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74 results for “sera”
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Research ArticleOpen accessIn the abstractAnti-β2 Glycoprotein-I Antibody in Acute Myocardial InfarctionMohammad Shojaei, Abdolreza Sotoodeh Jahromi, Hamideh Ebadat et al.Problem statement: Ischemic cardiac manifestations have been reported in a various percentage of patients with anti-phospholipid antibodies. Data concerning the relation between anti- Phospholipid (aPL) antibodies and myocardial infarction in subjects without evidence of overt autoimmune disease are conflicting. Anti-beta2 glycoprotein-I (anti-beta2-GPI) antibody is detected in various diseases like rheumatoid arthritis, systemic lupus erythematosus and anti-phospholipid antibody syndrome. The study … …American Journal of Applied Sciences, Vol. 8, Issue 8 · 18 Jul 2011 · 7,051 accessesView PDFCite
Research ArticleOpen accessIn the abstractSerological Evaluation of Brucella abortus S99 Lipopolysaccharide Extracted by an Optimized MethodAli Sharifat Salmani, Seyed Davar Siadat, Mohammad Reza Fallahian et al.Problem statement: Brucellosis is a globally found infectious disease and there is no licensed vaccine against human brucellosis. The present study carried-out to evaluate the potency of our modified extracted lipopolysaccharide (LPS) of B. abortus to elicit specific anti-Brucella antibodies in animal model (Rabbit) as a part of a candidate vaccine for brucellosis. Lipopolysaccharide is one of the main virulence … …American Journal of Infectious Diseases, Vol. 5, Issue 1 · 31 Mar 2009 · 9,080 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Storage Time and Temperature on Serum AnalytesAbdoljalal MarjaniInformation on the measured concentration of serum analytes during storage of serum samples is often incomplete and sometimes contradictory. The 10 analytes have not studied in this area in healthy subjects. The aim of present study was designed to determine the effect of storage time and temperature on the laboratory results of 10 analytes in sera from apparently healthy adult … …American Journal of Applied Sciences, Vol. 5, Issue 8 · 31 Aug 2008 · 8,870 accessesView PDFCite
Research ArticleOpen accessIn the abstractC-Terminal Region of Dengue Virus Nonstructural Protein 1 Is Involved in Endothelial Cell Cross-Reactivity via Molecular MimicryShu-Wen Wan, Chiou-Feng Lin, Mei-Chun Chen et al.Infection with dengue virus (DV) causes diseases ranging from self-limited dengue fever to life-threatening dengue hemorrhagic fever and dengue shock syndrome. Vascular leakage, thrombocytopenia and bleeding are the clinical manifestations associated with dengue hemorrhage. We previously showed that anti-DV nonstructural protein 1 (NS1) antibodies (Abs) cross-reacted with endothelial cells. The potential target proteins on endothelial cell surface recognized by anti-DV … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,560 accessesView PDFCite
Research ArticleOpen accessIn the abstractPatient and Mouse Antibodies against Dengue Virus Nonstructural Protein 1 Cross-React with Platelets and Cause Their Dysfunction or DepletionChiou-Feng Lin, Huan-Yao Lei, Ching-Chuan Liu et al.Thrombocytopenia is a clinical manifestation in dengue virus (DV) infection, yet its pathogenic mechanisms are unresolved. We previously showed that dengue patient sera contained antibodies cross-reactive with platelets. In this study, we demonstrated that the anti-platelet activity of dengue patient sera was due to the antibodies against DV nonstructural protein 1 (NS1). Studies using DV-infected or recombinant NS1-immunized mouse sera … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,321 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnti-Prm Antibody as an Autoantibody in Dengue Virus InfectionKao-Jean Huang, Yu-Tien Cheng, Yee-Shin Lin et al.We have reported that anti-prM antibody is an enhancing antibody that enhances DV infection of non-Fc receptor bearing cells by dual specificity. We identified the epitope recognized by this anti-prM antibody, M3, which is located at the a.a.53-67of the prM protein nearby the prM/M cleavage junction and these anti-M3 antibodies could be detected in dengue patients sera. Surprisingly, this anti-prM … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,304 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnti-Platelet and Anti-Endothelial Cell Autoantibodies in Vietnamese Infants and Children with Dengue Hemorrhagic FeverNguyen Thanh Hung, Nguyen Trong Lan, Yee-Shin Lin et al.Dengue hemorrhagic fever (DHF) is a serious public health problem. Increased vascular permeability and thrombocytopenia are the hallmarks of DHF. The mechanisms involved in DHF/Dengue shock syndrome (DSS) pathogenesis is not fully understood. This study gives evidence of the presence of antibodies which cross-reacted with platelets, and endothelial cells in the sera of Vietnamese infants and children with DHF/DSS. The … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,369 accessesView PDFCite
Research ArticleOpen accessIn the abstractSeroprevalence of Human Immunodeficiency Virus and Syphilis Infections among Patients Attending the STD, Gyn. and Obs., ANC Clinics of Northern India: Observations from Seven Rounds of Sentinel Surveillance (1998-2004)Tahziba Hussain, K. K. Kulshreshtha, V. S. Yadav et al.The data of HIV sentinel surveillance, i.e., National Annual Sentinel Surveillance (NASS) carried out under the aegis of National AIDS Control Organisation (NACO) of seven rounds revealed that the prevalence of HIV infection is less among the attendees of STD, Obs. & Gyn., Antenatal ( ANC) clinics whereas that of Syphilis is high. This study was carried in order to … …American Journal of Infectious Diseases, Vol. 2, Issue 1 · 31 Mar 2006 · 7,061 accessesView PDFCite
Research ArticleOpen accessIn the abstractIsolation and Public Health Significance of Non-Polio Enteroviruses in Healthy Nigerian ChildrenMuhammad Sagir Shehu, Yunusa Thairu, Idris Abdullahi Nasir, Fatima YahayaNon-Polio Enteroviruses (NPEVs) are in circulation all over the world. Some of these viruses have been associated with several chronic diseases such as cardiopathy, myositis, acute flaccid and spastic paralysis in children which mimic poliomyelitis. This study sought to ascertain whether Non-Polio Enteroviruses (NPEVs) are silently shed by apparently healthy school children in Bauchi state, Nigeria. This cross-sectional study involved … …American Journal of Infectious Diseases, Vol. 12, Issue 1 · 24 Mar 2016 · 7,691 accessesView PDFCite
Research ArticleOpen accessIn the abstractPREVALENCE OF AUTOANTIBODIES REVEALS A PREDOMINANT SMA AND ANCA-PR3/MPO PATTERN IN HIV INFECTION AND SMA IN HAV-INFECTED CHILDRENLuz M. Navarta, Carlos A. Espul, Nelson Acosta-RiveroHepatitis A Virus (HAV) and Human Immunodeficiency Virus (HIV) have been associated with development of autoantibodies and autoimmune manifestations in children. Autoimmune Hepatitis (AIH) is particularly aggressive in children/adolescents with a more severe outcome. Thus, studying the mechanisms of virus-related autoimmune disorders in children is a relevant topic of research. We aimed to study the prevalence of autoantibodies in plasma … …American Journal of Immunology, Vol. 10, Issue 3 · 18 Sep 2014 · 7,038 accessesView PDFCite