53 results for “Clinical Trials”

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EditorialOpen accessIn the abstractTREATMENT FOR ANOREXIA NERVOSA: ARE WE MISSING THE MARK?Peta Stapleton, Amy BannatyneAPA, 2013. Diagnostic and Statistical Manual of Mental Disorders, 5th Edn., Arlington, VA: American Psychiatric Publishing. APA, 2014. Anorexia nervosa. www.psychologicaltreatments.org Ben-Tovim, D., K. Walker, P. Gilchrist, R. Freeman and R. Kalucy et al., 2001. Outcome in patients with eating disorders: A 5-year study. Lancet, 357: 1254-1257. DOI: 10.1016/S0140-6736(00)04406-8 Beumont, P.J.V. and S. Touyz, 2003. What kind of illness is … …Current Research in Psychology, Vol. 5, Issue 2 · 20 Sep 2014 · 9,545 accessesView PDF Cite

Research ArticleOpen accessIn the abstractTherapeutic Effects of Highly Purified De-Glycosylated Gcmaf in the Immunotherapy of Patients with Chronic DiseasesLynda Thyer, Emma Ward, Rodney Smith et al.The de-Glycosylated vitamin D binding protein is a powerful Macrophage Activating Factor (GcMAF) that shows multiple biological effects that could be exploited in the immunotherapy of tumours, viral infections and autism. Here we report the observation of a series of clinical cases describing the results obtained administering highly purified GcMAF to patients with diverse types of chronic diseases. These are … …American Journal of Immunology, Vol. 9, Issue 3 · 20 Aug 2013 · 11,868 accessesView PDF Cite

Research ArticleOpen accessIn the abstractConcentration-Effect, Incidence and Mechanism of Nevirapine HepatotoxicityAdikwu Elias, Brambaifa NelsonNevirapine is a dipyridozepinone non nucleoside reverse transcriptase inhibitor approved for use in HIV-infected patients. Its efficacy has been well demonstrated in numerous clinical trials. It has activity against HIV-1 but does not have significant activity against HIV-2 or other retroviruses. Nevirapine is used as one of the components of highly active antiretroviral therapy in HIV patients and in the … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 1 · 19 Apr 2013 · 8,161 accessesView PDF Cite

Research ArticleOpen accessIn the abstractStem Cells in Traumatic Brain InjurySamuel Dobrowolski, Guilherme LepskiTraumatic Brain Injury (TBI) is a devastating clinical condition that often causes permanent incapacity, especially in the younger population. The clinical relevant of TBI justifies the scientific interest in the pathophysiology of TBI, as well as in protective effects and development of treatment options. Stem cells have the ability to induce neuroprotection and neural repair inflammatory suppression, causing tissue reconstruction … …Neuroscience International, Vol. 4, Issue 1 · 12 Apr 2013 · 7,568 accessesView PDF Cite

Research ArticleOpen accessIn the abstractStatin Therapy in the Management of Diabetes Mellitus; How Relevant?Fasanmade Olufemi Adetola, Odeniyi Ifedayo AdeolaDiabetes is associated with the development of premature cardiovascular disease. There have been many clinical trials of statin treatment conducted in patients with Coronary Heart Disease (CHD). Taking a closer look at the subset of those patients with diabetes mellitus puts no doubt on the beneficial effect of lowering cholesterol with statin in these patients. Earlier studies done dwell more … …Current Research in Medicine, Vol. 4, Issue 1 · 25 Mar 2013 · 7,869 accessesView PDF Cite

Research ArticleOpen accessIn the abstractThe Role of Inflammation in Development and Therapy of Malignant MesotheliomaArti Shukla, Jill MillerMalignant Mesothelioma (MM) is an asbestos related malignancy with a poor prognosis and limited therapeutic approaches. The pathogenesis of MM has been linked to asbestos induced inflammation. Asbestos exposure results in reactive oxygen species generation, infiltration of inflammatory cells and prolonged release of multiple cytokines, oxidants and growth factors. The role of inflammation in MM has led to the evaluation … …Current Research in Medicine, Vol. 3, Issue 2 · 30 Aug 2012 · 7,439 accessesView PDF Cite

Research ArticleOpen accessIn the abstractRecent Clinical Advancement of the Effects of Parathyroid Analogues on Fracture Healing in Humans: A Review of LiteratureWen Wei Gerard Ee, Wen Liang Joel Lau, Harish Sivasubramanian, Diarmuid MurphyProblem statement: Numerous animal studies have shown that administration of Parathyroid Hormone (PTH) or a related analogue promotes callus formation and bone union. However, there has yet to be sufficient evidence in human subjects to justify the use of PTH or related analogues in promoting fracture healing. The purpose of this paper is to (1) review all literature involving the … …Current Research in Medicine, Vol. 3, Issue 2 · 27 Aug 2012 · 7,344 accessesView PDF Cite

Research ArticleOpen accessIn the abstractThe 100-Days Oral Toxicity of Tomato Pomace in Healthy MiceWathita Phachonpai, Supaporn Muchimapura, Jintanaporn Wattanathorn et al.Problem statement: Growing attention is being paid to functional food. The beneficial effect of functional food appears to relate to its bioactive ingredient such as substances containing antioxidant. Therefore, the information about the toxicity of the substances is very much essential to recommend the safety for the substances implication in both clinical and application trials. Herein, we have investigated for … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 1 · 23 May 2012 · 7,604 accessesView PDF Cite

Research ArticleOpen accessIn the abstractIn-Depth Review of Stroke Prevention in Patients with Non-Valvular Atrial FibrillationDaych Chongnarungsin, Supawat Ratanapo, Narat Srivali et al.Stroke is a common complication of atrial fibrillation that leads to high morbidity. Anticoagulation therapy significantly reduces the risk of stroke in a selected group of patients. The decision to start anticoagulation needs to be balanced with bleeding risk. During the past years, multiple oral anticoagulation agents were proven to be as effective as warfarin in multiple randomized clinical trials. … …Current Research in Medicine, Vol. 3, Issue 2 · 22 May 2012 · 12,570 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAntimicrobial-Impregnated Discs for Prevention of Intravenous Catheter-Related InfectionsKelly R. Daniels, Christopher R. FreiProblem statement: Healthcare-associated infections are the 5th leading cause of death in the United States. Catheter-Related Bloodstream Infections (CRBSIs) comprise 14% of all healthcare-associated infections and contribute to increased mortality and financial costs. Antimicrobial-impregnated sponge discs to be used surrounding the catheter insertion site are a newer addition to the options available for the prevention of catheter-related infections. Approach: This … …American Journal of Infectious Diseases, Vol. 8, Issue 1 · 24 Feb 2012 · 8,502 accessesView PDF Cite