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72 articles for “Oral Administration”
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Research ArticleOpen accessIn the abstractThe Effect of Ivermectin Pour-on Administration Against Natural Heterakis gallinarum Infestation and its Prevalence in Native PoultryM. H. Khayatnouri, Y. Garedaghi, A. R. Arbati, H. KhaliliProblem statement: One of the real problems that cause the economic prejudice in animal farms yearly is parasitic diseases. To overcome these problems the use of antiparasitic drugs is necessary. Ivermectin is a broad spectrum antiparasitic agent and different routes of its administration such as injection, oral and pour-on were used. The aims of the current study were evaluation of … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 1 · 25 May 2011 · 12,059 accessesView PDFCite
Research ArticleOpen accessIn the abstractCognitive-Enhancing and Antioxidant Activities of Quercetin Liposomes in Animal Model of Alzheimer's DiseaseTerdthai Tong-un, Panakaporn Wannanon, Jintanaporn Wattanathorn, Wathita PhachonpaiProblem statement: Recent findings demonstrated the crucial role of oxidative stress on the pathophysiology of Alzheimer’s Disease (AD). Antioxidant intake is beneficial to delay or inhibit the progression of this disease. Quercetin, a bioflavonoid in fruits and vegetables, has a powerful antioxidant activity both in vitro and in vivo. Claims that quercetin has many biological activities. However, quercetin is rapidly … …OnLine Journal of Biological Sciences, Vol. 10, Issue 2 · 31 Oct 2010 · 7,884 accessesView PDFCite
Research ArticleOpen accessIn the abstractα-Lipoic Acid Therapy Modulates Serum Levels of Some Trace Elements and Antioxidants in Type 2 Diabetic PatientsSalwa Kamal El-Nabarawy, Mona Abd El-Gelel Mohamed, Mohamed Mahmoud Ahmed, Ghada Hany El-ArabiProblem statement: The metabolism of several trace elements has been reported to alter in diabetes mellitus. The disturbance of their serum levels may have a role in the pathogenesis and progress of this disease. In addition, the reports about the status of antioxidants and antioxidant enzymes in diabetic patients are very contradictory. Though α-Lipoic Acid (LA) has long been touted … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 3 · 30 Sep 2010 · 7,764 accessesView PDFCite
Research ArticleOpen accessIn the abstractImpact of L-Carnitine and Cinnamon on Insulin-Like Growth Factor-1 and Inducible Nitric Oxide Synthase Gene Expression in Heart and Brain of Insulin Resistant RatsMona A. MohamedProblem statement: Evaluate the effects of daily administration of L-carnitine and cinnamon extract for two weeks on the expression of Insulin-like Growth Factor-1 (IGF-1) and inducible Nitric Oxide Synthase (iNOS) genes in cardiac and brain tissues of rats with Insulin Resistance (IR). Approach: Rats were divided into 4 groups (8 animals each): Group (1) rats fed control diet (60% starch) … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 3 · 30 Sep 2010 · 8,742 accessesView PDFCite
Research ArticleOpen accessIn the abstractNasal Administration of Quercetin Liposomes Improves Memory Impairment and Neurodegeneration in Animal Model of Alzheimer's DiseaseTerdthai Tong-un, Supaporn Muchimapura, Jintanaporn Wattanathorn, Wathita PhachonpaiProblem statement: At present, the development of protective strategy against Alzheimer’s Disease (AD) is increasing its importance due to the high prevalence of AD, a limitation of therapeutic efficacy and its high impacts on economic and social aspects. The development of the preventive and therapeutic strategy to protect against the path physiology induced by free radicals in AD from antioxidant … …American Journal of Agricultural and Biological Sciences, Vol. 5, Issue 3 · 30 Sep 2010 · 7,746 accessesView PDFCite
Research ArticleOpen accessIn the abstractQuercetin Liposomes via Nasal Administration Reduce Anxiety and Depression-Like Behaviors and Enhance Cognitive Performances in RatsTerdthai Tong-Un, Panakaporn Wannanon, Jintanaporn Wattanathorn, Wathita PhachonpaiProblem statement: At present, the prevalence of neuropsychological disorders particularly anxiety, depression and dementia are increase. Many strategies have been developed in order to increase the efficiency of treatment and decrease side effects. Oxidative stress has been reported to play an important role on various path physiological states. Quercetin is a flavonoid commonly found in fruits and vegetables. It has … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 2 · 30 Jun 2010 · 9,036 accessesView PDFCite
Research ArticleOpen accessIn the abstractCamel's Milk Protects Against Cadmium Chloride-Induced Hypocromic Microcytic Anemia and Oxidative Stress in Red Blood Cells of White Albino RatsMohammad DallakProblem statement: Cadmium is a heavy metal of wide occupational and environmental contamination. In recent years, however, Cadmium has been implicated in the pathogenesis of several clinical disorders. One of the most frequently described problems in aluminum toxicity is anemia. Therefore, the present study was carried out to determine the effectiveness of Camel's milk in alleviating the toxicity of Aluminum … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 4 · 31 Dec 2009 · 8,688 accessesView PDFCite
Research ArticleOpen accessIn the abstractCamel's Milk Alleviates Oxidative Stress and Lipid Peroxidation Induced by Chronic Aluminum Chloride Exposure in Rat's TestesFahaid H. Al-HashemProblem statement: The present study was carried out to examine the effectiveness of Camel’s milk in alleviating aluminum chloride (AlCl3)-induced oxidative stress and lipid peroxidation in rat testes. Approach: White albino male rats (230-250 g) were divided into three groups of 10 rats: A control group, treated with normal saline and two experimental groups, the AlCl3 treated group and the … …American Journal of Applied Sciences, Vol. 6, Issue 11 · 30 Nov 2009 · 7,432 accessesView PDFCite
Research ArticleOpen accessIn the abstractCamel's Milk Protects Against Cadmium Chloride Induced Toxicity in White Albino RatsFahaid Al-Hashem, Mohammad Dallak, Nabil Bashir et al.Problem statement: Cadmium is one of the most dangerous occupational and environmental toxins. It is found in drinking water, atmospheric air and even in food. Cadmium is reported to be very toxic to biological systems. Until now in treating intoxication with this metal, chelating Compounds have been used, burdened with numerous undesirable symptoms. For this reason, many researches are carried … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 3 · 30 Sep 2009 · 9,314 accessesView PDFCite
Research ArticleOpen accessIn the abstractCamel's Milk Protects Against Aluminum Chloride-Induced Normocytic Normocromic Anemia, Lipid Peroxidation and Oxidative Stress in Erythrocytes of White Albino RatsFahaid Al-HashemProblem statement: Aluminum (Al) is an indifferent element from a toxicological point of view. In recent years, however, Al has been implicated in the pathogenesis of several clinical disorders. One of the most frequently described problem in aluminum toxicity is anemia. The present study was carried out to determine the effectiveness of Camel’s milk in alleviating the toxicity of aluminum … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 3 · 30 Sep 2009 · 8,026 accessesView PDFCite