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57 results for “Cytotoxicity”
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Review ArticleOpen accessIn the abstractDietary Flavonols With Antiviral Efficacy: Safety and Regulatory ConcernsTanisha Parvez, Tanveer Yaqub, Shama Parveen, Mohammad Khalid ParvezGlobally, a variety of pharmacologically-active plant or natural products are commonly consumed as health-protective dietary supplements. These are marketed as crude formulations, isolated metabolites, multi-vitamins, essential amino acids, unsaturated fatty acids and minerals. Of these, pharmacologically-active flavonols like rutin, quercetin, kaempferol, myricetin, isorhamnetin are the most consumed dietary supplements. In addition to their broad-spectrum therapeutic benefits, these are also known … …American Journal of Pharmacology and Toxicology, Vol. 20, Issue 1 · 19 Apr 2026 · 1,866 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnti-Inflammatory Properties of Crude Extracts and Anti-Cancer Properties of Acetone Extract of Moringa Oleifera Lam. Flowers on Cell Line ModelsSandisiwe Maposa, Gloria Aderonke Otunola, Anthony Jide AfolayanIn recent times, Moringa oleifera has earned great interest for its various physiological and therapeutic benefits. Acetone, ethanol, methanol, and aqueous extracts of Moringa oleifera flowers were investigated for anti-inflammatory and anti-cancer potential. Anti-inflammatory capacity was evaluated using the inhibition of nitric oxide production (LPS-induced) on RAW 264.7, and cell viability was appraised with the MTT assay. The potential of … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 1 · 15 Apr 2026 · 1,464 accessesView PDFCite
Research ArticleOpen accessIn the abstractHibiscus Flower Extract and Niacinamide Show Enhanced Whitening Effects in Mouse Melanoma Cells (B16F10)Jae Eun Choi, Tae Su Jang, Jung Min Park et al.Melanoma, a type of cancer that most often occurs on skin exposed to UV rays, is becoming increasingly common. Recent research has focused actively on using natural products. The goal of this study was to compare the melanin-inhibitory effects of Hibiscus (Hibiscus sabdariffa L.) flower Extract (HE) and Niacinamide (NA), a functional ingredient with whitening effects, on melanoma cells. The … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 1 · 9 Feb 2023 · 7,226 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Impact of Di-2-Ethylhexyl Phthalate (DEHP) in Focus on the Reproductive System and Toxicity in Rat or Mammalian ModelVenkataramanaiah Poli, Srinivasulu Reddy MotireddyAbsalan, F., Saremy, S., Mansouri, E., Moghadam, M. T., Moghadam, A. R. E., & Razie, G. (2016). Effects of Mono-(2-Ethylhexyl) Phthalate and Di-(2-Ethylhexyl) Phthalate Administrations on Oocyte Meiotic Maturation, Apoptosis and Gene Quantification in Mouse Model. Cell Journal, 18(4), 503–513. https://doi.org/10.22074/cellj.2016.4717 Acevedo‐Rodriguez, A., Kauffman, A. S., Cherrington, B. D., Borges, C. S., Roepke, T. A., & Laconi, M. (2018). Emerging … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 6 Jun 2024 · 12,990 accessesView PDFCite
Research ArticleOpen accessIn the abstractWound Healing Activity of Chlorogenic Acid in Diabetic Rats is Mediated Through Antibacterial, Antioxidant, and Proliferative EffectsAbdullah Abdulrahman Al-Ghanayem, Mohammed Sanad Alhussaini, AbdulRahman Abdulla Ibrahim Alyahya et al.Chlorogenic acid is known to have antibacterial action against a number of pathogens. This study provides insights into the potentiality of chlorogenic acid in the treatment of chronic infection in wounds. The anti-infective and healing effect of chlorogenic acid in infected wounds was evaluated using diabetic rats. Antibacterial activity of chlorogenic acid against Methicillin-Resistant Staphylococcus Aureus (MRSA) and Multidrug-Resistant (MDR) … …OnLine Journal of Biological Sciences, Vol. 24, Issue 2 · 21 Jan 2024 · 6,154 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Electronic Cigarette E-Liquids on the Adhesion and Growth of Osteoblast CellsAna Carla Lorenz-Vieira, Cesar Augusto Magalhães Benfatti, Mahmoud RouabhiaElectronic cigarettes (E-cigarettes) were designed to replace traditional cigarettes to decrease the harmful effects of smoking. The liquid in e-cigarettes contains different chemicals, such as Propylene Glycol (PG) and Vegetable Glycerin (VG), and may contain nicotine. To be more attractive, e-liquids are supplemented with flavorings. Because vaped e-liquids are shown to be damaging to oral tissues, similar effects could occur … …OnLine Journal of Biological Sciences, Vol. 23, Issue 3 · 29 Apr 2023 · 5,155 accessesView PDFCite
Research ArticleOpen accessIn the abstractCrude Extract of Blue-Green Pigment Derived from the Marine Bacterium Pseudomonas aeruginosa P1.S9 has Antibacterial, Antioxidant, and Cytotoxic ActivitiesAris Tri Wahyudi, Rahmah Nursari, Widya Esti Purwaningtyas et al.Pigment derived from marine bacteria is one of the alternative sources of natural products characterized by beneficial functions for pharmaceutical purposes. This study aimed to evaluate the antimicrobial, antioxidant and cytotoxic activities of the marine bacterium Pseudomonas aeruginosa P1. S9 crude pigment extract and identify its chemical content. Crude pigment extract of this bacterium showed promising antibacterial activities against Pseudomonas … …OnLine Journal of Biological Sciences, Vol. 22, Issue 1 · 4 Mar 2022 · 6,994 accessesView PDFCite
Research ArticleOpen accessIn the abstractSelective Susceptibility of Human Bladder Transitional Cell Carcinoma T24 Cells towards NBD PeptideSankari Durairajan, Charles Emmanuel Jebaraj Walter, Kalaiselvi Periyandavan et al.Bladder cancer is a recurrent disease that often develops chemoresistance and is on the rise in developing countries. After diagnosis surgery followed by immunotherapy and/or chemo- radiation therapy are the available treatments. These treatments do not provide protection against disease progression or recurrence thus highlighting the need to identify and develop drugs that are capable of inhibiting bladder cancer. T24 … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 20 Apr 2020 · 7,787 accessesView PDFCite
Research ArticleOpen accessIn the abstractSelenium Enriched Peanut Protein Alleviates Alcohol-Induced Liver Damage in Mice by Modulating the Composition of the Gut MicrobiotaLin Gao, Jiawei Yuan, Yuhuan Cheng et al.Alcohol Use Disorder (AUD) is one of leading external causes of mortality. Selenium-enriched Peanut Protein (SePP) is a type of Se compound present in Se-enriched plants. Our previous studies showed that SePP possesses potential therapeutic properties and could alleviate alcohol-induced AML-12 cytotoxicity. It spurred us to determine the underlying mechanisms and roles of SePP on gut microbiota. Here, ICR mice … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 4 · 23 Dec 2021 · 6,230 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn Vitro Immunomodulatory and Cytotoxic Potentials of Faloak (Sterculia quadrifida R.Br.) BarkTriana Hertiani, Purwantiningsih, Aji Winanta et al.Faloak (Sterculia quadrifida R.Br., Sterculiaceae) is an Indonesia indigenous plant widely used as a traditional remedy for various health complaints. This study aimed to explore the immunomodulatory and cytotoxicity potentials of Faloak bark by using in vitro techniques. Barks was extracted using water, ethanol and ethanol: water (1:1) separately. Colorimetric analysis was used for the determination of the total phenolic … …OnLine Journal of Biological Sciences, Vol. 19, Issue 4 · 6 Nov 2019 · 8,059 accessesView PDFCite