327 articles for “Exposure”

Research ArticleOpen accessEvery word in the titleHigh Concentrations of Glucose can Activate or Inhibit Human Erythrocyte Aminolevulinate Dehydratase in vitro Depending Exposure TimeJ. C. Soares, D. Gabriel, V. Folmer et al.Hyperglycemia can cause oxidative stress and inactivate susceptible enzymes. In the present investigation we examined whether short-term incubations (24 or 48 h) with high concentrations of glucose (10-200 mmol L-1) inhibit ALA-D from human erythrocytes. Incubations of erythrocytes for 24 h with glucose (10 up to 40 mmol L-1) resulted in an increase of δ-ALA-D activity (P<0,001). Incubations of erythrocytes … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 4 · 31 Dec 2006 · 6,689 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titlePrenatal Ethanol Exposure Affects the Proliferation and Differentiation of the Osteoblasts from Newborn RatsIsabel Chaves Silva Carvalho, Dennia Perez de Andrade, Noala Vicensoto Moreira Milhan et al.Alcohol exerts teratogenic effects and its consumption during pregnancy may cause various alterations in the fetus, including deficit of bone development. The objective of this study was to evaluate the initial responses, on osteoblasts isolated from newborn rat calvaria, after prenatal ethanol exposure. Nine pregnant rats were divided into three groups according to the diet fed during pregnancy: Rats fed … …OnLine Journal of Biological Sciences, Vol. 15, Issue 3 · 14 Jul 2015 · 6,706 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titlePersonality Traits and Exposure to Stressful Life Events Among Smokers and NonsmokersNataša Šimić, Arta Dodaj, Kristina SesarEarly studies supposed that personality traits and students’ life, which include brings many social and academic changes, may be relevant factors in initiation and maintenance of smoking. The aims of this study were to investigate differences in personality dimensions, as well as exposure to stressful life events among students’ smokers and nonsmokers and finally to examine the predictive contribution of … …Journal of Social Sciences, Vol. 10, Issue 4 · 7 Jan 2015 · 7,556 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleP-Glycoprotein-Mediated Efflux and Drug Sequestration in Lysosomes Confer Advantages of K562 Multidrug Resistance Sublines to Survive Prolonged Exposure to Cytotoxic AgentsNathupakorn Dechsupa, Samlee MankhetkornProblem statement: Cellular drug resistance to anticancer agents is major obstacle in cancer chemotherapy and the mechanisms by which these MDR cells possess for protecting themselves to survive prolonged exposure to cytotoxic agents still debating. The study aimed to clarify the role of P-glycoprotein (Pgp) and enhanced drug sequestration in lysosomes to confer the multidrug resistance K562 cells with varied … …American Journal of Applied Sciences, Vol. 6, Issue 9 · 30 Sep 2009 · 7,508 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titlePassive Transfer of HIV-1 Antibodies and Drug Resistant Virus during a Health Care Worker Accident: Implications for HCW Post-Exposure ManagementCarlos Fernando De Oliveira, Ricardo Sobhie Diaz, Abdallah Harmache et al.Problem statement: We studied in detail a case in which a nurse caring for an HIV-infected child suffered a deep-laceration accident with contaminated blood. Approach: The patient had been treated with zidovudine (ZDV) and the nurse became infected despite prophylactic use of ZDV initiated 2 h after the accident. A reactive anti-HIV-1/2 EIA and an indeterminate western blot (gp120/160 reactivity) … …American Journal of Infectious Diseases, Vol. 4, Issue 4 · 31 Dec 2008 · 6,876 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleEffect of Exposure to Various Durations of Light on Serum Insulin-Like Growth Factor-I in Prepubertal Holstein HeifersL.J. Spicer, B.A. Buchanan, L.T. Chapin, H.A. TuckerOur objective was to determine if prolonged exposure to various durations of light (i.e., photoperiod) would affect serum IGF-I concentrations in heifers. Thus, 16 Holstein heifers, 2 to 4 mo of age, were exposed during a 5-wk pretreatment period to 12 h of cool-white fluorescent light (L) at an intensity of 1200 lux and 12 h of dark (D). At … …American Journal of Animal and Veterinary Sciences, Vol. 2, Issue 2 · 30 Dec 2007 · 6,673 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleExogenous Re-infection by Multiple Exposures to Mycobacterium tuberculosis Contributes to Subsequent Development of Active TuberculosisDiane J. Ordway, Miguel Viveiros, Fernando A. Ventura et al.The majority of tuberculosis (TB) exists in the world’s poorest countries, where costly biosafety level three facilities for containment of infectious TB patients and diagnostic facilities are not affordable. Health care workers (HCWs), in countries with high burdens of tuberculosis (TB) are at risk of nosocomially acquired TB, as there are increased numbers of cases of TB on open hospital … …American Journal of Immunology, Vol. 1, Issue 1 · 31 Mar 2005 · 6,971 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleFSH Receptor and Ki-67 Protein Expressions of Endometrial Macaque in Mid-Luteal Phase after Exposure to Various Doses of Recombinant FSH and Fixed-Dose of GnRH AgonistNurhuda Sahar, Ponco Birowo, Rosalina Thuffi et al.There are many advances in Assisted Reproductive Technologies (ARTs). However, implantation rates are still low. The embryo implantation is a mutual interaction between the blastocyst and endometrium. This study aimed to investigate the endometrial cell proliferation stimulated by recombinant Follicle-Stimulating Hormone (rFSH) in various doses by looking at FSH-Receptor (FSHR) and Ki-67 protein expressions. The studied samples were Stored Biological … …OnLine Journal of Biological Sciences, Vol. 21, Issue 2 · 28 May 2021 · 6,349 accessesView PDF Cite

CorrigendumOpen accessEvery word in the titleCorrigendum: Cocaine Exposure Results in Formation of Dendritic Varicosity in Rat Primary Hippocampal NeuronsHonghong Yao, Crystal Bethel-Brown, Shilpa BuchCorrection to: American Journal of Infectious Diseases http://doi.org/10.3844/ajidsp.2009.26.30, published online 2009; updated 08 February 2021 The authors have recently noticed that the representative image of MAP2 immunostaining in the control group in Figure 3A was incorrectly chosen. This error was inadvertently caused during the assembly of the images due to our negligence in the process of reformatting our manuscript. Original … …American Journal of Infectious Diseases, Vol. 17, Issue 1 · 8 Feb 2021 · 6,419 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleGenotoxicity through Exposure to Particulate Matter (PM10) at two Sites in the Valle de Aburrá, ColombiaVerónica Estrada-Vélez, Lucelly López-López, Lina María Martínez-Sánchez et al.To establish differences in the genotoxic effect of particulate matter (PM10) in exposed individuals at two sites in the Valle de Aburrá (VA). This was a descriptive cross-sectional study of 2 groups of individuals exposed to 67.7 and 45 µg/m3 of PM10 for a minimum of 8 hours/day. The frequency of Chromosomal Abnormalities (CAs) and the mitotic index were evaluated … …OnLine Journal of Biological Sciences, Vol. 19, Issue 1 · 19 Mar 2019 · 8,371 accessesView PDF Cite