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52 articles for “Resistance Genes”
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Research ArticleOpen accessIn the abstractProposal of a Genome Editing System for Genetic Resistance to Tomato Spotted Wilt VirusFederico Martinelli, Giovanni Grillone, Filippo SgroiViruses provoke considerable economical losses in agriculture. New molecular approaches to develop genetic resistance based on translational genomics and precision genetic modifications are highly expected. The type II Clustered, Regularly Interspaced Palindromic Repeats (CRISPR) system including Cas9 nuclease represent a promising and very powerful tool to specifically modulate the expression and activity of genes involved in biotic stress responses. In … …American Journal of Applied Sciences, Vol. 11, Issue 11 · 7 Jan 2015 · 7,685 accessesView PDFCite
EditorialOpen accessIn the abstractANTIBIOTIC RESISTANCE: A FRIGHTENING HEALTH DILEMMARuchi Tiwari, Kuldeep DhamaByarugaba, D.K., 2004. Antimicrobial resistance in developing countries and responsible risk factors. Int. J. Antimicrob. Agents, 24: 105-110. DOI: 10.1016/j.ijantimicag.2004.02.015 Cirz, R.T., J.K. Chin, D.R. Andes, V. de Crécy-Lagard and W.A. Craig et al., 2005. Inhibition of mutation and combating the evolution of antibiotic resistance. PLoS Biol., 3: e176-e176. DOI: 10.1371/journal.pbio.0030176 Dhama, K., S. Chakraborty, Mahima, M.Y. Wani and A.K. … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 3 · 26 Sep 2014 · 10,774 accessesView PDFCite
Research ArticleOpen accessIn the abstractAdiponectin Regulation in Type 2 Diabetic Rats: Effects of Insulin, Metformin and DexamethasoneTamer Ahmed Ismail, Mohamed Mohamed Soliman, Shimaa Ahmed IsmailAdiponectin is a protein synthesized from adipose tissue, increases peripheral glucose utilization in liver and skeletal muscle. Adiponectin expression and secretion are decreased during obesity and insulin resistance. In this study, the effect of insulin, metformin and dexamethasone on serum lipid profiles was examined in Type 2 Diabetic (T2D) rats. T2D was induced by feeding rats a high fat diet … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 4 · 23 Nov 2013 · 7,723 accessesView PDFCite
Research ArticleOpen accessIn the abstractPrevalence of Heterogeneous Glycopeptide Intermediate Resistance in Methicillin-Resistant Staphylococcus aureusManu Chaudhary, Anurag PayasiMultidrug resistant Methicillin-Resistant Staphylococcus Aureus (MRSA) is a major cause of nosocomial and community acquired infections and is on the rise. The aim of this investigation was to explore the prevalence of MRSA and heterogeneous Glycopeptide Intermediate Staphylococcus Aureus (hGISA) in various clinical samples, to investigate the various antibiotic resistant determinant genes among these strains collected from north and west … …American Journal of Infectious Diseases, Vol. 9, Issue 3 · 4 Sep 2013 · 7,202 accessesView PDFCite
Research ArticleOpen accessIn the abstractBioinformatics Analysis of Some Functional Genes and Proteins Involved in Obesity-Induced Type 2 DiabetesEhab M. Abdella, Rasha R. Ahmed, Mohamed B. Ashour et al.The incidence of type-2 diabetes is rising rapidly worldwide, mainly because of the increase in the incidence of obesity, which is an important risk factor for this condition. Both obesity and type-2 diabetes are complex genetic traits but they also share some nongenetic risk factors. Differences among individuals in their susceptibility to both these conditions probably reflect their genetic constitutions. … …Current Research in Bioinformatics, Vol. 1, Issue 2 · 6 May 2013 · 12,601 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntibiotic Resistance in Co-Culture Biofilm of Listeria monocytogenes J0161Prem Saran Tirumalai, Soam PrakashProblem statement: Do naturally group-living bacteria express genes the same way as they do in lab grown pure cultures? An intriguing question. Listeria monocytogenes, a dreaded pathogen has been and continues to be a subject of study with reference to gene expressions. However, all studies concerning the gene expression of L. monocytogenes have been done on pure culture states. Our … …Current Research in Microbiology, Vol. 3, Issue 1 · 29 Mar 2012 · 10,216 accessesView PDFCite
Research ArticleOpen accessIn the abstractStrains of Klebsiella Pneumoniae from Intensive Care Unit Producing CTX-M-15 Extended Spectrum Beta LactamasesI.R. Iroha, A.E. Oji, A.E. Nwakaeze et al.Problem statement: Resistance to third generation cephalosporins due to acquisition and expression of Extended Spectrum β-Lactamase (ESBL) among Gram-negative bacteria is on the increase. Infections involving extended spectrum beta lactamase bacteria are associated with significant morbidity and mortality. Therefore, infections due to ESBL isolates continue to pose a serious challenge to infection management worldwide. Since screening for ESBL is not … …Current Research in Microbiology, Vol. 2, Issue 2 · 6 Mar 2012 · 7,826 accessesView PDFCite
Research ArticleOpen accessIn the abstractImpact of L-Carnitine and Cinnamon on Insulin-Like Growth Factor-1 and Inducible Nitric Oxide Synthase Gene Expression in Heart and Brain of Insulin Resistant RatsMona A. MohamedProblem statement: Evaluate the effects of daily administration of L-carnitine and cinnamon extract for two weeks on the expression of Insulin-like Growth Factor-1 (IGF-1) and inducible Nitric Oxide Synthase (iNOS) genes in cardiac and brain tissues of rats with Insulin Resistance (IR). Approach: Rats were divided into 4 groups (8 animals each): Group (1) rats fed control diet (60% starch) … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 3 · 30 Sep 2010 · 8,740 accessesView PDFCite
Research ArticleOpen accessIn the abstractAmelioration of Inducible Nitric Oxide Synthase, Insulin like Growth Factor-1 Gene Expression and Insulin Receptor Substrate-1 in Liver Tissue of Insulin Resistant Rats Treated With L-CarnitineHala M. GhanemProblem statement: It has been reported that genes expression (inducible Nitric Oxide (iNOS). Insulin-like Growth Factor-1(IGF-1) have a role in both glucose homeostasis and insulin resistance. The aim of this study was designed to evaluate the amelioration of the iNOS, IGF-1 genes expression as well as IRS-1 in liver tissues of rats fed high fructose diet treated with Lcarnitine. Approach: … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 3 · 30 Sep 2010 · 7,264 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Exercise Training on Adiponectin Receptor Expression and Insulin Resistance in Mice Fed a High Fat DietNaglaa Fathy Alhusseini, Nasr Arafat Belacy, Enas Mohammed Kasem, Mona Maher AllamProblem statement: Adiponectin is an adipocyte secreted hormones, exerts its effects via the specific receptors. AdipoR1 and adipoR2 and plays a pivotal role in lipid and glucose metabolism. Approach: We investigated the effect of increased physical activities on insulin resistance and if this effect is modulated through adiponectin receptor expression. Results: We also assessed the effect of High Fat Diet … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 2 · 30 Jun 2010 · 9,951 accessesView PDFCite