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241 results for “Effects of Age”
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EditorialOpen accessIn the abstractProtecting crop species from biotic and abiotic constraints in the era of Global Change: are we ready for this challenge?Marco Landi, Giovanni BenelliReliable and affordable supply of food is of crucial importance to the progress and stability of human societies. During the last century, we have assisted to an extraordinary increase of crop yields, especially for the most widespread and consumed crop species, such as rice, wheat, corn and soybean. The Broadbalk experiment, one of the oldest continuous agronomic experiments in the … …American Journal of Agricultural and Biological Sciences, Vol. 11, Issue 2 · 4 Jun 2016 · 8,399 accessesView PDFCite
EditorialOpen accessIn the abstractImpact of Quantitative Pharmacology on Drug DevelopmentAna Ruiz-Garcia, Kourosh ParivarThesuccess of drug development rests over two well defined pillars, a goodunderstanding of the drug’s clinical pharmacology and the appropriate targetpopulation for whom the clinical use is intended. The label for human prescription drugsrequires a good understanding of the pharmacological effects (pharmacodynamicsor PD) and the mechanism of action of the drug as well as detailed informationof the drug’s Pharmacokinetics (PK): … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 24 Apr 2015 · 7,158 accessesView PDFCite
Research ArticleOpen accessIn the abstractCHRONIC NEONATAL DIAZOXIDE THERAPY IS NOT ASSOCIATED WITH ADVERSE EFFECTSMichele M. Cox, Christopher C. Wendler, Ildiko Erdelyi et al.Diazoxide is an ATP-sensitive potassium channel (KATP) agonist that has been shown to neuroprotective effects. These observations raise the possibility that diazoxide may have potential as a therapeutic agent for other applications. This study investigated (1) the long term effects of chronic neonatal administration of diazoxide and (2) the role of KATP on murin behavior and neurohistology. C57B/6J pups were … …OnLine Journal of Biological Sciences, Vol. 14, Issue 1 · 27 Jan 2014 · 7,447 accessesView PDFCite
Research ArticleOpen accessIn the abstractAdverse Effects of Amphotericin B in Patients of Visceral Leishmaniasis: A Short Survey at Research Hospital PatnaSurabhi Bhatnagar, Shweta, Krishna Murti et al.Leishmaniasis is a disease caused by Leishmania parasite. Leishmania currently affects 12 million people in 98 countries, with an annual incidence of approximately two million new cases. Leishmaniasis is a devastating disease impairing economic productivity and impeding socioeconomic development. The objective of this article was to study the adverse effects of amphotericin B in patients of visceral leishmaniasis which was … …Current Research in Virology, Vol. 2, Issue 1 · 29 Jul 2013 · 6,815 accessesView PDFCite
Research ArticleOpen accessIn the abstractRETRACTED: Evaluation of the Cytotoxic Activity of Aqueous Extract of Schinus terebinthifolius RaddiA. Arnóbio, O. N. Terra Jr., P. R.G. Lemos et al.Phytotherapy consists in all pharmaceutical preparation using certain part of plants as a feedstock with known pharmacological effects for medicinal purposes. In order to a better understanding of the biological effects associated with herbal medicines, many scientific studies have been conducted and developed in recent years. SchinusterebinthifoliusRaddi (Aroeira) is native from Peru and is also found in Europe, Asia and … …American Journal of Infectious Diseases, Vol. 8, Issue 4 · 8 Feb 2013 · 7,611 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effect of Broiler Breeder Ages on the Qualitive and Quantitive Properties of the EggShahabodin Gharahveysi, Seyed Milad Farhadi Niaki, Mehrdad IraniBroiler breeder age is one of the most important factors that affects on egg properties. However by increasing the age of broiler breeder flock, the quality of eggs and consequently the quality of their chick products would be changed. In order to study the effect of broiler breeder flock age on the various aspects of chick products, 300 fertilizable eggs … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 3 · 30 Aug 2012 · 7,826 accessesView PDFCite
Research ArticleOpen accessIn the abstractMulberry Fruits Protects Against Age-Related Cognitive DeclineJintanaporn Wattanathorn, Supaporn Muchimapura, Wipawee Thukhammee et al.Problem statement: The phenolic compounds and anthocyanin contents, the antioxidant and Acetylcholinesterase Inhibitor (AChI) activities of mulberry fruits were determined. Approach: Analysis of phenolic compounds and anthocyanin were performed using Folin Ciocalteu reagent and pH-differential method respectively. The antioxidant activity was determined using DPPH and FRAP assays while AChI activity was determined using Ellman method. Results: The mulberry fruit powder … …American Journal of Applied Sciences, Vol. 9, Issue 9 · 8 Aug 2012 · 7,826 accessesView PDFCite
Research ArticleOpen accessIn the abstractEarly Age Thermal Conditioning Improves Broiler Chick's Response to Acute Heat Stress at Marketing AgeAhmed M. Hassan, P. Gopal ReddyProblem statement: Acute heat stress at marketing age especially in broiler chickens raised in open houses with reduced means of heat exchange leads to economic losses. The objective of this study was to determine beneficial effects of early age thermal conditioning in reducing adverse effects of acute heat stress and decrease losses. Approach: Ninety one day-old broiler chicks were randomly … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 1 · 17 Feb 2012 · 8,660 accessesView PDFCite
Research ArticleOpen accessIn the abstractUncommon Toxicologic Profile at Toxic Doses of CPI-613 (an Agent Selectively Alters Tumor Energy Metabolism) in Rats and Minipigs Reflects Novel MechanismClaudia Maturo, King C. Lee, Robert Rodriguez, Robert ShorrProblem statement: CPI-613 is a novel anticancer agent and the toxicological profile has not been assessed. Accordingly, the objective of these studies was to thoroughly evaluate the Toxicokinetic (TK) effects of CPI-613 in rats and to compare the toxicological profile of rats to minipigs to determine if there were differences between the two animal species. Approach: These studies involved assessments … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 4 · 13 Jun 2011 · 9,582 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Dietary Supplementation with Pumpkin oil (Cucurbita pepo) on Performance and Blood Fat of Broiler Chickens during Finisher PeriodHosna Hajati, Ahmad Hasanabadi, Park W. WaldroupProblem statement: Using most of antibiotic growth promoters as feed additives has been banned by the European Union due to cross-resistance against pathogens and residues in tissues; and scientists search for alternatives to antibiotics, two days. In this view, medicinal plants and essential oils extracted are becoming more important due to their antimicrobial and stimulating effects on animal digestive systems. … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 1 · 26 Apr 2011 · 9,724 accessesView PDFCite