48 results for “reactive oxygen species”

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Research ArticleOpen accessIn the abstractAluminium-Induced Hepatotoxicity and the Protective Role of Withania somnifera (Ashwagandha) in Wistar RatsAnchana Babu, Rekha D Kini, Nayanatara Arun Kumar, Megha GokulAluminium is a widely distributed environmental contaminant whose chronic exposure leads to accumulation in multiple organs, including the liver, resulting in oxidative stress and tissue damage. When reactive oxygen species production exceeds the body's antioxidant defense capacity, cellular injury ensues — a mechanism central to aluminium-induced hepatotoxicity. Withania somnifera (Ashwagandha), an evergreen herb of the Solanaceae family widely cultivated in … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 6 Apr 2026 · 1,451 accessesView PDF Cite

Literature ReviewOpen accessIn the abstractUnraveling NETosis: From Immune Mechanisms to Therapeutic InnovationsAnastasia V. Poznyak, Alexey V. Churov, Gulalek Amanmyradovna Babayeva et al.Neutrophil Extracellular Traps (NETs) are integral to immune responses, serving both protective and pathological roles in inflammatory diseases. Despite increasing recognition of NETs, significant gaps remain in understanding the nuanced mechanisms of NETosis and its implications for health and disease. This review systematically explores NETosis—the formation of NETs—by elucidating the molecular signaling pathways and cellular mechanisms involved. We highlight the … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 21 Feb 2026 · 1,685 accessesView PDF Cite

Research ArticleOpen accessIn the abstractEpigenetic Regulation of Extracellular Matrix Remodeling in Skin Aging: Mechanisms and InteractionsJiguang Yang, Yusong Shi, Xiaoqing YanSkin aging results from complex interactions between genetic factors, environmental stressors, and epigenetic modifications that regulate extracellular matrix (ECM) remodeling. Accumulation of senescent cells impairs tissue regeneration through mechanisms including telomere shortening, reactive oxygen species accumulation, and ultraviolet (UV) radiation exposure. While epigenetic pathways regulate skin homeostasis, regeneration, and senescence, the specific epigenetic changes occurring during UV exposure, chronological aging, … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 15 Feb 2026 · 1,461 accessesView PDF Cite

Review ArticleOpen accessIn the abstractDrought and Terminal Heat Stress Effects and Its Management on Wheat Genotypes: A ReviewSantosh Gupta, Prabin Kumar Mahato, Naresh Upadhyaya et al.Wheat (Triticum aestivum) is a vital cereal crop that plays a crucial role in global food security, supplying essential calories and protein to over 80% of the world's population. In recent decades, the effects of climate change, particularly rising temperatures, have raised concerns about Wheat production worldwide. The optimal daytime temperature for Wheat growth during its reproductive stage is around … …American Journal of Agricultural and Biological Sciences, Vol. 19, Issue 1 · 21 Nov 2024 · 8,233 accessesView PDF Cite

Research ArticleOpen accessIn the abstractCross Talk between Iron Regulatory Proteins and Proinflammatory Molecules in Ovarian Cancer Patients Based on Menopausal StatusHaritha Padannapurath Manoj, Sudha Kuthethur, Reshma Kumarchandra et al.Micronutrient iron is postulated to contribute to the initiation of cancer mainly by the formation of Reactive Oxygen Species (ROS), the key signaling molecules of inflammatory reactions. Iron may also cause elevation of MMP9, a gelatinase responsible for remodeling extracellular matrix in cancer cells through the ROS pathway. Estrogen the hormone which decreases markedly in post menopause is also known … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 31 May 2024 · 4,494 accessesView PDF Cite

Research ArticleOpen accessIn the abstractDifferential Gene Expression of Peroxide Resistant Protein (AhpC) in Planktonic and Biofilm State of Uropathogenic Escherichia coli CellsOmar Sadik Shalal, Ani-Simona SevastreThe gastrointestinal tract seems to be the primary reservoir of Uropathogenic Escherichia coli (UPEC) in humans. UPEC strains harbor the Urinary Tract (UT) and cause Urinary Tract Infections (UTI) which might represent a serious threat to human life. To counteract with the damage caused by the Reactive Oxygen Species (ROS), bacterial strains produce various enzymes and proteins like Alkyl hydroperoxide … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 3 · 13 Oct 2023 · 5,328 accessesView PDF Cite

Research ArticleOpen accessIn the abstractThe Bioaccumulation and Detoxification Mechanism of Neodymium on the Shoot of Rice SeedlingsKailun Shi, Cheng Kun Liu, Keliang Lyu et al.Neodymium (Nd) potentially pollutes environment for its wide usage in agriculture and industry. In this study, the chemical forms of Nd and effect of Nd on rice shoots were studied after rice seedlings were exposed with 0, 1, 10, 100 and1000 μM Nd. The higher concentration of Nd inhibited shoot growth, but the lower concentration of Nd induced shoot growth. … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 2 · 11 Apr 2021 · 6,294 accessesView PDF Cite

Review ArticleOpen accessIn the abstractDisinfection of Water using Supported Titanium Dioxide PhotocatalystsShamkumar Pandurang Deshmukh, Dattatray Krishna Dalavi, Yuvaraj Mohan HungeTiO2 based photocatalyst has potential material for disinfection of harmful pathogens as well as removal of organic compounds. The formation of reactive oxygen species is a key part for overall process but aggregation and band gap constraint explore a new dimension to use of support for propounding its physicochemical properties. Therefore, the modification of TiO2 using various support alters photocatalytic … …American Journal of Engineering and Applied Sciences, Vol. 13, Issue 4 · 28 Dec 2020 · 7,266 accessesView PDF Cite

Research ArticleOpen accessIn the abstractComparative Effects and Phytotoxicity of Photo Fenton Solutions and Acid Rains on Cucumber (Cucumis Sativus) Plants: Treats and ConsoleFawzy Eissa, Sayuri Bandai, Nour El-Hoda Zidan et al.The Eco-physiological assessments of variable parameters known to be essential for proper plant growth and health were determined in cucumber plants exposed to short term treatments in 42 days using two broad classification types; Photo Fenton solution generating OH radicals and simulated acids. Solutions containing different classification of scavengers of OH radicals and mannitol were employed as Controls. Results indicated … …American Journal of Environmental Sciences, Vol. 16, Issue 2 · 21 May 2020 · 6,979 accessesView PDF Cite

Research ArticleOpen accessIn the abstractInhibition Effect of Walnut Leaf Polysaccharide on HepG2 Cells in vitroShuqing Yang, Haifang Xiao, Shuyan Yu et al.In this study, the effect of Walnut Leaf Polysaccharides (WLP) on human liver tumor HepG2 cells was investigated. The results showed that WLP had dose-dependent and time-dependent inhibitory effects on HepG2 cell viability. Typical apoptosis characteristics were observed in WLP-treated HepG2 cells through 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethyl-benzimidazolyl-carbocyanine iodide (DAPI) staining and Acridine Orange (AO)/Ethidium Bromide (EB) dual staining. Meanwhile, significant decrease in Mitochondrial … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 4 · 29 Oct 2019 · 7,316 accessesView PDF Cite