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256 articles for “Genes”
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Research ArticleOpen accessEvery word in the titleThrombophilic Genes Mutations in Women with Repeated In-Vitro Fertilization FailureNaglaa Fathy Al Husseini, Ahmad Y. Rezk, Mosad M. Odah et al.Problem statement: Thrombophilia has been recently implicated in early pregnancy loss and IVF implantation failure, by impairing the initial vascularization process occurring at implantation, which is necessary for a successful pregnancy. Approach: The aim of this study is to assess the presence possibility of mutation in thrombophilic genes [Factor V (FV) gene, Prothrombin (PT) gene and Methylenetetrahydrofolate Reductase (MTHFR) gene] … …Current Research in Medicine, Vol. 2, Issue 1 · 29 Mar 2011 · 7,662 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDetection and Localization of Anti and Pro-apoptotic mRNA Genes in Human Colorectal Cancer Using in situ RT-PCRMohd. Nazil Salleh, Boo Siaw Shi, Wan Khairuzzaman Wan Ramli et al.Problem statement: Recent studies using conventional Polymerase Chain Reaction have shown that anti-apoptotic (Cyclooxygenase-2, COX-2 and Nuclear Factor-κB, NF-κB) and proapoptotic mRNA (Bax and Bad) are involved in the tumorigenesis of colorectal cancer. The aim of this study was to localize the expression of anti and pro-apoptotic mRNA genes using Reverse Transcription in situ Polymerase Chain Reaction (RT in situ … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 3 · 30 Sep 2010 · 7,441 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleGenomic Distance between Thymidylate Synthase and Dihydrofolate Reductase Genes Does Not Correlate With Phylogenetic Evolution in BacteriaVitor Hugo MoreauProblem statement: Dihydrofolate Reductase (DHFR) and Thymidylate Synthase (TS) exist as bifunctional enzymes coded into unique polypeptide chain in protozoans. Bifunctional DHFR-TS is associated with an increase in the enzymatic activity by channeling the substrate between the active sites. In some bacteria, DHFR and TS genes are neighbors in the genome, whereas in others, they are located millions of base … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 1 · 31 Mar 2010 · 8,188 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAn Inducible System for the Identification of Target Genes for a Regulator in MycobacteriaShruti Jain, Garima Khare, Pushplata Tripathi, Anil K. TyagiWe described principle and application of an inducible system for identification of target genes of a given mycobacterial protein with a regulatory function. This vector system, a promoterprobe vector, carries (i) promoterless lacZ as the reporter gene and (ii) the mycobacterial gene encoding the regulatory protein under the transcriptional control of the promoter of highly inducible mycobacterial gene encoding acetamidase. … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 3 · 30 Sep 2008 · 7,249 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMeasurement of the Gene Expression and Polymorphisms of c-myc and p53 Genes in HBV Infected PatientsFayed Koutb, Salah Abdel-Rahman, Ehab Hassouna, Amany HaggagThis study explained the c-myc and p53 gene expression and polymorphisms in chronic (40), cirrhosis (30) and Hepatocellular Carcinoma, (HCC) (30) patients related to Hepatitis B Virus (HBV) infection and healthy control (50) in Egypt. Where, c-myc (intron 8) and p53 (codon 72) gene expression and polymorphisms were determined using qRT-PCR and PCR-RFLP techniques. The results showed that c-myc gene … …OnLine Journal of Biological Sciences, Vol. 21, Issue 1 · 22 Feb 2021 · 7,229 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEffect of Heat Stress on the Expression of HSP70, UCP3 and CYP450 Genes in Liver; Longissimus Dorsi and Semitendinosus Muscle of Growing PigsV. Montesinos-Cruz, M. Cota, L. Buenabad et al.High Ambient Temperature (AT) provokes Heat Stress (HS) in animals, which is characterized by increased body temperature, Reactive Oxygen Species (ROS) production and cell damage. Uncoupling Proteins (UCP) may contribute to dissipate body heat, cytochrome P450 (CYP3A4) reduces ROS and Heat Shock Proteins (HSP) prevent protein denaturalization. This study analyzed the expression of HSP70, UCP3 and CYP3A in liver, Longissimus … …American Journal of Animal and Veterinary Sciences, Vol. 14, Issue 4 · 24 Oct 2019 · 7,867 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEvaluation of Nested PCRs targeting the BI and SAG2 Genes For Detection of Toxoplasma gondii Genome in Aqueous Humor From HIV Positive Toxoplasma Retinochoroiditis Patients in a Tertiary Eye HospitalB. Mahalakshmi, K.L. Therese, R. Kirthika et al.Abstract: Problem statement: To evaluate nPCR targeting B1 gene (primer set 1) with 3 other nPCRs targeting B1 gene (primer set 2), 3' end of SAG2 and 5' end of SAG2 gene, for detection of Toxoplasma gondii (T. gondii) genome on AH from HIV positive TRC patients. Approach: DNA extracted from AH of 12 TRC patients and 12 controls (patients … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Dec 2010 · 6,886 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMathematical Genesis of the Spatio-Temporal Covariance FunctionsGema Fernández-Avilés, Jose-María Montero, Jorge MateuProblem statement: Obtaining new and flexible classes of nonseparable spatio-temporal covariances have resulted in a key point of research in the last years within the context of spatiotemporal Geostatistics. Approach: In general, the literature has focused on the problem of full symmetry and the problem of anisotropy has been overcome. Results: By exploring mathematical properties of positive definite functions and … …Journal of Mathematics and Statistics, Vol. 7, Issue 1 · 31 Jan 2011 · 7,938 accessesView PDFCite
Research ArticleOpen accessIn the keywordsGenetic and Environmental Interactions in Spring Wheat Resistance to Bipolaris Sorokiniana Root Rot in KazakhstanYerlan Dutbayev, Ardak Bolatbekova, Aidana Kharipzhanova et al.Common root rot caused by Bipolaris sorokiniana represents a major constraint to wheat production in Kazakhstan. This study evaluated the resistance of 30 spring bread and durum wheat genotypes under diverse environmental and treatment conditions in two contrasting regions (Almaty and Aktobe) during 2024. The experimental design included three treatment regimes: fungicide application, artificial inoculation with the pathogen, and natural … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 7 Mar 2026 · 1,517 accessesView PDFCite
Research ArticleOpen accessIn the keywordsResistance to Antibacterial Agents in Escherichia coli Isolated from Domestic Cats and Dogs in the Northern Region of the Republic of KazakhstanAnara Yeleussizova, Yuliya Aleshina, Anara Mendybayeva et al.The widespread use of antimicrobial agents for pets in veterinary practice has led to the emergence and spread of drug resistance not only in pathogenic but also in opportunistic bacteria. The study aims to evaluate the profile of resistance to antibacterial agents in Escherichia coli strains isolated from domestic cats and dogs, as well as to look into the determinants … …American Journal of Animal and Veterinary Sciences, Vol. 18, Issue 3 · 2 Aug 2023 · 5,525 accessesView PDFCite