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128 articles for “proliferation”
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Research ArticleOpen accessIn the abstractImmunomodulatory and Antioxidant Activities of Selenium-Enriched Polysaccharides from Epimedium and Isatis IndigoticaRui Zhang, Jin Li, Jiajia ZhouThis study aims to investigate the effects of selenium modification on polysaccharides derived from two traditional Chinese medicinal herbs-Epimedium (Yinyanghuo) and Isatis root (Banlangen)-in enhancing immune function and antioxidant activity. The purpose is to explore the relationship between structure and function, providing a theoretical basis for the development of efficient plant-based functional antioxidants. Polysaccharides were extracted using an optimized enzymatic … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 3 Feb 2026 · 1,933 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Impact of Di-2-Ethylhexyl Phthalate (DEHP) in Focus on the Reproductive System and Toxicity in Rat or Mammalian ModelVenkataramanaiah Poli, Srinivasulu Reddy MotireddyAbsalan, F., Saremy, S., Mansouri, E., Moghadam, M. T., Moghadam, A. R. E., & Razie, G. (2016). Effects of Mono-(2-Ethylhexyl) Phthalate and Di-(2-Ethylhexyl) Phthalate Administrations on Oocyte Meiotic Maturation, Apoptosis and Gene Quantification in Mouse Model. Cell Journal, 18(4), 503–513. https://doi.org/10.22074/cellj.2016.4717 Acevedo‐Rodriguez, A., Kauffman, A. S., Cherrington, B. D., Borges, C. S., Roepke, T. A., & Laconi, M. (2018). Emerging … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 6 Jun 2024 · 12,990 accessesView PDFCite
Research ArticleOpen accessIn the abstractMechanism Analysis of Artemisinin and Artesunate as Lung Cancer Therapy Agents Through in Silico MethodDidik Harmoko, Vivitri Dewi Prasasty, Adi YulandiSeveral in vitro studies have focused on the ability of artemisinin and its derivatives to suppress lung cancer cells, but there are still many biological processes and mechanisms, such as the interactions between the active compounds (ligands) and receptors that are not well understood and require further research. Drug targeting for lung cancer will be more precise and the inhibition … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 15 Feb 2024 · 6,144 accessesView PDFCite
Research ArticleOpen accessIn the abstractPotential of Fig Leaf (Ficus carica L.) as Immunomodulatory Agent in vitro and in SilicoAnita Dewi, Fitri Rahmayanti, Haidar Bagir et al.Natural remedies are increasingly being used as alternatives to conventional medicine, and their popularity is growing. The fig plant (Ficus carica L.), which is known to contain secondary metabolites such as alkaloids, flavonoids, phenolics, terpenoids, steroids, and saponins, has the potential to act as an immunomodulator. The purpose of this study was to determine the content of flavonoid compounds based … …OnLine Journal of Biological Sciences, Vol. 23, Issue 1 · 19 Jan 2023 · 6,232 accessesView PDFCite
Research ArticleOpen accessIn the abstractRadiation Triggered Phenotypic Changes of Regulatory T CellsLantao Liu, Yan Peng, Deqin Zhang, Dongsheng NiuIonizing radiation disrupts the immune balance easily. Regulatory T (Treg) cells directly affect the immune balance after radiation exposure. Meanwhile, the present study is to investigate the survival ability and phenotypic changes of Treg cells induced by 60Co γ-rays in order to expand the understanding on how Treg cells modulated by radiation. Mice lymphocytes were isolated from thymus and spleen … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 1 · 20 Mar 2022 · 5,828 accessesView PDFCite
Research ArticleOpen accessIn the abstractArabic Fake News Detection Across Generational Text Representations: From Traditional Models to Transformer-Based MethodologiesNoor M. AlkudahThe rapid proliferation of fake news on Arabic social media has amplified societal and political risks, yet research on automatic detection in Arabic remains limited due to scarce datasets, morphological complexity, and underexplored preprocessing strategies. This study presents a comprehensive benchmark for Arabic fake news detection, unifying seven Machine Learning (ML) algorithms, three Deep Learning (DL) models, and a transformer-based … …Journal of Computer Science, Vol. 22, Issue 4 · 17 Apr 2026 · 1,873 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunomodulatory and Antioxidant Effects of Stachys Japonica Miq. Ethanol Extract on Cyclophosphamide-Induced Immunosuppressed Mice and its Phytochemical CompositionXueping Jiang, Jianglong He, Yanjun Chen, Fang WangStachys japonica Miq. is an edible wild botanical drug and a traditional medicine in China. This study focused on examining the phytochemical profile and antioxidant properties of the ethanol extract of S. japonica Miq (SJEE) in vitro, as well as its immunomodulatory and antioxidant activities in cyclophosphamide (Cy)-induced immunosuppressed mice. The SJEE was analysed by UPLC-HRMS/MS. 36 Polyphenols, including flavonoids, … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 1 · 13 Apr 2026 · 1,449 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Hybrid Grey Wolf Optimizer and Deep Transfer Learning-Based Intrusion Detection System for IoTKapil Shrivastava, Manish Tiwari, Prasun ChakrabartiThe rapid proliferation of Internet of Things (IoT) devices has driven significant advancements in connectivity and automation, but it has also introduced substantial cybersecurity risks, including intrusions and cyberattacks. To address these challenges, this study proposes a hybrid intrusion detection framework that combines advanced optimization techniques with ensemble deep learning to enhance detection accuracy and computational efficiency. The proposed framework … …Journal of Computer Science, Vol. 22, Issue 2 · 17 Feb 2026 · 1,506 accessesView PDFCite
Review ArticleOpen accessIn the abstractDeepfake Technology: A Comprehensive Review of Trends, Applications, Ethical Concerns, and ChallengesBattula Thirumaleshwari Devi, Rajkumar RajasekaranThe digital age has fundamentally transformed how information is created and disseminated, raising critical concerns about the authenticity and trustworthiness of online content. Recent advances in Artificial Intelligence (AI), particularly deep learning, have given rise to deepfakes: highly realistic synthetic media generated by manipulating or replacing faces, voices, and actions in videos. While deepfake technology offers innovative applications across various … …Journal of Computer Science, Vol. 22, Issue 1 · 17 Feb 2026 · 4,861 accessesView PDFCite
Research ArticleOpen accessIn the abstractIncorporation of Modified Region Growing into FCM Clustering for Extraction of Tumors in MR ImagesLovepreet Singh Brar, Jaget Singh, Bhawana Agrawal et al.Due to the tremendous growth of medical Magnetic Resonance (MR) images, it becomes an essential requirement for an automated extraction of diagnostically salient parts of the images to refine the transmission and storage process. Research method: This paper proposes an automated unsupervised machine learning segmentation technique named fuzzy c-means clustering based on modified region growing algorithm (RG-FCM) for the extraction … …Journal of Computer Science, Vol. 21, Issue 12 · 12 Feb 2026 · 1,477 accessesView PDFCite