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59 results for “polymorphisms”
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Research ArticleOpen accessEvery word in the titleLack of Association of Glutathione S-transferase Gene Polymorphisms in Iranian Prostate Cancer SubjectsB. Sahar Ansari, R. Vasudevan, M. Mirinargesi et al.Problem statement: Glutathione S-transferase is super family genes that encode enzymes which involve in the detoxification of the cell and protects DNA from damage. Conflicting results was found in several studies in association with GSTT1 and GSTM1 gene polymorphisms and prostate cancer. In this study, we determined the association between the GSTT1 and GSTM1 gene polymorphism and prostate cancer in … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 1 · 31 Mar 2009 · 8,273 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Frequency of Polymorphisms affecting Lead and Mercury Toxicity among Children with AutismShannon Rose, Stepan Melnyk, Alena Savenka et al.Individual risk of developmental neurotoxicity with exposure to environmentally relevant levels of lead and mercury is likely to be determined by genetic susceptibility factors as well as additive interactions with other environmental pollutants, cumulative dose, and the developmental stage of exposure. The apparent increase in autism diagnosis over the last 15 years has enhanced interest in the possibility that an … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 7,521 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEstimating the Genetic Polymorphisms of Gujarat Population using 17 Y Chromosomal STR lociAditi Mishra, Ulhas Gondhali, Sumit ChoudharyThe present study aims to report genetic variations in unrelated male (n = 118) of the Gujarat population with the help of seventeen Y-STR markers (DYS456, DYS389I, DYS390, DYS389II, DYS458, DYS19, DYS385a/b, DYS393, DYS391, DYS439, DYS635, DYS392, Y GATA H4, DYS437, DYS438 and DYS448). Allele frequencies and forensic parameters were calculated. A total of 96 distinct alleles were reported with … …OnLine Journal of Biological Sciences, Vol. 21, Issue 2 · 23 Jun 2021 · 6,504 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleGenetics Polymorphisms of INHA in Local Goat Populations in South-West Sulawesi Region of IndonesiaMuhammad Ihsan Andi Dagong, Sri Rachma Aprilita Bugiwati, Lellah Rahim, Nurul PurnomoInhibin subunit alpha (INHA) is one important gene that control reproductive characteristics of animal. The aim of this research was to identify the genetic diversity of INHA gene of Kacang and Peranakan Etawa (PE) goat as local goat breed which were maintained by farmers at goat development centers in Sulawesi region, Indonesia. DNA samples were collected from 137 heads Kacang … …American Journal of Animal and Veterinary Sciences, Vol. 15, Issue 1 · 12 Mar 2020 · 7,273 accessesView PDFCite
Research ArticleOpen accessEvery word in the titlePolymorphisms in Several Porcine Genes are Associated with Growth TraitsGetmantseva Lyubov, Anatoly Kolosov, Maria Leonova et al.The purpose of this study was to confirm the relation between polymorphism of POU1F1, GH, PRLR and MC4R genes and economically important traits of the Duroc pigs bred in Russia. Studies were carried out on purebred Duroc breed pigs (male n = 360). All pigs were kept under identical and standard conditions. The traits of analysis: The number of Days … …American Journal of Animal and Veterinary Sciences, Vol. 11, Issue 4 · 12 Nov 2016 · 7,415 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleGenetic Polymorphisms in the Fat Mass and Obesity-Associated Gene Confers Risk of Obesity in Iraqi PopulationShatha Ramadhanzaidan, Faris Abd Al Kareem, Lujain Anwar AlkhazrajyProblem statement: Obesity is strongly influenced by genetic factors, with an estimated heritability of 60% BMI. Genetic susceptibility to the common form of obesity appears to be polygenic. Although theoretical analyses emphasized the power of genetic association study in common polygenic diseases, the search for genes conferring the risk of obesity has thus far not been very successful. Approach: In … …American Journal of Infectious Diseases, Vol. 7, Issue 2 · 21 Sep 2011 · 7,622 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEffectiveness of the Use of Genetic Markers of Meat Productivity in the Kazakh White-Headed Breed Identified Using Genome-Wide Association StudyIndira Beishova, Askar Nametov, Alzhan Shamshidin et al.The study aimed to determine the effectiveness of the use of genetic markers in cattle of the Kazakh white-headed breed identified using a genome-wide association study. The object of the study was the livestock of 790 Kazakh white-headed bulls bred in breeding farms of the Republic of Kazakhstan. The study adheres to rigorous ethical standards, with all procedures approved by … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 25 Jun 2024 · 5,023 accessesView PDFCite
Review ArticleOpen accessIn the keywordsVascular Endothelial Growth Factor: An Overview Across Multiple Disease ConditionsMiriam CanaveseVascular Endothelial Growth Factor (VEGF) is the major player in the regulation of physiological angiogenesis as well as it has also been implicated in pathological angiogenesis, associated with cancers and other conditions, among which psoriasis, autoimmune diseases and visual loss in macular degeneration. Interestingly, three regulatory Single Nucleotide Polymorphisms (rSNPs) in the promoter region of VEGF-A gene have been significantly … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 1 · 6 May 2015 · 7,099 accessesView PDFCite
Research ArticleOpen accessIn the keywordsOverdominance Effects between Malaria and Visceral Leishmaniasis in the 5q31 RegionMutaz Amin, Abdelbadea Elhassan, Kirk Rocket, Muntasir IbrahimA group of SNPs in 5q31, genotyped from Hausa tribe of Koka village in eastern Sudan; an area endemic with malaria and visceral leishmaniasis, were analyzed by The Leishmaniasis research group and found to have significant excess of heterozygosis level and departure from HWE and assumed to be due to natural selection resulting from notorious deadly outbreaks since various ethnic … …OnLine Journal of Biological Sciences, Vol. 15, Issue 4 · 18 Sep 2015 · 7,114 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAFLPs in Warmblood Sporting Horses: Genetic Correlation with Height at the WithersV. Sanchez, C. Lemus, A. Inchaustegui et al.The Mexican army produces Warmblood horses for jumping proposes. However, breeding is based on phenotype and stallions are selected stepwise until the end of growth, representing a high care and maintenance cost. In this work using 64 selective primer combinations and AFLP technology we identified specific molecular markers related with height at the withers measurements of Warmblood horses. AFLPs generated … …American Journal of Infectious Diseases, Vol. 3, Issue 2 · 30 Jun 2007 · 6,753 accessesView PDFCite