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35 results for “pivotal role”
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Research ArticleOpen accessIn the abstractUnfair Reviews Detection on Amazon Reviews using Sentiment Analysis with Supervised Learning TechniquesElshrif Ibrahim Elmurngi, Abdelouahed GherbiReputation and trust are significantly important and play a pivotal role in enabling multiple parties to establish relationships that achieve mutual benefit especially in an E-Commerce (EC) environment. There are several factors negatively affecting the sight of customers and sellers in terms of reputation. For instance, lack of credibility in providing feedback reviews, by which users might create phantom feedback … …Journal of Computer Science, Vol. 14, Issue 5 · 14 May 2018 · 9,889 accessesView PDFCite
EditorialOpen accessIn the abstractFocalize the Structure of Myd88 in TLR Signaling Pathway to Modulate Innate Immune Response: New Target for Old DiseasesShuai Xing, Ping ZhouAll diseases have their Achilles’ Heel to target and this is especially true for immunorelated diseases which must be treated by targeting the immune system somewhere and somehow correctly. In the most recent decade, immunologists recognized that the Toll-Like Receptor (TLR) signaling pathway in innate immune system plays a double-edged role in the pathogenesis of many notorious diseases. Although the … …American Journal of Immunology, Vol. 13, Issue 3 · 6 Sep 2017 · 7,865 accessesView PDFCite
EditorialOpen accessIn the abstractUse of Design of Experiments and Manuscripts Rejection RateAydin Berenjian, Jason RyanTraditional one-variable-at-a-time method was and still is for some researchers, the general procedure to determine the optimal conditions for a chemical, biochemical or biological mechanism. According to this technique, a large number of experiments should be performed to obtain a high precision in effect assessment and also the interaction among the variables cannot be defined. To overcome the limitations of … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 2 · 8 Jun 2015 · 7,174 accessesView PDFCite
EditorialOpen accessIn the abstractGLUTATHIONE: A POSSIBLE LINK TO AUTOPHAGY IN SYSTEMIC LUPUS ERYTHEMATOSUSDilip Shah, Swapan K. NathIncreased free radical formation and altered redox state are of fundamental importance in the pathogenesis of autoimmune diseases including Systemic Lupus Erythematos (SLE). Free radicals are mainly derived from oxygen (Reactive Oxygen Species/ROS) and nitrogen (Reactive Nitrogen Species/RNS) at mitochondria, cellular membranes and the endoplasmic reticulum membrane as physiological responses to a variety of internal and external stress (Shah et … …American Journal of Immunology, Vol. 10, Issue 3 · 3 Sep 2014 · 12,777 accessesView PDFCite
Research ArticleOpen accessIn the abstractCASE STUDY OF THE OPTIMIZING THE AUTOMOTIVE MANUFACTURING SYSTEMS EFFICIENCY VIA APPLYING NEW METHOD OF SCHEDULINGSeyedehfarzaneh Nojabaei, Matthew FranchettiEfficiency is becoming a pivotal aspect in each manufacturing system and scheduling plays a crucial role in sustaining it. The applicability of distributed computing to coordinate and execute jobs has been investigated in the past literature. Moreover, it is significant that even for sensitive industrial systems the only criterion of allocating jobs to appropriate machines is the FIFO policy. On … …American Journal of Engineering and Applied Sciences, Vol. 7, Issue 2 · 8 Jul 2014 · 7,426 accessesView PDFCite
Research ArticleOpen accessIn the abstractLOW FOOTPRINT HIGH INTELLIGIBILITY MALAY SPEECH SYNTHESIZER BASED ON STATISTICAL DATALau Chee Yong, Tan Tian SweeSpeech synthesis plays a pivotal role nowadays. It can be found in various daily applications such as in mobile phones, navigation systems, languages learning software and so on. In this study, a Malay language speech synthesizer was designed using hidden Markov model to improve the performance of current Malay speech synthesizer and also extend Malay speech technology. Statistical parametric method … …Journal of Computer Science, Vol. 10, Issue 2 · 19 Nov 2013 · 6,725 accessesView PDFCite
Research ArticleOpen accessIn the abstractE-Learning Initiative Capacity Building for Healthcare Workforce of Developing CountriesNurhizam Safie, Syed AljunidThis study aims to explicate the strategic utilisation of e-learning is of upmost significance as e-learning plays a pivotal role in the improvement of healthcare learning and knowledge transfer, especially in developing countries and in pursuing of Millennium Development Goals (MDGs). Rapid technology changes in the learning and knowledge transfer landscape markedly, the swift pace of e-learning leaving healthcare providers … …Journal of Computer Science, Vol. 9, Issue 5 · 23 May 2013 · 7,765 accessesView PDFCite
Research ArticleOpen accessIn the abstractCardiotrophin-1 in Patients with Acute Myocardial InfarctionAbdolreza Sotoodeh Jahromi, Mohammad Shojaie, Abdoulhossain MadaniProblem statement: Myocardial infarction is the combined result of environmental and personal factors. Prothrombotic factors might play an important role in this phenomenon. Inflammation plays a pivotal role in atherosclerosis and coronary heart disease. Cardiotrophin-1 (CT-1), a member of the IL-6 family of cytokines, was identified as a growth factor for cardiac myocytes that induces cardiomyocyte hypertrophy and stimulates cardiac … …American Journal of Applied Sciences, Vol. 7, Issue 9 · 30 Sep 2010 · 7,243 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Exercise Training on Adiponectin Receptor Expression and Insulin Resistance in Mice Fed a High Fat DietNaglaa Fathy Alhusseini, Nasr Arafat Belacy, Enas Mohammed Kasem, Mona Maher AllamProblem statement: Adiponectin is an adipocyte secreted hormones, exerts its effects via the specific receptors. AdipoR1 and adipoR2 and plays a pivotal role in lipid and glucose metabolism. Approach: We investigated the effect of increased physical activities on insulin resistance and if this effect is modulated through adiponectin receptor expression. Results: We also assessed the effect of High Fat Diet … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 2 · 30 Jun 2010 · 9,956 accessesView PDFCite
Research ArticleOpen accessIn the abstractGenomic Distance between Thymidylate Synthase and Dihydrofolate Reductase Genes Does Not Correlate With Phylogenetic Evolution in BacteriaVitor Hugo MoreauProblem statement: Dihydrofolate Reductase (DHFR) and Thymidylate Synthase (TS) exist as bifunctional enzymes coded into unique polypeptide chain in protozoans. Bifunctional DHFR-TS is associated with an increase in the enzymatic activity by channeling the substrate between the active sites. In some bacteria, DHFR and TS genes are neighbors in the genome, whereas in others, they are located millions of base … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 1 · 31 Mar 2010 · 8,196 accessesView PDFCite