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77 results for “Clinical Evaluation”
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Research ArticleOpen accessIn the abstractEVALUATING THE SENSITIVITY OF PSEUDOMONAS AERUGINOSA, ESCHERICHIA COLI AND SALMONELLA TYPHI TO VARIOUS BRANDS OF AMPICILLIN AND AMOXICILLIN AVAILABLE IN NIGERIAE. E. Anomohanran, U. B. Owhe-Ureghe, D. A. EhwariemeThe failure of antimicrobial agents in the treatment of some ailments has become a great concern to health care practitioners. This could be as a result of low quality drugs, sneaked into the market by those who fake them, thus, this study was carried out to evaluate the sensitivity of various brands of Amoxicillin and Ampicillin on clinical isolates of … …American Journal of Agricultural and Biological Sciences, Vol. 9, Issue 4 · 22 Oct 2014 · 8,206 accessesView PDFCite
Research ArticleOpen accessIn the abstractPROBABLE CREUTZFELDT JAKOB DISEASE: CASE REPORTYanes Brum Bello, Alexandre Cossenza Pettezzoni De Almeida, Daniela Mendonca Sueth et al.Prion diseases are associated with the accumulation of an abnormal isoformof cellular prion protein (PrPSc), which is the principal constituent of prions. Prions replicate in lymphoreticular tissues before neuroinvasion, suggesting that lymphoreticular biopsy samples may allow early diagnosis by detection of PrPSc. Creutzfeldt-Jakob Disease (CJD) is the most frequent prion disease in humans. Clinical diagnosis of sporadic (CJD) is based … …Current Research in Medicine, Vol. 5, Issue 1 · 14 Mar 2014 · 8,133 accessesView PDFCite
Research ArticleOpen accessIn the abstractNevirapine Hepatotoxicity: Implications of Risk FactorsElias Adikwu, Oputiri Deo, Oru-Bo Precious Geoffrey, D. Akuegbe EnimeyaHighly active antiretroviral therapy is used in the management of HIV/AIDS; it has contributed tremendously in the reduction of mortality and morbidity rate in HIV patients. Despite the outstanding achievement with the use of HAART its major limitation is toxicity. Among these toxicities is hepatotoxicity which is said to be associated with nevirapine containing highly active antiretroviral therapy. Recent reports … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 2 · 3 Jun 2013 · 7,653 accessesView PDFCite
Research ArticleOpen accessIn the abstractConcentration-Effect, Incidence and Mechanism of Nevirapine HepatotoxicityAdikwu Elias, Brambaifa NelsonNevirapine is a dipyridozepinone non nucleoside reverse transcriptase inhibitor approved for use in HIV-infected patients. Its efficacy has been well demonstrated in numerous clinical trials. It has activity against HIV-1 but does not have significant activity against HIV-2 or other retroviruses. Nevirapine is used as one of the components of highly active antiretroviral therapy in HIV patients and in the … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 1 · 19 Apr 2013 · 8,156 accessesView PDFCite
Research ArticleOpen accessIn the abstractCiprofloxacin Induced Chondrotoxicity and TendinopathyElias Adikwu, Nelson BrambaifaCiprofloxacin is one of the fluoroquinolones with a wide clinical acceptability. Rescently there are increasing reports on Ciprofloxacin induce Chondrotoxicity and Tendinopathy in Animal experiment and clinical experience which is of great clinical concern. A comprehensive survey and review of literaure on reported ciprofloxacin induced Chondrotoxicity and Tendinopathy in Humans and Animals was performed. It was observd that ciprofloxacin is … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 3 · 19 Oct 2012 · 10,414 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Role of Inflammation in Development and Therapy of Malignant MesotheliomaArti Shukla, Jill MillerMalignant Mesothelioma (MM) is an asbestos related malignancy with a poor prognosis and limited therapeutic approaches. The pathogenesis of MM has been linked to asbestos induced inflammation. Asbestos exposure results in reactive oxygen species generation, infiltration of inflammatory cells and prolonged release of multiple cytokines, oxidants and growth factors. The role of inflammation in MM has led to the evaluation … …Current Research in Medicine, Vol. 3, Issue 2 · 30 Aug 2012 · 7,437 accessesView PDFCite
Research ArticleOpen accessIn the abstractThree Dimension Reconstruction of Coronary Artery Tree Using Single-View CineangiogramHassan H. Khalil, Rahmita O.K. Rahmat, D. M. Zamrin et al.Problem statement: Whereas most of the conventional techniques propose using multiview cineangiograms to reconstruct 3D objects this article proposes to integrate a Three Dimension (3D) model of the coronary artery tree using a standard single-view cineangiogram. Splitting the cineangiograms into non-sequenced and different angle views is how the data is supplied in this method. Each single view can be used … …Journal of Computer Science, Vol. 6, Issue 12 · 22 Nov 2010 · 8,028 accessesView PDFCite
Research ArticleOpen accessIn the abstractQuality Evaluation Techniques of Processing the ECG SignalMikhled Alfaouri, Khaled DaqrouqIn this research, methods to detect and evaluate the main parameters of the ECG signal are presented in order to improve its clinical properties. Two techniques are addressed in this research, Piecewise method and the Analytical Approach. These techniques are used to determine such as: percent (rms) difference (PRD), signal-noise-ratio (SNR) and the compression ratio (CR) which are used to … …American Journal of Applied Sciences, Vol. 5, Issue 12 · 31 Dec 2008 · 6,655 accessesView PDFCite
Research ArticleOpen accessIn the abstractEmploying New Mathematical Models and Equations to Evaluate Risk-Benefit Criteria of Clinical TherapeuticsDa Yong Lu, Ting Ren Lu, Jian DingCurrent preclinical and clinical evaluation of a drugs or therapy is at first to find out a maximum toxicity tolerance, which is overall fixed. The potential therapeutic dosage will be ranged just lower or within the periphery of these maximum tolerant data. A hidden acceptance among general researchers lies as the toxicity concentration of a drug is always the same … …OnLine Journal of Biological Sciences, Vol. 7, Issue 1 · 30 Jun 2007 · 6,825 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssessment of Quality of Life, Anxiety and Depression in Children with Turner Syndrome: A Case-Control StudyKhaled Saad, Abdulrahman Abdullah Al-Atram, Khaled A. Abdel Baseer et al.Turner syndrome is a genetic disorder that affects only females and is caused by the loss of the whole or a part of the X-chromosome. The aim of this study was to assess the quality of life and frequency of anxiety and depression in a cohort of Egyptian children with Turner Syndrome (TS) diagnosed in Assiut university hospitals, Assiut, Egypt. … …Neuroscience International, Vol. 6, Issue 1 · 13 Mar 2015 · 7,040 accessesView PDFCite