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45 results for “J. B. Fernandez”
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Research ArticleOpen accessIn the author namesDifferential Activities of Glutathione S-Transferase Isoenzymes in Strains of Fasciola Hepatica Susceptible and Resistant to TriclabendazoleV. Fernández, P. Ortiz, M.V. Solana, H. SolanaFasciolosis, a parasitic zoonosis of intrahepatic location, is caused by the trematode Fasciola hepatica. Its control is mainly based on the use of the anthelminthic Triclabendazole (TCBZ). The indiscriminate use of this drug has favored the development of anthelmintic resistance. The Glutation S-Transferases (GSTs) are multifunctional enzymes involved in the detoxification of xenobiotics and endogenous compounds using conjugation with endogenous … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 4 · 10 Dec 2014 · 7,574 accessesView PDFCite
Research ArticleOpen accessIn the author namesRADIOSENSITIZATION OF CANCER STEM CELLS: TARGETING TGFβ, NOTCH OR TELOMERASE TO IMPROVE TUMOR RESPONSE O RADIOTHERAPYIgnacio Fernandez-GarciaRadiation resistant cancer stem cells are the main reason for treatment failure and tumor recurrence after cancer radiotherapy. Increasing biological evidences demonstrate that these cells possess the capacity to repair radiation induced DNA damage, protect themselves from radiation derived reactive oxygen species, survive and proliferate after several fractions of radiotherapy and finally, repopulate the heterogeneity of the tumor. Thus, targeting … …Current Research in Medicine, Vol. 5, Issue 2 · 16 Jul 2014 · 7,459 accessesView PDFCite
Research ArticleOpen accessIn the author namesSHALE GAS EXTRACTION AND WATER CONSUMPTION IN NORTH CAROLINA: A PRIMERManoj K. Jha, Daniel G. FernandezAbout 25,000 acres of area underlying the Deep and Dan River Basins in North Carolina has been identified to contain large shale gas reservoirs that could be used for the natural gas production. This study attempted to quantify the impact of potential hydraulic fracturing (or fracking) activities in the existing water resources of North Carolina. Supply and demand analysis was … …American Journal of Engineering and Applied Sciences, Vol. 7, Issue 1 · 10 Apr 2014 · 8,029 accessesView PDFCite
Research ArticleOpen accessIn the author namesMathematical Genesis of the Spatio-Temporal Covariance FunctionsGema Fernández-Avilés, Jose-María Montero, Jorge MateuProblem statement: Obtaining new and flexible classes of nonseparable spatio-temporal covariances have resulted in a key point of research in the last years within the context of spatiotemporal Geostatistics. Approach: In general, the literature has focused on the problem of full symmetry and the problem of anisotropy has been overcome. Results: By exploring mathematical properties of positive definite functions and … …Journal of Mathematics and Statistics, Vol. 7, Issue 1 · 31 Jan 2011 · 7,938 accessesView PDFCite
Research ArticleOpen accessIn the author names2-Nonenal-Ovulatory Specific Volatiles in Human Saliva throughout Menstrual Cycle by Gas Chromatography and Mass Spectrometry AnalysisS. Alagendran, G. Archunan, K. Rameshkumar et al.Problem statement: The present investigation carry out a pilot study of a novel method to identify the salivary volatiles in different phases of menstrual cycle for the assessment of ovulation detection using gas chromatography and mass spectrophotometer. Approach: The profiles from follicular phase (6-12 days); ovulatory phase (13-14 days) and luteal phase (15-26 days) of menstrual cycle samples were compared … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 3 · 30 Sep 2010 · 8,365 accessesView PDFCite
Research ArticleOpen accessIn the author namesHIV-1 Infection and Central Monoamine NeurotransmittersAdarsh M. Kumar, J. B. Fernandez, Irina Borodowsky et al.Human immunodeficiency virus type 1 (HIV-1) enters the central nervous system (CNS) shortly after infection and gets localized in different brain regions, leading to various types of neuropathological problems. It has been hypothesized that HIV-1 infection mediated neuropathogenesis may also adversely affect the activity of the central monoamine neurotransmitters systems, such as dopamine (DA), and 5-hydroxytryptamine (5-HT, serotonin), resulting in … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 7,491 accessesView PDFCite
Research ArticleOpen accessIn the author namesPrevalence of Human Papillomavirus Types Among Mexican Women with Intraepithelial Lesions and Cervical Cancer: Detection with MY09/MY011 and GP5+/GP6+ Primer SystemsGloria Fernández-Tilapa, Berenice Illades-Aguiar, Dinorah Nashely Martínez-Carrillo et al.Squamous cervical carcinoma (SCC) is the most common cancer found in Mexican women. Human papillomavirus (HPV) infection is a prerequisite for this disease. In Mexico little is known about the prevalence of HPV-types and knowledge of the circulating genotypes by region is limited. The aim of this study was to determine the prevalence and genotypes of HPV in biopsies from … …American Journal of Infectious Diseases, Vol. 3, Issue 2 · 30 Jun 2007 · 7,306 accessesView PDFCite
Research ArticleOpen accessIn the author namesGeneration of Five New Musa Hybrids With Resistance To Black Sigatoka and High YieldRicardo Hernández, Teresa Ramírez, Juan Carlos Noa-Carrazana et al.The ability to identify genetic variation is indispensable to effective management and use of genetic resources. This work is the first approach concerning to generation and genetic differentiation of new Musa hybrid lines obtained in INIVIT (Cuba), crossing Musa acuminata male diploid (AA) x female triploid (ABB), genotypes selected by their resistant character to pests and diseases. From the obtained … …American Journal of Agricultural and Biological Sciences, Vol. 2, Issue 2 · 30 Jun 2007 · 8,811 accessesView PDFCite
Research ArticleOpen accessIn the author namesNeuroendocrine Abnormalities in Drug Abusers and HIV-Infected Individuals: Cortisol Response to Cold Pressor ChallengeMahendra Kumar, Drenna Waldrop-Valverde, Adarsh M. Kumar et al.Although endocrine abnormalities have been reported in HIV-1 infection, the role of risk factors is not understood. Injecting drug use (IDU) is an important risk factor for contracting HIV-infection and studies suggest that substance use may also be associated with endocrine dysfunction. In order to investigate hypothalamic pituitary adrenal (HPA) axis activity in this population, this study investigated cortisol response … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,594 accessesView PDFCite
Research ArticleOpen accessIn the author namesCortisol Response Mediates HIV-1-Related Cognitive Deficits Among Injecting Drug AbusersRaymond L. Ownby, Drenna Waldrop-Valverde, Adarsh M. Kumar et al.The cortisol response is an important measure of the endocrine activity to environmental challenges and has been related to cognitive function and mood. Previous studies have shown that the cortisol response to stress is dysregulated in persons with HIV-1 infection. Since cortisol is neurotoxic and its levels have been related to cognitive dysfunction in various disorders, it is possible that … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 6,759 accessesView PDFCite