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98 articles for “Peripheral”

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Research ArticleOpen accessIn the abstractImmunomodulatory and Antioxidant Activities of Selenium-Enriched Polysaccharides from Epimedium and Isatis IndigoticaRui Zhang, Jin Li, Jiajia ZhouThis study aims to investigate the effects of selenium modification on polysaccharides derived from two traditional Chinese medicinal herbs-Epimedium (Yinyanghuo) and Isatis root (Banlangen)-in enhancing immune function and antioxidant activity. The purpose is to explore the relationship between structure and function, providing a theoretical basis for the development of efficient plant-based functional antioxidants. Polysaccharides were extracted using an optimized enzymatic … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 3 Feb 2026 · 1,937 accessesView PDFCite
Research ArticleOpen accessIn the abstractGenetic Testing for Inherited Thrombophilia in Women with Recurrent Pregnancy Loss: Prevalence and Risk Assessment of Factor V Leiden, Prothrombin, and MTHFR MutationsLina M. Al Momani, Manal A. AbbasGenetic testing for inherited thrombophilia in women with recurrent pregnancy loss (RPL) may play an important role in detecting high-risk subjects. DNA was extracted from peripheral blood leukocytes. The high pure polymerase chain reaction template preparation kit and Reverse hybridization technique were used to detect the presence of factor V (G1691A, Leiden) (FVL), Factor II (prothrombin, G20210A), and 5,10-methylenetetrahydrofolate reductase … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 29 Nov 2025 · 2,562 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Computational Investigation into the Effect of Equal Channel Angular Processing on the Mechanical Properties of Severely Deformed ZK 60 Alloy Validated by ExperimentsOmar Almenaif, Yaqoub Alhumaydani, Mohammed Alnafisah et al.In this study, the response surface method and finite-element analysis were employed to model the ECAP processing for biodegradable magnesium alloy ZK 60 behavior at 250°C. Using Finite-Element (FE) analysis data was extracted and compared to the what was found by experimenting in order to investigate the effects of the ECAP processing parameters on the plastic deformation behavior of the … …American Journal of Engineering and Applied Sciences, Vol. 13, Issue 2 · 9 Jun 2020 · 7,243 accessesView PDFCite
Research ArticleOpen accessIn the abstractNCCRP-1 Might Not be a Marker of so Called NCC Cells in Common Carp (Cyprinus carpio) LeukocytesMazal Shimon-Hophy, Avi Jacob, Ramy R. AvtalionThe purpose of this study was to verify whether NCCRP-1 is a marker of a unique type of cells in teleost, so-called NCC, or an ubiquitin, like in cytotoxic cells. Therefore, common carp peripheral blood leukocytes were isolated and tested for the binding of fluorescent NCCRP-1 antibody to stained MAIT, γδ T and T cells following stress treatments. The results … …American Journal of Immunology, Vol. 16, Issue 1 · 26 Mar 2020 · 7,757 accessesView PDFCite
Research ArticleOpen accessIn the abstractDoes Iron Modulate Cytokine Production by Desferrioxamine Treated Mononuclear Cells?Hanna Bessler, Meir DjaldettiIron is an essential element for maintaining the normal function of cellular and multicellular organisms and it is closely associated with inflammation and immunity. Macrophages and lymphocytes play an important role in its homeostasis. Hereby we have evaluated cytokine production by iron depleted and iron supplemented human peripheral blood mononuclear cells (PBMC) from healthy adult donors. Non-stimulated or stimulated PBMC … …OnLine Journal of Biological Sciences, Vol. 18, Issue 1 · 7 Jan 2018 · 6,849 accessesView PDFCite
Research ArticleOpen accessIn the abstractFrequencies of the C1236T, G2677T/A, and C3435T Polymorphisms of the MDR1 Gene and their Haplotypes in UzbekistanS. B. Nurmatova, A. A. Abdurakhimov, O. S. Charishnikova et al.P-glycoprotein (P-gp) is encoded by the MDR1 gene and is involved in the pharmacokinetics of drugs. The best-known MDR1 gene polymorphisms are 1236C>T, 3435C>T, and 2677G>T/A, which are associated with protein folding, changes in mRNA levels, and drug pharmacokinetics. The aim of this study was to identify the frequency of distribution of functional polymorphisms C1236T, C3435T, G2677T/A of the MDR1 … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 4 · 5 Dec 2022 · 5,026 accessesView PDFCite
Research ArticleOpen accessIn the abstractExploring the Role of Immune Complexes in Essential HypertensionIvan MilosevicEssential hypertension is a rise of arterial blood pressure whose etiology is unknown. Immune complexes are complexes created by the binding of an antibody to the antigen. They are also called circulating immune complexes because of its precipitation in peripheral blood vessels, commonly on the places of their bifurcation and the places of higher blood pressure (glomerules of kidney or … …American Journal of Immunology, Vol. 18, Issue 1 · 2 Nov 2022 · 9,979 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntioxidant, Analgesic and Anti-inflammatory Effects of Ethanolic Extract of Moroccan Lavandula stoechas L.Hind Ferehan, Mehdi Ait Laaradia, Sara Oufquir et al.Lavandula stoechas L. is a widely used medicinal plant. In Moroccan traditional medicine, it is employed for the treatment of different illness and as an anxiolytic, analgesic or anti-inflammatory remedy. The purpose of this investigation was to assess the antioxidant, antinociceptive and anti-inflammatory effects of the ethanolic extract of Moroccan Lavandula stoechas L. in animal models. Therefore, in vitro anti-oxidant … …OnLine Journal of Biological Sciences, Vol. 21, Issue 4 · 15 Feb 2022 · 5,891 accessesView PDFCite
Research ArticleOpen accessIn the abstractChronic Mental Stress Induces Reversible Reduction of Natural Killer Cells and CD56dim SubpopulationManar M. IsmailGenerally, studying to be a health care provider is a stressful and demanding field and the students have to face many stressors that may affect their general health status including the immune system. This work aimed at studying the effect of prolonged naturalistic life-stress exposure on the percentage of peripheral blood T-lymphocytes and Natural Killer (NK) cells in female laboratory … …American Journal of Immunology, Vol. 13, Issue 3 · 30 Aug 2017 · 7,794 accessesView PDFCite
Research ArticleOpen accessIn the abstractIntravenous Injection of Umbilical Cord-Derived Mesenchymal Stem Cells Improved Regeneration of Rat Liver after 2AAF/CCl4-Induced InjuryIsabella Kurnia Liem, Reni Oktavina, Zakiyah et al.The effectivity of Mesenchymal Stem Cell (MSC) therapy for chronic liver injury is still questioned due to its possibility to have a pro-fibrotic effects. Other consideration is the preferably peripheral Intravenous (IV) route of application rather than direct to the target organ, such as portal vein or splenic vein, since the most of MSC will be trapped in the lung … …OnLine Journal of Biological Sciences, Vol. 21, Issue 2 · 10 Jun 2021 · 6,784 accessesView PDFCite