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168 results for “HIV”
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Research ArticleOpen accessEvery word in the titleAntisocial Psychopathy and HIV Risk among Alcohol and Other Drug (AOD) Abusing Adolescent OffendersRobert M. Malow, Jessy Dévieux, Rhonda Rosenberg et al.While the consensus is that HIV prevalence has remained low among adolescent offenders, the prevalence of STDs and HIV transmission risk behaviors is alarming, particularly for those abusing alcohol and other drugs and those displaying antisocial or conduct disorder characteristics. In the current study, 269 male and 110 female inner city, culturally diverse alcohol and other drug (AOD) abusing adolescent … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 6,811 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCo-expression of Apoptosis-Related Molecules on Activated CD8+ CD38+ T-cells is Associated with HIV-1 Disease ProgressionJosé W. Rodríguez, Luis A. Rodríguez, Griselle Font et al.CD8+ T cells play a major role in controlling HIV-1 infection through the release of soluble lytic and non-lytic antiviral factors. Their decrease or defective function contributes to the HIV-1 disease progression. HIV-1 disease progression has been associated with a remarkable increase of CD38 expression on CD8+ T-cells. It has been also documented that a significant distribution of HIV-specific CD8+T-cells … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 7,009 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleHIV-1 Infection and Drug-Abuse in India-An Emerging ChallengeMahendra Kumar, Adarsh M. Kumar, Raymond Ownby et al.India has a population of over 1 billion and the first cases of HIV-1 infection were reported from there in 1987. Since then HIV-infection has spread there very aggressively and at present it is reported that there may be 5.7 millions individuals infected with HIV. Unlike the western countries where the infected HIV-1 virus belongs to clade B, in India … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 7,395 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleHIV-1 Infection and Central Monoamine NeurotransmittersAdarsh M. Kumar, J. B. Fernandez, Irina Borodowsky et al.Human immunodeficiency virus type 1 (HIV-1) enters the central nervous system (CNS) shortly after infection and gets localized in different brain regions, leading to various types of neuropathological problems. It has been hypothesized that HIV-1 infection mediated neuropathogenesis may also adversely affect the activity of the central monoamine neurotransmitters systems, such as dopamine (DA), and 5-hydroxytryptamine (5-HT, serotonin), resulting in … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 7,491 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleHIV-1-Specific CTL Recognizing a Scarce Epitope Are Not Suppressed by HIV-1 Protease InhibitorsOtto O. YangHIV-1-protease inhibitors have received growing attention as agents that can affect proteases in human proteasomes, with potentially deleterious effects for HIV-1-specific cellular immunity. Studying the antiviral activity of HIV-1-specific CTL that recognize an epitope that is presented at limiting concentrations on infected cells, we find that several HIV-1 protease inhibitors do not affect their function. These data indicate that these … …American Journal of Immunology, Vol. 3, Issue 1 · 30 Jun 2007 · 7,016 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleConsequence on Treatment of TB Patients Affected by HIV/AIDS A Conceptual ResearchSarder N. Uddin, S. J. Hossain, Md. N. Huda et al.Mycobacterium tuberculosis is an ancient malady, which is one of the world’s most wide spread infectious bacterial agents. Fully one-third of the world’s population is already infected with Mycobacterium tuberculosis, with the greatest burden of disease and infection borne by people in developing countries. Tuberculosis disease is still out of control. Alarming spread of Human Immunodeficiency Virus (HIV) and emergence … …American Journal of Infectious Diseases, Vol. 2, Issue 4 · 31 Dec 2006 · 7,017 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMolecular Mechanisms for Altered Glucose Homeostasis in HIV InfectionPaula W. HruzA complete understanding of the molecular mechanisms leading to HIV-associated insulin resistance remains elusive. Complex interrelationships between genetic predisposition, disease-related body changes and multidrug therapy all contribute to alterations in glucose homeostasis. These abnormalities can be differentiated between acute and reversible changes directly induced by HAART medications and more chronic and less reversible changes due to the development of lipodystrophy … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,877 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAbnormal Glucose Regulation and Treatment Strategies for Insulin Resistance HIV-Infected PatientsSteven GrinspoonHIV-infected patients receiving highly active antiretroviral therapy often demonstrate abnormalities in glucose regulation, in association with changes in fat distribution[1,2]. In the majority of cases, these abnormalities are best characterized by insulin resistance and impaired glucose tolerance, rather than overt diabetes mellitus and fasting hyperglycemia. Insulin resistance may result from direct effects of antiretroviral therapy, changes in fat distribution or … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,387 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleNutritional Alterations in Drug Abusers With and Without HIVJanet E. ForresterMany studies have found that drug abusers have nutritional deficits, including weight deficits. The most plausible explanation for these deficits is dietary insufficiency. However, studies using objective measures of the dietary intake of drug abusers have failed to provide evidence of dietary insufficiency. Other mechanisms have rarely been examined. This article reviews the published literature on the nutritional status of … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,444 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCoronary Heart Disease (CHD) Risk Factors and Metabolic Syndrome in HIV-Positive Drug Users in MiamiMarianna K Baum, Carlin Rafie, Shenghan Lai et al.The frequency of coronary heart disease (CHD) is increasing among HIV seropositive persons. This phenomenon may be related to HIV disease itself, the use of antiretroviral medications and increased length of survival, or the synergism of these factors. In this study we have calculated the 10-year CHD risk estimate and the prevalence of metabolic syndrome in a cohort of 118 … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,989 accessesView PDFCite