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336 articles for “In-vitro”
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Research ArticleOpen accessIn the abstractDetection of Extended-Spectrum β Lactamases and AmpC β-Lactamase Production in Escherichia coli Causing Urinary Tract Infection among HIV and Non-HIV PatientsPadmavathy Kesavaram, Padma Krishnan, Rajasekaran SikhamaniProblem statement: Opportunistic infections have been documented as a leading cause of morbidity among HIV patients. Gram negative pathogens that elaborate beta-lactamases have been reported to be associated with increased morbidity and mortality, especially amongst immunocompromised patients on intensive care and high-dependency units. The most common mechanism of β-lactam drug resistance in Escherichia coli include ESBL, AmpC production. Approach: In … …Current Research in Medicine, Vol. 2, Issue 1 · 18 Aug 2011 · 7,837 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntiplaque Activity of Juglans Regia L. and Characterization of Juglone from Juglans Regia L.Pandita Nancy, Mantri Manasi, Alice VargheseProblem statement: Oral hygiene has become the most important in current era. Due to growing need for aesthetic and hygeine oral hygiene has gained impetus. In this research paper we have studied new varieties of natural products which help in improving the oral hygiene. Approach: Two varieties of Juglans regia bark were extracted using hot and cold extraction methods and … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 1 · 27 May 2011 · 9,657 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effect of Rumen Acid Load on Postpartum Performance and Blood Metabolic Responses in Transition Holstein CowsSadjad Danesh Mesgaran, Alireza Vakili, Alireza Heravi Moosavi, Ghasem KoolabadiProblem statement: The transition period is the most stressful time in the production cycle of a dairy cow because of depressed feed intake, endocrine and metabolic changes at parturition. The aim was to determine the effect of rumen acid load on postpartum performance and metabolic parameters in transition Holstein cows. Approach: The Acidogenicity Values (AV) of the diets were determined … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 1 · 25 May 2011 · 7,444 accessesView PDFCite
Research ArticleOpen accessIn the abstractSynthesis and Calcium Channel Blocking Activity of 1, 4-Dihydropyridine Derivatives Containing Ester Substitute and Phenyl Carbamoyl GroupBassem Sadek, Khairi Mustafa Salem Fahelelbom, Laurentiu Morusciag, Sigurd ElzProblem statement: Several studies on the synthesis of new nifedipine analogs have been carried out, but the literature reveled that no study on the synthesis and calcium channel blocking activity of the substituted ester with an amide (5-phenylcarbamoyl) moiety has been reported. Approach: Six new derivatives of m-nifedipine have been successfully synthesized by substituting an ester moiety with an amide … …American Journal of Applied Sciences, Vol. 8, Issue 4 · 18 Apr 2011 · 8,253 accessesView PDFCite
Research ArticleOpen accessIn the abstractIdentification the Specific Relationships among Physical Parameters which Use to Quantify Inactivation Effect of Charged Particles at Low DosesAbubaker Ali Yousif, Ismail Bin Bahari, Muhamad Samudi YasirProblem statement: The relationships among physical qualities parameters which are characterized charged particles are not extensively determined for all types of ionizing radiations; the specific physical parameters that are also qualified to quantify the radiation effects of charged particles have been investigated. Approach: Secondary data of charged particles which are used to irradiate mammalian cells in vitro has been employed … …Physics International, Vol. 1, Issue 2 · 31 Dec 2010 · 6,533 accessesView PDFCite
Research ArticleOpen accessIn the abstractCognitive-Enhancing and Antioxidant Activities of Quercetin Liposomes in Animal Model of Alzheimer's DiseaseTerdthai Tong-un, Panakaporn Wannanon, Jintanaporn Wattanathorn, Wathita PhachonpaiProblem statement: Recent findings demonstrated the crucial role of oxidative stress on the pathophysiology of Alzheimer’s Disease (AD). Antioxidant intake is beneficial to delay or inhibit the progression of this disease. Quercetin, a bioflavonoid in fruits and vegetables, has a powerful antioxidant activity both in vitro and in vivo. Claims that quercetin has many biological activities. However, quercetin is rapidly … …OnLine Journal of Biological Sciences, Vol. 10, Issue 2 · 31 Oct 2010 · 7,884 accessesView PDFCite
Research ArticleOpen accessIn the abstractQuality evaluation of Ketoprofen Solid Dosage Forms Available in the Pharma-Market of BangladeshKamrun Naher, Gazi Md. Monjur Murshid, Md. Golam Hossain et al.Problem statement: Ketoprofen, a widely used analgesic and anti-inflammatory drug, was available in two types of solid dosage forms in the pharma-market of Bangladesh: enteric-coated tablet and capsule of sustained-release pattern. Seven brands of ketoprofen enteric-coated tablets and four brands of ketoprofen sustained release capsules were studied for their in-vitro release behavior as well as potency status. Approach: The studies … …American Journal of Applied Sciences, Vol. 7, Issue 10 · 31 Oct 2010 · 8,051 accessesView PDFCite
Research ArticleOpen accessIn the abstractFormulation and Evaluation of a Novel Needle-Free Hepatitis B Surface Antigen Delivery SystemC. D. Licy, K. Premalatha, Annie Shirwaikar, Arun ShirwaikarProblem statement: Hepatitis B is a major public health problem, killing 1-2 million people annually, despite the introduction of an effective vaccine in 1982. Approximately 400 million persons worldwide have chronic hepatitis B. This is due to problems associated with vaccine delivery, stability and cost. Hence the present challenge in Vaccinology is to develop safer, cheaper and easy-to-deliver forms of … …Current Research in Medicine, Vol. 1, Issue 2 · 30 Oct 2010 · 6,821 accessesView PDFCite
Research ArticleOpen accessIn the abstractPreliminary Study on Immunomodulatory Effect of Sarang-Semut Tubers Myrmecodia tuberosa and Myrmecodia pendensTriana Hertiani, Ediati Sasmito, Sumardi, Maria UlfahProblem Statement: Sarang-Semut tubers, Myrmecodia tuberosa and M. pendens (Rubiaceae) are both medicinal plants originating from Papua which have broad range of therapeutic values including those to improve vitality. Nevertheless, no scientific proof is available so far on their immunomodulatory effect. The purpose of this study was to reveal the potency of Sarang-Semut tubers as immunomodulatory agent by evaluating their … …OnLine Journal of Biological Sciences, Vol. 10, Issue 3 · 30 Sep 2010 · 13,403 accessesView PDFCite
Research ArticleOpen accessIn the abstractInhibition of U6 snRNA Transcription by PTENStephanie Cabarcas, Kounosuke Watabe, Laura SchrammProblem statement: RNA polymerase III (RNA pol III) is responsible for transcribing many of the small structural RNA molecules involved in RNA processing and protein translation, thereby regulating the growth rate of a cell. RNA pol III transcribes both gene internal (tRNA) and gene external (U6 snRNA) promoters and proper initiation by RNA polymerase III requires the transcription initiation factor … …OnLine Journal of Biological Sciences, Vol. 10, Issue 3 · 30 Sep 2010 · 8,557 accessesView PDFCite