin and their N-central-repetitive and C-terminal domains from wheat endosperm had been subcloned into a thioredoxin expression system (pET102/D-Topo) and produced as fusion proteins in E. coli. The expression levels for each of the proteins varied … …American Journal of Infectious Diseases, Vol. 3, Issue 2 · 30 Jun 2007 · 6,746 accessesView PDFCite
Research ArticleOpen accessIn the abstractBiological Activity of Methyl tert-butyl Ether in Relation to Soil Microorganisms has a Negative Environmental ImpactGholam H.S. BonjarFuel oxygenates are added to gasoline to enhance combustion efficiency of automobiles and reduce air pollution. Methyl tert-butyl ether (MTBE) is the most commonly used oxygenate because of its low cost, high-octane level and ease of blending with gasoline. However, due to its water solubility, high mobility and low biodegradability it leaches in soil subsurface at the speed of groundwater. … …American Journal of Environmental Sciences, Vol. 1, Issue 2 · 30 Jun 2005 · 6,661 accessesView PDFCite