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691 results for “ER Stress”

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Case ReportOpen accessEvery word in the titleBending Stress and Deflection Analysis of Meshing Spur Gear Tooth during the Single Tooth Contact with Finite Element Method and Determination of the Bending StiffnessAntonios D. Tsolakis, Konstantinos G. Raptis, Maria D. MargaritouPurpose of this study is the study of loading and contact problems encountered at rotating machine elements and especially at tooth gears. Tooth gears are some of the most commonly used mechanical components for rotary motion and power transmission. This fact proves the necessity for improved reliability and enhanced service life, which requires precise and clear knowledge of the stress … …American Journal of Engineering and Applied Sciences, Vol. 10, Issue 2 · 3 Jun 2017 · 7,648 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleFluid-Solid Coupling Analysis on Evolution of In-Situ Stress Field by Water Injection in OilfieldJianjun Liu, Yongxiang Zheng, Bohu Zhang et al.Water injection in oilfield may break initial balance of reservoir and lead to re-distribute of stress and deformation of strata. For further research of the evolution characteristics of in-situ field by water injection, the influence on reservoir by water injection was analyzed and different variables were set to study the effects of depth, injection-withdraw ratio and elastic modulus on strain … …American Journal of Engineering and Applied Sciences, Vol. 10, Issue 2 · 6 May 2017 · 8,066 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleHumoral and Cellular Effects of Stress-An Extensive Model SystemMazal Shimon-Hophy, Ramy R. AvtalionThe influence of stress on the immune system of the common carp (Cyprinus carpio) was studied by measuring leukocytes levels using flow cytometry and mRNA immune components by real time qPCR. Acute and chronic oxidative stresses were generated by different regimes of exposure of carp to environmental air. In acute stress, induced by single air exposure, the pro-inflammatory cytokines (IL1β, … …American Journal of Immunology, Vol. 13, Issue 2 · 18 Apr 2017 · 6,728 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEffects of Salt Stress on Ion Balance at Vegetative Stage in Rice (Oryza sativa L.)Kirill V. Azarin, Andrey V. Alabushev, Alexander V. Usatov et al.Rice (Oryza sativa L.) plants were subjected to NaCl stress within 35 days. The shoot dry weight, root dry weight, total survival percentage and contents of inorganic ions in dry samples of stressed plants were measured to identify the physiological adaptive mechanisms by which rice plants at vegetative stage tolerate salt stresses. Laboratory testing of the 10 rice cultivars showed … …OnLine Journal of Biological Sciences, Vol. 16, Issue 1 · 21 Mar 2016 · 7,472 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Evaluation of the Groundwater Influence on the Stress and Strain Behavior around a Tunnel by Analytical MethodsPierpaolo OresteThe presence of an aquifer in the soil causes a change in a relevant way of the stability conditions of a tunnel. The flow of water in the pores, in fact, modifies the stress and strain state of the soil and causes an increase in the thickness of the plastic zone. As a result the loads transmitted on the lining … …American Journal of Applied Sciences, Vol. 12, Issue 10 · 30 Oct 2015 · 6,464 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEffects of Short Term in vitro Stress Hormone Exposure on Regulatory T Cell Number and Function in AsthmaKristina E. Rehm, Gailen D. Marshall, Jr.Asthma is characterized by alterations in the immune system, including regulatory T cells (Treg). Further alterations in Treg numbers and/or function caused by stress hormones may be a contributing factor in asthma pathogenesis. We compared Treg populations and the effects of Dexamethasone (DEX, a laboratory analog of cortisol) on Treg cell number and function in patients with asthma and a … …American Journal of Immunology, Vol. 11, Issue 1 · 24 Apr 2015 · 6,610 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThree Dimensional Investigation of Mode I Stress Intensity Factor Variations in Crack Front Using Finite Element MethodM. M. MirsayarOverall failure may occur in many engineering structures due to the initiation and growth of cracks. Stress intensity factors are extensively used to investigate crack growth in Linear Elastic Fracture Mechanics (LEFM). In many cracked specimens, the stress singularity varies through the thickness and therefore, investigation of stress intensity factor variation in crack front and determination of its maximum value … …American Journal of Engineering and Applied Sciences, Vol. 8, Issue 1 · 26 Jan 2015 · 7,335 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCrosstalk between Oxidative Stress Signaling and HER2 Pathway in Breast CancerVanessa Jacob Victorino, Adriano Martin Felis Aranome, Fernanda Carolina de Campos et al.About 20% of breast cancer patients overexpress the Human Epidermal growth factor Receptor-2 (HER2), also known as ErbB2. HER2-overexpression is associated with enhanced tumor malignancy and its overexpression is related to specific target therapy against breast tumors and other cancers. HER2-mediated pathways in tumor cells act on behalf of the tumor conferring aggressive characteristics. Several reports demonstrated the occurrence of … …American Journal of Immunology, Vol. 10, Issue 4 · 17 Jan 2015 · 8,041 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Participation of Oxidative Stress in Breast Cancer Cells Progression and Treatment ResistancePoliana Camila Marinello, Kaliana Larissa Machado, Rubens Cecchini, Alessandra Lourenço CecchiniThis article presents a general discussion about the participation of oxidative stress in relevant points related to breast cancer progression in vitro. All of the evidences presented here are based on published papers that used breast cancer cells with different phenotype characteristics in their research. We observed that oxidative stress could modulate by several manners the tumor progression and these … …American Journal of Immunology, Vol. 10, Issue 4 · 17 Jan 2015 · 7,512 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEvaluation of the Tunnel Face Stability through a Ground Stress Analysis with a Hemispherical Geometry ApproximationPierpaolo OresteThe evaluation of the stability of the excavation face is an important aspect in the design of a tunnel. When it is not possible to ensure excavation face stability in natural conditions, it is in fact necessary to intervene with remarkably costly reinforcement operations. The analysis of the stability conditions of an excavation face can be conducted, with a certain … …American Journal of Applied Sciences, Vol. 11, Issue 12 · 8 Jan 2015 · 6,730 accessesView PDFCite