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392 articles for “Delay”
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Research ArticleOpen accessIn the abstractInfluence of Quercetin on Diabetes-Induced Alteration in CYP3A Activity and Bioavailability of Pioglitazone in RatsSudhir Niranjan Umathe, Pankaj Vinod Dixit, Jignesh Manubhai Vaghasiya, Nishant Sudhir JainProblem statement: Quercetin-a common bioflavonoid, is present in herbal preparations consumed by diabetic patients along with routine anti-diabetic agents. We recently showed that quercetin increases the bioavailability of pioglitazone in non-diabetic rats. Thus, present study investigated whether this pharmacokinetic interaction is also evident in diabetic animals, especially because diabetic subjects have altered gastrointestinal (GI) function and CYP3A activity. Approach: The … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 7,819 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Contractor Perception Towers Industrialised Building System Risk in Construction Projects in MalaysiaSalihudin Hassim, Mohd Saleh Jaafar, Saiful Azri Abu Hasan SazalliThe use of IBS (Industrialised Building System) has attracted a lot of countries like Singapore, Sweden, Germany, Japan and the United Kingdom. This system can replace the conventional building system which is labour oriented. However, since the first project of IBS in year 1964 till today, IBS in Malaysia is not well accepted by the construction parties because of failure … …American Journal of Applied Sciences, Vol. 6, Issue 5 · 31 May 2009 · 9,441 accessesView PDFCite
Research ArticleOpen accessIn the abstractPerformance Analysis of a 32-Bit Multiplier with a Carry-Look-Ahead Adder and a 32-bit Multiplier with a Ripple Adder using VHDLHasan Krad, Aws Y. Al-TaieThis study presents a performance analysis of two different multipliers for unsigned data, one uses a carry-look-ahead adder and the second one uses a ripple adder. The study's main focus is on the speed of the multiplication operation on these 32-bit multipliers which are modeled using VHDL, A hardware description language. The multiplier with a carry-look-ahead adder has shown a … …Journal of Computer Science, Vol. 4, Issue 4 · 30 Apr 2008 · 7,391 accessesView PDFCite
Research ArticleOpen accessIn the abstractHormetic and Non-Hormetic Dose-Response Functions in Stress Effects on Memory and Synaptic Plasticity: Issues and MechanismsPhillip R. Zoladz, David M. DiamondOver a century of behavioral research has shown that stress can exert both positive and negative effects on memory. We have explored the idea that the complex effects of stress on learning and memory can be characterized by hormetic- and non-hormetic dose-response functions, in which stress may either stimulate or impair brain memory mechanisms, depending, in part, on the timing … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 8,188 accessesView PDFCite
Research ArticleOpen accessIn the abstractMean Age of Menarche in Trinidad and Its Relationship to Body Mass Index, Ethinicity and Mothers Age of MenarcheEdward O. Uche-Nwachi, A. Odekunle, Johann Gray et al.Menarche is the first menstrual period. It is the final event in the physical manifestation of gonadal development. A study in Europe found that the median age of menarche was 12 years and 11 months and that by the tenth year, 0.8% of the girls had their first menses, while the figure for the eleventh and twelfth years were 3.6 … …OnLine Journal of Biological Sciences, Vol. 7, Issue 2 · 31 Dec 2007 · 8,993 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Phenotypically Suppressed Cancer Cell As a Therapeutic TargetKimberly D. Kyker, Jessica E. Thorpe, Satyendra S. Shenoy et al.Bladder cancer recurs in up to 70% of patients judged to be tumor-free after treatment. Like other cancers, delayed appearance of metastases is common. These findings suggest the malignant phenotype can be suppressed, to emerge later. Following up on previous research in our laboratory showing that normal extracellular matrix can suppress the malignant phenotype of bladder cancers, we here demonstrate … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 4 · 31 Dec 2006 · 6,474 accessesView PDFCite
Research ArticleOpen accessIn the abstractNeuropsychological Dysfunction among HIV Infected Drug AbusersRamani S. Durvasula, Charles H. HinkinHuman immunodeficiency virus (HIV) has been documented to cause direct and indirect central nervous system dysfunction that can be observed as a progressive decline in neuropsychological functioning in a large proportion of persons with HIV and AIDS. Neuropsychological decline in individuals with HIV is characterized by cognitive and motor slowing, attentional deficits, executive dysfunction and memory impairment (characterized by intact … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 7,161 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssociation Between Circulating Early Endothelial Progenitors and CD4+CD25+ Regulatory T Cells: A Possible Cross-talk between Immunity and Angiogenesis?Shmuel Schwartzenberg, Adi Mor, Galia Luboshits et al.Regulatory T-cells (Treg) are a recently defined subset of CD4+ cells that can suppress inflammation and induce tolerance. Phenotypically, T-regs are characterized by a high level of expression of the IL-2 receptor alpha chain, CD25. Endothelial progenitor cells (EPCs) can transform into mature endothelial cells and promote vessel formation by inducing postnatal angiogenesis and vasculogenesis. Herein, we tested the hypothesis … …American Journal of Immunology, Vol. 1, Issue 4 · 31 Dec 2005 · 6,905 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunohistochemical Detection of Apoptosis-Related Proteins in Gerbil Hippocampus Transient Cerebral Ischemia: Neuroprotective Effect of PitavastatinToshiki Himeda, Natsumi Hayakawa, Hiroko Tounai et al.Delayed and selective neuronal damage was caused in the CA1 sector of hippocampus following 5 min of transient cerebral ischemia in gerbils. We investigated the immunohistochemical alterations of apoptosis-related proteins such as bcl-2α, bcl-xs/l, bax, cytochrome c, and active caspase 3 and TUNEL staining in the hippocampus at 1 and 5 hr and 1, 2, 5 and 14 days after … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 4 · 31 Dec 2005 · 6,275 accessesView PDFCite
Research ArticleOpen accessIn the abstractModeling Traffic Flow and Management at Un-signalized, Signalized and Roundabout Road IntersectionsR. Kakooza, L.S. Luboobi, J.Y.T. MugishaTraffic congestion continues to hinder economic and social development and also has a negative impact on the environment. A simple mathematical model is used to analyze the different types of road intersections in terms of their Performance in relation to managing traffic congestion and to establish the condition for stability of the road intersections after sufficiently longer periods of time … …Journal of Mathematics and Statistics, Vol. 1, Issue 3 · 30 Sep 2005 · 6,618 accessesView PDFCite