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336 articles for “In Vitro”
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Research ArticleOpen accessIn the abstractPotent Antielastase and Antityrosinase Activities of Astilbe chinensisSeung-Hun Lee, Sandesh Sancheti, Shruti Sancheti, Sung-Yum SeoProblem statement: In the current scenario, photo-aging is a major problem causing skin wrinkling and hyperpigmentation. Therefore, elastase and tyrosinase inhibitors play an important role in the treatment of skin aging and thus, gaining a special attention in cosmetic industries. Approach: In the screening of Korean medicinal plants to search the potent elastase and tyrosinase inhibitors, the extract of the … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 4 · 31 Dec 2009 · 7,777 accessesView PDFCite
Research ArticleOpen accessIn the abstractStressors Influence on Salmonella enterica Serovar Enteritidis Colonization in BroilersE. S. Soliman, E. Taha, K. D. Infante et al.Problem statement: Poultry industry usually exposing birds to a variety of actions and stressors includs fasting for gastrointestinal emptying before transportation and where birds are often exposed to high environmental temperature during the summer months. These environmental stressors may have influences on bird performance and susceptibility to pathogens such as Salmonella enteritidis by altering the intestinal micrbiota and changes in … …American Journal of Animal and Veterinary Sciences, Vol. 4, Issue 3 · 12 Sep 2009 · 7,187 accessesView PDFCite
Research ArticleOpen accessIn the abstractDrug Interaction between Salinomycin and Exogenous Adrenaline in DogsHamid Rajaian, Javad Sajedianfard, Saeed Nazifi, Ali Moosavi KianProblem statement: Salinomycin is a member of ionophore compounds that may be used in ruminants and pigs as growth promoter or to prevent coccidiosis. There are some reports with respect to the in vitro and in vivo sympathomimetic cardiovascular effects of salinomycin. Available reports indicate that adrenergic impact of the ionophore is brought about by an increase in the secretion … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 2 · 30 Jun 2009 · 7,541 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Flavonoid, Quercetin, Inhibits HIV-1 Infection in Normal Peripheral Blood Mononuclear CellsMadhavan P.N. Nair, Zainulabedin M. Saiyed, Nimisha H. Gandhi, C. N. RamchandProblem statement: Flavonoids and related polyphenols, have been known to possess cardioprotective, anti-tumor, anti-inflammatory, anti-allergic and anti-viral activities. Previous studies have shown that flavonoid, quercetin significantly downregulates expression of pro-inflammatory cytokines in cultured cells via modulation of NFκB and p38MAPK signaling pathways. In the current study, we hypothesize that quercetin exerts anti-HIV activity by differential modulation of pro-and anti-inflammatory cytokine … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 12,184 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Model of Intestinal Anaphylaxis in Whey Sensitized Balb/c MiceNegaoui Hanane, Kaddouri Hanane, Kheroua Omar, Saidi DjamelProblem statement: Cow’s Milk Allergy (CMA) is a common disease in childhood. Pathophysiological mechanisms involved in gastrointestinal symptoms are relatively poorly understood. Approach: Therefore, an experimental model of intestinal anaphylaxis was needed to approach the problem. The aim of this study was to examine the effect of the parenteral sensitization to whey proteins through immune response and local intestine inflammation … …American Journal of Immunology, Vol. 5, Issue 2 · 30 Jun 2009 · 7,126 accessesView PDFCite
Research ArticleOpen accessIn the abstractBiological Control of Rice Blast (Magnaporthe oryzae) by use of Streptomyces sindeneusis isolate 263 in GreenhouseM. Ebrahimi Zarandi, G.H. Shahidi Bonjar, F. Padasht Dehkaei et al.Soil Actinomycetes particularly Streptomyces spp. have antagonistic activity against wide range of plant pathogens. In the recent decades they have attracted high interests as biocontrol agents. In search for finding such principles, in vitro suppression of Magnaporthe oryzae the causal agent of rice blast disease was studied by use of Streptomyces sindeneusis isolate 263 in greenhouse. Spray of rice seedling-leaves … …American Journal of Applied Sciences, Vol. 6, Issue 1 · 31 Jan 2009 · 11,492 accessesView PDFCite
Research ArticleOpen accessIn the abstractTamoxifen Drug Loading Solid Lipid Nanoparticles Prepared by Hot High Pressure Homogenization TechniquesNagi A. ALHaj, Rasedee Abdullah, Siddig Ibrahim, Ahmad BustamamAs drug delivery systems Nanoparticulate widely investigated because of many advantages such as smaller size, controlled drug release potential, targeting ability, enhancement of therapeutic efficacy and reduction of toxicity. So, Solid Lipid Nanoparticles have recently received considerable attention as alternative drug delivery carrier. In this study Solid Lipid Nanoparticles (SLNs) containing tamoxifen, nonsteroidal antiestrogens have been loaded and to be … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 3 · 30 Sep 2008 · 15,168 accessesView PDFCite
Research ArticleOpen accessIn the abstractBetter Understanding of the Immunosuppressive Link between the Lymphocytic Immune Cells and the Decreased Cell Mediated Immunity in Head and Neck Cancer PatientsA.S. Abdulamir, R.R. Hafidh, N. Abdulmuhaimen et al.The purpose of this study was to determine the phenotyping of Peripheral Blood Lymphocytes (PBL) in Head and Neck Cancers (HNCA) patients and to relate this with the level of Cell-Mediated Immunity (CMI) measured by in vitro lymphoproliferative assay, in order to evaluate immune suppression in HNCA patients and its possible mechanisms. Accordingly, one hundred twenty two HNCA patients and … …American Journal of Immunology, Vol. 4, Issue 3 · 30 Sep 2008 · 7,303 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvidence of Oxidative Stress in Autism Derived from Animal ModelsXue Ming, Michelle A. Cheh, Carrie L. Yochum et al.Autism is a pervasive neurodevelopmental disorder that leads to deficits in social interaction, communication and restricted, repetitive motor movements. Autism is a highly heritable disorder, however, there is mounting evidence to suggest that toxicant-induced oxidative stress may play a role. The focus of this article will be to review our animal model of autism and discuss our evidence that oxidative … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 7,115 accessesView PDFCite
Research ArticleOpen accessIn the abstractTherapeutic Effects of Phyllanthus Species: Induction of TNF-α-mediated Apoptosis in HepG2 Hepatocellular Carcinoma CellsSripathi M. Sureban, Dharmalingam Subramaniam, Paramasivam Rajendran et al.Phyllanthus species, especially P. amarus is a medicinal plant with hepatoprotective activity, believed to occur in part by inhibiting hepatitis B virus function. The pathogenesis mechanism of viral hepatitis is closely related to hepatocyte necrosis apoptosis. The aim of our study was to investigate the in vitro effects of extracts from three Phyllanthus species, P. urinaria, P. amarus and P. … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 4 · 31 Dec 2007 · 9,005 accessesView PDFCite