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113 articles for “protein expression”
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Research ArticleOpen accessIn the keywordsProduction of Recombinant Proteins in Insect CellsChristian Kollewe, Andreas VilcinskasAmong the wide range of methods and expression hosts available for the heterologous production of recombinant proteins, insect cells are ideal for the production of complex proteins requiring extensive post-translational modification. This review article provides an overview of the available insect-cell expression systems and their properties, focusing on the widely-used Baculovirus Expression Vector System (BEVS). We discuss the different strategies … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 3 · 21 Sep 2013 · 13,742 accessesView PDFCite
Research ArticleOpen accessIn the keywordsTolemerase Reverse Transcriptase Gene Expression as a Tumor Marker for Hepatocellular CarcinomaM. Magdi Atta, Naglaa Al-Toukhy, Omnia Al-Said et al.Problem statement: Hepatocellular carcinoma will emerge as a major form of malignancy in the coming decades. The continuing high incidence of hepatocellular carcinoma, suggests that this disease will continue to represent a global health problem far into the future. Different genes encode for the various components of the human telomerase complex. These components include the human Telomerase RNA Component (hTERC) … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 2 · 3 Aug 2011 · 7,905 accessesView PDFCite
Research ArticleOpen accessIn the abstractInverse Correlation Between α-Klotho and Diabetic Biomarkers in Type 2 Diabetes: A Cross-Sectional StudyYaser A.M Sulaiman, Moayad M. Al Anzy, Omeed Akbar Ali, Adnan M. IsmailEvidence suggests a link between diabetes and Klotho protein, demonstrated by reduced Klotho gene expression in individuals with diabetes, α- klotho the potential modulator of kidney health in DM. Klotho is primarily expressed in the kidneys and has an anti-inflammatory and antioxidant role, which may protect against the pathological processes that damage renal function in diabetes. Research conducted in Japan … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 2 Jul 2026 · 837 accessesView PDFCite
Research ArticleOpen accessIn the abstractComparative Analysis of Proteins in Two Typical Chinese Thin-Shell WalnutsXu Meng, Tian YilingThis study compared functional properties and molecular characteristics of proteins from two thin-shelled walnut (Juglans regia L.) cultivars predominantly grown in China: Wen 185 and Lvling. Wen 185 walnut protein demonstrated significantly superior performance compared to Lvling across multiple functional parameters, including solubility, emulsifying capacity, foaming capacity, water absorption, and oil absorption. Molecular weight distribution analysis revealed that both proteins … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 15 Feb 2026 · 1,481 accessesView PDFCite
Research ArticleOpen accessIn the abstractDihydroartemisinin Attenuates HBV-Induced Proliferation and Migration in LO2 cells via EMT Pathway ModulationYingde Nong, Caifang Ma, Wei Huang et al.Dihydroartemisinin (DHA), a derivative of artemisinin, possesses well-documented anti-inflammatory properties. This study investigated the inhibitory effects of DHA on hepatitis B virus (HBV)-induced cellular alterations in LO2 cells and elucidated underlying molecular mechanisms. Serum interleukin-6 (IL-6) levels were measured in HBV patients and analyzed for correlations with HBsAg, anti-HBs, and HBeAg. In vitro, LO2 cells were infected with clinical HBV … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 8 Jan 2026 · 2,071 accessesView PDFCite
Research ArticleOpen accessIn the abstractSignal Pathway Regulation in Mammalian Cells in Wireless Communication EnvironmentShengdong LiTo regulate the signal pathway in mammalian cells in a wireless communication environment, an LED light stimulation system has been designed and constructed. To avoid interference from too many data lines, a wireless communication mode has been employed. In this study, HeLa cells and Drosophila melanogaster cells are used as the research objects. The CRY2/CIBN light genetic element system is … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 24 Nov 2025 · 2,001 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Atorvastatin on Oxidized Low-Density Lipoprotein-induced Proliferation, Apoptosis, and Matrix Metalloproteinase-9 Expression in Human MacrophagesBensheng Liu, Huifan Li, Yan Wang, Li ZhangAtorvastatin (ATV), an HMG-CoA reductase inhibitor, is utilized in the treatment of atherosclerotic diseases. Mononuclear Macrophages (MMs) are critical immune cells involved in atherosclerosis progression, participating in processes such as foam cell formation, cytokine secretion, and the development of fibrous cap and lipid core. To further elucidate the mechanism by which ATV exerts its therapeutic effects on atherosclerosis through the … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 18 Nov 2025 · 2,133 accessesView PDFCite
Review ArticleOpen accessIn the abstractFrom Health to Disease: Functional Insights of Scavenger Receptor Class B Type I in Lipid Metabolism and Disease PathogenesisSujina Simon Sailet, Poornima Ajay Manjrekar, Santosh Rai et al.Scavenger receptor class B type I (SR-B1) has caught considerable interest among the scientific community due to its pivotal role in several biological and pathological processes. It is a multifunctional integral membrane protein and multiligand receptor encoded by the SCARB1 gene. SR-B1 has a wide distribution, primarily in the liver as well as steroidogenic organs including the gonads and adrenal … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 11 Jul 2025 · 3,667 accessesView PDFCite
Research ArticleOpen accessIn the abstractInvestigation of the Contribution of Late Embryogenesis Abundant (LEA) K Peptide in Enhancing the Expression of Lipase from Sphingobacterium sp.: In vitro and in Silico StudiesIbrahim Muhammad et al.Sphingobacterium sp. AB3 lipase is a psychrophilic enzyme with optimal lipolytic activity at pH 7 and 15°C. The cold-adapted properties of the lipase render it suitable for various low-temperature industrial applications such as biodiesel production, detergent formulation, and non-thermal food processing. Recent studies have shown that co-expression of LEA K peptide with AB3 lipase resulted in enhanced protein expression in … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 4 · 21 Nov 2024 · 4,569 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Impact of Di-2-Ethylhexyl Phthalate (DEHP) in Focus on the Reproductive System and Toxicity in Rat or Mammalian ModelVenkataramanaiah Poli, Srinivasulu Reddy MotireddyAbsalan, F., Saremy, S., Mansouri, E., Moghadam, M. T., Moghadam, A. R. E., & Razie, G. (2016). Effects of Mono-(2-Ethylhexyl) Phthalate and Di-(2-Ethylhexyl) Phthalate Administrations on Oocyte Meiotic Maturation, Apoptosis and Gene Quantification in Mouse Model. Cell Journal, 18(4), 503–513. https://doi.org/10.22074/cellj.2016.4717 Acevedo‐Rodriguez, A., Kauffman, A. S., Cherrington, B. D., Borges, C. S., Roepke, T. A., & Laconi, M. (2018). Emerging … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 6 Jun 2024 · 12,990 accessesView PDFCite