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Research ArticleOpen accessIn the abstractConsequence on Treatment of TB Patients Affected by HIV/AIDS A Conceptual ResearchSarder N. Uddin, S. J. Hossain, Md. N. Huda et al.Mycobacterium tuberculosis is an ancient malady, which is one of the world’s most wide spread infectious bacterial agents. Fully one-third of the world’s population is already infected with Mycobacterium tuberculosis, with the greatest burden of disease and infection borne by people in developing countries. Tuberculosis disease is still out of control. Alarming spread of Human Immunodeficiency Virus (HIV) and emergence … …American Journal of Infectious Diseases, Vol. 2, Issue 4 · 31 Dec 2006 · 7,017 accessesView PDFCite
Research ArticleOpen accessIn the abstractApplications of Real-time Reverse Transcription Polymerase Chain Reaction in Clinical Virology Laboratories for the Diagnosis of Human DiseasesR. Manojkumar, V. MrudulaEarly diagnosis that prevents further expansion of the causative agent and thereby aids control and eradication of infectious agents is critical for countries trying to obtain a particular disease free status. In these diagnostics speed is paramount, including the assay’s applicability, sensitivity, specificity, cost effectiveness and patentability. Real-time Reverse Transcription PCR (rRT-PCR) has revolutionized the field of molecular biology and … …American Journal of Infectious Diseases, Vol. 2, Issue 4 · 31 Dec 2006 · 6,553 accessesView PDFCite
Research ArticleOpen accessIn the abstractInternalizing Versus Non-internalizing Receptors for Targeting L-Methioninase to Cancer CellsXiao-Ping Zang, Naveen R. Palwai, J. T. Pento, Roger G. HarrisonWe reported previously that L-methioninase targeted to the urokinase receptor of MCF-7 breast cancer cells is significantly more effective in inhibiting cell proliferation and migration than free L-methioninase both in vitro and in vivo. L-methioninase was targeted by linking at its amino terminus to an amino-terminal fragment (ATF) of urokinase. The ATF was selected for targeting because is has previously … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 3 · 30 Sep 2006 · 7,817 accessesView PDFCite
Research ArticleOpen accessIn the abstractRole of AP-1 Antagonism in Growth Inhibition of Cervical Cancer Cell Lines by RetinoidsShennan Lu, Doris M. BenbrookRetinoid compounds induce multiple molecular effects that need to be taken into consideration in the development of theses agents as pharmaceuticals for cancer chemoprevention. Inhibition of cancer cell growth by retinoids is thought to occur through at least two mechanisms of transcriptional regulation resulting from direct binding of retinoids to nuclear retinoid receptors (RARs and RXR’s). First, the nuclear receptors … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 3 · 30 Sep 2006 · 7,477 accessesView PDFCite
Research ArticleOpen accessIn the abstractMolecular Mechanisms for Altered Glucose Homeostasis in HIV InfectionPaula W. HruzA complete understanding of the molecular mechanisms leading to HIV-associated insulin resistance remains elusive. Complex interrelationships between genetic predisposition, disease-related body changes and multidrug therapy all contribute to alterations in glucose homeostasis. These abnormalities can be differentiated between acute and reversible changes directly induced by HAART medications and more chronic and less reversible changes due to the development of lipodystrophy … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,877 accessesView PDFCite
Research ArticleOpen accessIn the abstractAbnormal Glucose Regulation and Treatment Strategies for Insulin Resistance HIV-Infected PatientsSteven GrinspoonHIV-infected patients receiving highly active antiretroviral therapy often demonstrate abnormalities in glucose regulation, in association with changes in fat distribution[1,2]. In the majority of cases, these abnormalities are best characterized by insulin resistance and impaired glucose tolerance, rather than overt diabetes mellitus and fasting hyperglycemia. Insulin resistance may result from direct effects of antiretroviral therapy, changes in fat distribution or … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,387 accessesView PDFCite
Research ArticleOpen accessIn the abstractIsolation and Mutagenesis of Streptokinase Producing BacteriaThaer Taleb Abed Abdelghani, Adinarayana Kunamneni, Poluri EllaiahOf 103 β-haemolytic Streptococci (with haemolytic activity) in total were isolated from different samples of blood and biomass from infected throat, 47 isolates exhibited streptokinase (SK) activity. T3, identified as a new variant of Streptococcus equisimilis, was found to be excellent SK producer in submerged fermentation and was selected for strain improvement studies. This strain was mutagenized by UV and … …American Journal of Immunology, Vol. 1, Issue 4 · 31 Dec 2005 · 7,789 accessesView PDFCite
Research ArticleOpen accessIn the abstractRational Rules of Thumb in Finite Dynamic Games N-person Backward Induction with Inconsistently Aligned Beliefs and Full RationalityYanis VaroufakisRecent work has cast considerable doubt on the plausibility of specific assumptions about how rational agents form out-of-equilibrium beliefs in finite extensive games in which beliefs are induced backwards. The point is that the resulting consistently aligned beliefs are incoherent in view of the counterfactuals they rely on. This study asks: How will the possibility of inconsistently aligned beliefs affect … …American Journal of Applied Sciences, Vol. 2, Issue 13 · 16 Dec 2005 · 8,114 accessesView PDFCite
Research ArticleOpen accessIn the abstractChromium (III) Removal and Recovery from Tannery Wastewater by Precipitation ProcessAbass Esmaeili, Alireza Mesdaghi nia, Reza VazirinejadChromium (III) salts are the most widely used chemicals for tanning processes, but 60-70% of total chromium salts reacts with the hides. In the other word, about 30-40% of the chromium amount remains in the solids and liquid wastes (especially spent tanning solutions). Therefore, the removal and recovery of the chromium content of these wastewaters are necessary for environmental protection … …American Journal of Applied Sciences, Vol. 2, Issue 10 · 31 Oct 2005 · 8,679 accessesView PDFCite
Research ArticleOpen accessIn the abstractNeisser’s Cycle of Perception: Formal Representation and Practical ImplementationIgor A. Chimir, Waheeb A. Abu-Dawwas, Mark A. HorneyThis article presents results of a theoretical investigation of the application of the object-oriented Unified Modelling Language to a formal description of Neisser’s cycle of perception. The article includes class diagrams, modelling the spatial structure of Neisser’s cycle of perception and demonstrates how these formal descriptions can be applied to the area of modelling the problem-independent dialogue process. The basis … …Journal of Computer Science, Vol. 1, Issue 2 · 19 Oct 2005 · 5,104 accessesView PDFCite