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318 articles for “Traffic”
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Review ArticleOpen accessIn the abstractThe Triple Immune Argument; Surveillance/Evasion/ Senescence and the Increased Incidence of Acute Myeloid Leukemia Observed with AgeManar M. IsmailAML originates from genetic insults of hematopoietic stem and progenitor cells (HSPCs/HSCs) that was identified earlier as leukemia stem cells (LSCs). In quiescent state, trafficking immune cells are crucial for eradication of aberrant clones and obtaining balance between proliferation and apoptosis to maintain HSCs pool. Regulatory T-cells shield the HSCs from the inflammatory reactions by suppressing T- and B- cells. … …American Journal of Immunology, Vol. 13, Issue 4 · 22 Dec 2017 · 7,806 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Silencing of Septin 1 via Synthetic siRNAs in Schizosaccharomyces pombeSemih Ekimler, Merve Yilmazer, Ercan AricanSeptins are evolutionary conserved GTP-binding proteins and form heterooligomers in cells to interact with cytoskeleton. The main roles of septins in cell are cytokines, membrane interactions, vesicle trafficking and microtubule and actin organization. Non-coding RNAs are key players of gene expression regulation. Small-interfering RNAs (siRNAs) belong to non-coding RNAs, are characterized by sequence complementarity to their target mRNAs. siRNAs silence … …OnLine Journal of Biological Sciences, Vol. 17, Issue 1 · 31 Mar 2017 · 7,237 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Informal Funds Transfer System “Hawala” as a Segment of the Shadow Economy: Social Impact Assessment and Framework for CombatingBakhyt Moldatjaevich Nurgaliyev, Kanat Sametovich Lakbayev, Alexey Vladimirovich Boretsky, Aiman Kudaibergenovna KussainovaThe research considers the problems of social impact assessment in the informal funds transfer systems based on the principles of the ''hawala''. The international experience, leads us to express an opinion that the degree of its public danger through the possibility of financing terrorism, extremism, drug trafficking and transnational organized crime is underestimated. The methods of counteracting these processes by … …American Journal of Applied Sciences, Vol. 12, Issue 12 · 22 Nov 2015 · 6,593 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Diaspora Nigerians’ Image Problem of Drug and Fraud: A Case Study of the Malaysian-Indonesian Experience through Newspaper ReportsMusa Yusuf Owoyemi, Abdul Kadir Haji Din, Ahmad Zaharuddin Sani Ahmad SabriIt is no longer news that the economic and social problems in Nigeria have led to mass migration of Nigerians to other parts of the world for better job opportunities and/or education. South-East Asia has had its fair intake of some of these Nigerians especially in recent times. However, some unscrupulous Nigerians in their bid to make quick money have … …Journal of Social Sciences, Vol. 11, Issue 2 · 24 Jun 2015 · 7,761 accessesView PDFCite
Research ArticleOpen accessIn the abstractDesign a New Bidirectional Transmission Protocol to Improve the Performance of MAC Layer Based on Very High Speed WLANsAli Ahmad Milad, Zul Azri Bin Muhamad Noh, Abdul Samad Shibghatullah et al.This paper presents a new bidirectional transmission protocol with single data frame to computing the performance of MAC layer based on IEEE 802.11n. As high as 600 Mbps of physical data rate is achieved in IEEE 802.11n where high data rate the current MAC layer leads to high performance overhead and low performance of throughput and designing the MAC layer … …Journal of Computer Science, Vol. 11, Issue 5 · 23 Jun 2015 · 6,948 accessesView PDFCite
Research ArticleOpen accessIn the abstractTargeting Cellular Receptors as a Strategy for the Development of New Generation Mucosal VaccinesConstantine Bitsaktsis, Kari Wiedinger, Edmund Joseph GosselinMucosal pathogens are a primary source of infection that require the development of vaccines to induce a specific, protective and long lasting immune response. Despite an urgent need, development of effective mucosal immunization strategies has proven difficult. The literature was reviewed to elucidate cell specific targets that may be utilized to increase the immunogenicity of protective antigens through mucosal vaccination. … …American Journal of Immunology, Vol. 9, Issue 1 · 2 Feb 2013 · 7,026 accessesView PDFCite
Research ArticleOpen accessIn the abstractRal-Binding Protein is Required for the Maturation and Function of Dendritic CellsJozef Borvak, Mukesh Sahu, Varun Joy et al.Problem statement: Dendritic Cells (DCs) integrate responses of innate and adaptive immune system via transmitting pro-inflammatory and regulatory signals to naïve cells within draining lymph nodes. DCs have high capacity for endocytosis, both Clathrin-Dependent (CDE) and Caveolin-Dependent (CvDE). Approach: We have recently shown that ATP-hydrolysis by the multifunctional transporter protein RLIP76 is the primary determinant of the rate of CDE. … …American Journal of Immunology, Vol. 6, Issue 3 · 13 Sep 2010 · 8,095 accessesView PDFCite
Research ArticleOpen accessIn the abstractAAV-Based Targeting Gene TherapyWenfang Shi, Mingxia Yu, Qijun QianSince the first parvovirus serotype AAV2 was isolated from human and used as a vector for gene therapy application, there have been significant progresses in AAV vector development. AAV vectors have been extensively investigated in gene therapy for a broad application. AAV vectors have been considered as the first choice of vector due to efficient infectivity, stable expression and nonpathogenicity. … …American Journal of Immunology, Vol. 4, Issue 4 · 31 Dec 2008 · 6,960 accessesView PDFCite