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196 results for “oxidative”
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Research ArticleOpen accessEvery word in the titleMoringa Oleifera Lam Mitigates Oxidative Damage and Brain Infarct Volume in Focal Cerebral IschemiaWoranan Kirisattayakul, Jintanaporn Wattanathorn, Terdthai Tong-Un et al.Problem statement: At present, the therapeutic outcome of cerebral ischemia is still not in the satisfaction level. Therefore, the preventive strategy is considered. Based on the protective effect against oxidative damage of Moringa oleifera Lam. Leaves extract, we hypothesized that this plant extract might protect against cerebral ischemia, one of the challenge problems nowadays. In order to test this hypothesis, … …American Journal of Applied Sciences, Vol. 9, Issue 9 · 3 Aug 2012 · 7,574 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleVitamin C Alleviates Chronic Chlorpyrifos Induced Alterations in Serum Lipids and Oxidative Parameters in Male Wistar RatsS. F. Ambali, M. Shittu, J. O. Ayo et al.Problem statement: Although the increase incidence of cardiovascular diseases, obesity and diabetes mellitus has been attributed to changing life style, the role of environmental contaminants is currently being given considerable attention. Pesticides, including Organophosphate (OP) insecticides are one of the most pervasive environmental contaminants that are deliberately released into the environment. Chlorpyrifos (CPF), a widely used OP insecticide has been … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 4 · 21 Feb 2012 · 7,576 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleHepatoprotective Effect of Taurine Against Oxidative Stress Due to Methotrexate in RatE. Issabeagloo, M. Taghizadiyeh, P. KermanizadehProblem statement: Taurine, 2-aminoethanesulphonic acid is an essential amino acid. It is present at high concentrations in many tissues. It plays important roles in numerous physiological functions including conjugation with bile acids, modulation of calcium levels and maintenance of osmolarity, antioxidation and stabilization of membranes. Methotrexate (MTX), as the most disease modifying anti-rheumatic drug used for Rheumatoid Arthritis (RA), has … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 4 · 16 Jan 2012 · 8,495 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleVitamin E Mitigates Chronic Chlorpyrifos-Induced Oxidative Changes in Pituitary Glands and Testes in Wistar RatsM. Shittu, J. O. Ayo, S. F. Ambali et al.Problem statement: The sperm counts of men have declined by about 50% in the last few decades. The contribution of environmental contaminants to this decline cannot be overemphasized. Pesticide is one of the most pervasive environmental chemical contaminants that have been of increased use due to the compelling need to feed the ever-growing world human and animal population and protect … …American Journal of Applied Sciences, Vol. 9, Issue 1 · 19 Nov 2011 · 7,309 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEffect of Garcinia Atroviridis on Oxidative Stress and Atherosclerotic Changes in Experimental Guinea PigsAdel. A. Amran, Zaiton Zakaria, Faizah Othman, Paden MoratProblem statement: Oxidative stress plays a major role in hypercholesterolemia induced atherosclerosis. Garcinia atroviridis has been shown to exhibit antioxidant properties. Approach: The present study aimed to investigate the effect of Garcinia atroviridis on the oxidative stress in guinea pigs fed with high cholesterol diet. Twenty-four male Guinea pigs were divided into four groups. Group I served as control while … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 2 · 30 Jun 2010 · 9,035 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCamel's Milk Protects Against Cadmium Chloride-Induced Hypocromic Microcytic Anemia and Oxidative Stress in Red Blood Cells of White Albino RatsMohammad DallakProblem statement: Cadmium is a heavy metal of wide occupational and environmental contamination. In recent years, however, Cadmium has been implicated in the pathogenesis of several clinical disorders. One of the most frequently described problems in aluminum toxicity is anemia. Therefore, the present study was carried out to determine the effectiveness of Camel's milk in alleviating the toxicity of Aluminum … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 4 · 31 Dec 2009 · 8,683 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCamel's Milk Alleviates Oxidative Stress and Lipid Peroxidation Induced by Chronic Aluminum Chloride Exposure in Rat's TestesFahaid H. Al-HashemProblem statement: The present study was carried out to examine the effectiveness of Camel’s milk in alleviating aluminum chloride (AlCl3)-induced oxidative stress and lipid peroxidation in rat testes. Approach: White albino male rats (230-250 g) were divided into three groups of 10 rats: A control group, treated with normal saline and two experimental groups, the AlCl3 treated group and the … …American Journal of Applied Sciences, Vol. 6, Issue 11 · 30 Nov 2009 · 7,429 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleOxidation of Exogenous Lactate by Lactate Dehydrogenase C in the Midpiece of Rat Epididymal Sperm is Essential for Motility and Oxidative ActivityHideaki Yamashiro, Masaaki Toyomizu, Akane Kadowaki et al.Problem statement: To identify the metabolic reaction-glycolysis or oxidative phosphorylation that is mainly involved in the production of energy required for rat sperm mobilization. Approach: Epididymal sperm were collected from Wistar rats and extended in lactate-containing or lactate-free raffinose-modified Krebs-Ringer Bicarbonate solution (mKRB)-egg yolk medium supplemented with 0, 1, 2, or 3 mM 2-Deoxy-D-Glucose (2 DG) and 1, 2, or … …American Journal of Applied Sciences, Vol. 6, Issue 10 · 31 Oct 2009 · 6,901 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCamel's Milk Protects Against Aluminum Chloride-Induced Normocytic Normocromic Anemia, Lipid Peroxidation and Oxidative Stress in Erythrocytes of White Albino RatsFahaid Al-HashemProblem statement: Aluminum (Al) is an indifferent element from a toxicological point of view. In recent years, however, Al has been implicated in the pathogenesis of several clinical disorders. One of the most frequently described problem in aluminum toxicity is anemia. The present study was carried out to determine the effectiveness of Camel’s milk in alleviating the toxicity of aluminum … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 3 · 30 Sep 2009 · 8,021 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleA Novel Rodent Model of Autism: Intraventricular Infusions of Propionic Acid Increase Locomotor Activity and Induce Neuroinflammation and Oxidative Stress in Discrete Regions of Adult Rat BrainDerrick F. MacFabe, Karina Rodríguez-Capote, Jennifer E. Hoffman et al.Innate neuroinflammatory changes, increased oxidative stress and disorders of glutathione metabolism may be involved in the pathophysiology of autism spectrum disorders (ASD). Propionic acid (PPA) is a dietary and gut bacterial short chain fatty acid which can produce brain and behavioral changes reminiscent of ASD following intraventricular infusion in rats. Adult Long-Evans rats were given intraventricular infusions of either PPA … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 12,613 accessesView PDFCite