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100 results for “Drug Data”
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EditorialOpen accessIn the abstractImpact of Quantitative Pharmacology on Drug DevelopmentAna Ruiz-Garcia, Kourosh ParivarThesuccess of drug development rests over two well defined pillars, a goodunderstanding of the drug’s clinical pharmacology and the appropriate targetpopulation for whom the clinical use is intended. The label for human prescription drugsrequires a good understanding of the pharmacological effects (pharmacodynamicsor PD) and the mechanism of action of the drug as well as detailed informationof the drug’s Pharmacokinetics (PK): … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 24 Apr 2015 · 7,164 accessesView PDFCite
Research ArticleOpen accessIn the abstractTen Bioinformatics Tools for Single Nucleotide Polymorphisms DetectionMahin Ghorbani, Hamed KarimiSingle Nucleotide Polymorphisms (SNPs) as unique genetic variations are widely used as biomarkers for drug designing and development for individualized therapy. SNP genotyping techniques such as SBE with MS detection, SBE with fluorescence intensity detection, The FP-TDI, Pyrosequencing and The TaqMan 5’ nuclease assay are low-speed, time consuming and very expensive. To overcome such disadvantages, bioinformatics tools are emerged as … …Current Research in Bioinformatics, Vol. 3, Issue 2 · 10 Apr 2015 · 17,735 accessesView PDFCite
Research ArticleOpen accessIn the abstractAMINO ACID TRANSPORTERS IN DRUG DISCOVERYMariafrancesca Scalise, Lorena Pochini, Michele Galluccio, Cesare IndiveriAdministered drugs interact with membrane transporters of epithelia, Blood Brain Barrier and other districts influencing their delivery and efficacy. Drugs can also be used as inhibitors of transporters involved in human pathology. Drug-transporter interactions are responsible of off-target effects contributing to toxicity. High Throughput Screening technologies increased the potential applications in therapy or in predicting side effects. These strategies will … …Current Research in Drug Discovery, Vol. 1, Issue 1 · 2 Oct 2014 · 7,101 accessesView PDFCite
Research ArticleOpen accessIn the abstractTHE INFLUENCE OF PERSONALITY ACCENTUATION ON DRUG ADDICTION AMONG STUDENTSElena Aleksandrovna Cheverikina, Andrei Vasilyevich Leifa, Nataliya Alekseyevna Kora et al.To identify character accentuation students who are prone to addiction will allow to adjust their socialization process during the training period in order to increase its effectiveness, as well as it will contribute to the creation of effective psycho-educational programs aimed at reducing the level of their addiction to drugs. Objective: To identify the influence of experimental character accentuation susceptibility … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 2 · 27 Jun 2014 · 7,739 accessesView PDFCite
Research ArticleOpen accessIn the abstractTHE MODEL IN PREVENTING AND SOLVING DRUGS IN THE THAI-LAO BORDER VILLAGESWattana Puttichart, Saner Piromjitpong, Metta MettkarunjitA drug issue is a problem at both national and international levels. The root causes of the problems lie inside and outside the humans. To solve the problems in a sustainable way, it is essential to get cooperation from many parties. The research aimed to study the situations and prevention and solution of drugs in the border villages, to construct … …Journal of Social Sciences, Vol. 10, Issue 1 · 18 Apr 2014 · 7,498 accessesView PDFCite
Research ArticleOpen accessIn the abstractIdentification of Pharmacological Targets Combining Docking and Molecular Dynamics SimulationsIlizaliturri-Flores Ian, Rosas-Trigueros Jorge Luis, Carrillo-Vazquez Jonathan Pablo et al.Studies that include both experimental data and computational simulations (in silico) have increased in number because the techniques are complementary. In silico methodologies are currently an essential component of drug design; moreover, identification and optimization of the best ligand based on the structures of biomolecules are common scientific challenges. Geometric structural properties of biomolecules explain their behavior and interactions and … …American Journal of Agricultural and Biological Sciences, Vol. 8, Issue 1 · 21 Mar 2013 · 8,130 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Self-Medication Among Pharmacy StudentsRiham Waisi, Laila Mouslli, Osama Hussein Mohamed Ibrahim, Suleiman Ibrahim SharifTo determine the incidence of self-medication among Sharjah university students and the impact of medical knowledge on such practice. A pre-validated questionnaire was distributed to 200 pharmacy students during May, 2012. Data were analyzed using SPSS and results expressed as counts and percentages. The overall response rate was 85% with 98% of respondents being Arabs. Females comprised about 91% of … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 4 · 15 Dec 2012 · 10,379 accessesView PDFCite
Research ArticleOpen accessIn the abstractPublic Funding and Affordability of Substance Abuse Treatment ServicesRoberto A. Trevino, Alan J. RichardProblem statement: Substance abuse continues to cause significant personal, social and economic costs to the US economy. In order to decrease these costs, the goal of the US public health policy has been to increase access to drug treatment services by increasing their affordability. Government policy makers try to achieve such a goal by providing direct public funding to private … …American Journal of Economics and Business Administration, Vol. 4, Issue 1 · 28 Feb 2012 · 8,260 accessesView PDFCite
Research ArticleOpen accessIn the abstractObservations on the Relationship between Opioid Medications, Illicit Drugs and Heroin Use in Pain PatientsDavid AlanYee, Michelle Marie Hughes, Rabia Samady Atayee et al.Problem statement: Patients on chronic opioid therapy are monitored to detect illicit drug use in order to deter diversion of their prescription opioids and to ensure medication adherence. The addictive potential of opioid drugs and their similar binding sites in the brain may make them potential gateway drugs for each other. Recent reports indicate that oxycodone has a high probability … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 1 · 7 Jun 2011 · 7,961 accessesView PDFCite
Research ArticleOpen accessIn the abstractPersonality Traits as Predictors towards Readiness to Change among Female Drug AddictsW.S. Wan Shahrazad, Z.M. Lukman, A.R. Roseliza Murni et al.Problem statement: Understanding the personality traits among women who are involved in drug addiction is a crucial issue prior to starting any intervention programs. It may provide an indication of their readiness to receive treatment and change this addictive behavior. This study was conducted to examine the predictive relationship between personality traits and readiness to change among women drug addicts … …American Journal of Applied Sciences, Vol. 8, Issue 2 · 28 Feb 2011 · 7,895 accessesView PDFCite