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Research ArticleOpen accessIn the abstractProcalcitonin and Clinical Factors Associated with Severe Dengue Infection in Hospitalized Adults in MalaysiaHuzairi Sani, Nada Syazana, Zahir Izuan et al.Dengue Fever (DF) is the commonest mosquito-borne viral infection that results in hospitalisation amongst patients in Malaysia. The cornerstone of managing dengue virus infection is the prediction hence prevention of severe DF from developing. Warning signs proposed by WHO as clinical predictors of severe DF are insensitive. Procalcitonin (PCT) has been shown to increase in bacterial infections and is useful … …American Journal of Infectious Diseases, Vol. 15, Issue 4 · 3 Dec 2019 · 7,362 accessesView PDFCite
Research ArticleOpen accessIn the abstractInvolvement of the α/β Isoform of p38 MAP Kinase in Chemotactic Responses of Human Eosinophils to Eotaxin (CCL11) and RANTES (CCL5)Anwar M Hasan, Gordon DentEosinophils are the principal effector cells for allergic inflammation in a variety of diseases, in which they contribute to tissue damage and remodelling processes via the secretion of cytotoxic granular proteins and cytokines. The intracellular mechanisms that control the activation, recruitment and survival of eosinophils are fundamental in understanding these disease processes. Phosphoinositide 3-kinase (PI3K) has been shown previously to … …American Journal of Immunology, Vol. 13, Issue 4 · 26 Oct 2017 · 7,946 accessesView PDFCite
EditorialOpen accessIn the abstractFocalize the Structure of Myd88 in TLR Signaling Pathway to Modulate Innate Immune Response: New Target for Old DiseasesShuai Xing, Ping ZhouAll diseases have their Achilles’ Heel to target and this is especially true for immunorelated diseases which must be treated by targeting the immune system somewhere and somehow correctly. In the most recent decade, immunologists recognized that the Toll-Like Receptor (TLR) signaling pathway in innate immune system plays a double-edged role in the pathogenesis of many notorious diseases. Although the … …American Journal of Immunology, Vol. 13, Issue 3 · 6 Sep 2017 · 7,865 accessesView PDFCite
InvestigationOpen accessIn the abstractDiabetes Group Visit in a Primary Care SettingSelma Mujezinovic RochesterThe group visits models one innovation in the field of chronic illness management that shows promise in meeting the growing demands for this type of care. Patients get significant peer and healthcare provider support during group visits. Group visits typically last 90 min and occur on a regularly scheduled basis. The study design was a quasi-experimental pre-post-test with a comparison … …International Journal of Research in Nursing, Vol. 7, Issue 2 · 30 Jun 2017 · 7,235 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Randomized Population Constructive Heuristic for the Team Orienteering ProblemManal ZettamThe NP-hard (complete) team orienteering problem is a particular vehicle routing problem with the aim of maximizing the profits gained from visiting control points without exceeding a travel cost limit. The team orienteering problem has a number of applications in several fields such as athlete recruiting, technician routing and tourist trip. Therefore, solving optimally the team orienteering problem would play … …Journal of Computer Science, Vol. 13, Issue 9 · 17 Jun 2017 · 8,290 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Relationship of Parents Knowledge Level and Socioeconomic Factor to Oral Health of Down Syndrome ChildrenYetty Herdiyati, Puspita HajardhiniDifferent conditions of the oral cavity in children with Down syndrome which are compared to children without Down syndrome increase higher parents knowledge and the risk factors in maintaining oral health of children with Down syndrome. Correlation test with descriptive analytic by survey techniques was aimed to know the relationship of parents knowledge level and socioeconomic factor to oral health … …American Journal of Applied Sciences, Vol. 14, Issue 8 · 24 May 2017 · 7,208 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluating the Usability of Model Transformations Testing Approach (MTTA)Lukman Ab. Rahim, Ziyaulhaq Aliyu, Emy E. MustaphaModel Transformation (MT) is a key component in Model Driven Development (MDD). Model transformation is used to transform source model into a target model, improve the model quality and also introduce the design pattern and refactoring. Model transformation are not free from bugs similar to other software development artifacts and it needs to be verified. Code Generators (CG) are a … …Journal of Computer Science, Vol. 13, Issue 1 · 6 Mar 2017 · 7,680 accessesView PDFCite
Research ArticleOpen accessIn the abstractAetiology of Spontaneous Intracerebral Haemorrhage in Young Adults Admitted at a Tertiary Care Hospital in DhakaMohammad Enayet Hussain, Quazi Deen Mohammad, Monsur Habib et al.Spontaneous Intracerebral Haemorrhage (SICH) in young adult occurs due to multiple risk factors. The purpose of the present study was to determine the aetiological factors of spontaneous intracerebral haemorrhage in the young adult patients. This case control study was carried out in the Department of Neurology, Department of Neurosurgery and Department of Internal Medicine at Dhaka Medical College Hospital, Dhaka … …Neuroscience International, Vol. 6, Issue 2 · 2 Oct 2015 · 7,053 accessesView PDFCite
EditorialOpen accessIn the abstractVisceral Pain: Basic Research Concepts and Therapeutic InterventionsVictor V. ChabanThe accumulation of nociceptive diseases that limit normal body functions is a major risk factor for a disability, and visceral pain is one of the most prevalent human health problems. Additionally, many pain-associated diseases are accompanied by the concomitant decline in cognitive and motor performance. The complex interplay and balance between diverse signal transduction mediators, genetic background and environmental factors … …International Journal of Research in Nursing, Vol. 6, Issue 2 · 26 Aug 2015 · 7,152 accessesView PDFCite
Research ArticleOpen accessIn the abstractRespiratory Health of Male Steel Workers in the Eastern Coast of Peninsular MalaysiaNurul Ainun Hamzah, Shamsul Bahri Mohd Tamrin, Noor Hassim IsmailA cross sectional study was carried out to determine the prevalence of respiratory symptoms and associated factors with respiratory health among male steel workers. A total of 424 male workers in the steel production plant were recruited using a stratified random sampling. Subjects were interviewed regarding respiratory symptoms using a British Medical Research Council (BMRC) Questionnaire on respiratory symptoms and … …American Journal of Applied Sciences, Vol. 12, Issue 5 · 27 Jun 2015 · 6,937 accessesView PDFCite