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46 results for “over-expression”
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Research ArticleOpen accessIn the abstractP-Glycoprotein-Mediated Efflux and Drug Sequestration in Lysosomes Confer Advantages of K562 Multidrug Resistance Sublines to Survive Prolonged Exposure to Cytotoxic AgentsNathupakorn Dechsupa, Samlee MankhetkornProblem statement: Cellular drug resistance to anticancer agents is major obstacle in cancer chemotherapy and the mechanisms by which these MDR cells possess for protecting themselves to survive prolonged exposure to cytotoxic agents still debating. The study aimed to clarify the role of P-glycoprotein (Pgp) and enhanced drug sequestration in lysosomes to confer the multidrug resistance K562 cells with varied … …American Journal of Applied Sciences, Vol. 6, Issue 9 · 30 Sep 2009 · 7,504 accessesView PDFCite
Research ArticleOpen accessIn the abstractInhibition of Cholesterol Esterification Influences Cytokine Exspression in Lypopolisaccharide-activated P388D1 MacrophagesRosa Rita Bonatesta, Francesca Sanna, Sabrina Uda et al.Several in vivo and in vitro studies have demonstrated the involvement of infectious agents in the development of atherosclerosis. However, the mechanisms by which micro-organisms induce and/or aggravate atherosclerosis, are so far unclear. Accumulation of cholesterol esters and lipid laden cell formation are hallmark of the atherogenesis, however, the possible relationship between cholesterol esterification and the signal-transducing component of LPS … …American Journal of Infectious Diseases, Vol. 3, Issue 3 · 30 Sep 2007 · 7,481 accessesView PDFCite
Research ArticleOpen accessIn the abstractInflammatory Cytokine Expression Patterns in Rat Skin Exposed to JP-8 Jet FuelRandle M. Gallucci, Bethany M. MickleOne of the main complaints of personnel exposed to JP-8 jet fuel is irritant dermatitis. The purpose of this investigation is to describe the JP-8 induced inflammatory cytokine response in skin over various periods of exposure. JP-8 jet fuel or acetone control (300 μL) was applied to the denuded skin of rats once a day for up to seven days. … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 3 · 30 Sep 2006 · 7,042 accessesView PDFCite
Research ArticleOpen accessIn the abstractEmpirical Analysis and Mathematical Representation of the Path Length Complexity in Binary Decision DiagramsA. Assi, P. W.C. Prasad, B. Mills, A. ElchouemiInformation about the distribution of path-lengths in a Binary Decision Diagrams (BDDs) representing Boolean functions is useful in determining the speed of hardware and software implementations of the circuit represented by these Boolean functions. This study presents expressions produced from an empirical analysis of a representative collection of Boolean functions. The Average Path Length (APL) and the Shortest Path Length … …Journal of Computer Science, Vol. 2, Issue 3 · 31 Mar 2006 · 6,814 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Green Tea on Hepatic Cells Under the Influence of Inflammatory Conditions: In Vitro StudyIbrahim G. Saleh, Zulfiqar Ali, Farid M. Hamada et al.The concern about safety of consumption of Green Tea (GT) supplements has become a scope of many studies. We and others have described earlier the effect of the administration of GT and its polyphenols on liver in a mouse model. In this study we aimed to investigate the effect of GT on HepG2 cells. HepG2 cells were treated with different … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 4 · 3 Dec 2013 · 7,314 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnalysis of a Two Unit Standby Oil Delivering System with a Provision of Switching Over to another System at Need to Increase the AvailabilityUpasana Sharma, Rekha, Gulshan TanejaProblem statement: The study deals with a standby system consisting of two units. Initially one unit is operative and the other is standby. When both the units are failed then there is a provision of switching over to the other similar system. This practical situation may be observed in an oil refinery plant. Real data on failure and repair rates … …Journal of Mathematics and Statistics, Vol. 7, Issue 1 · 31 Jan 2011 · 7,107 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnalyzing Public Sentiment on Demonetization Using SVM: A Machine Learning ApproachKaliappan M, Guruprakash B, Rajalakshmi et al.The Indian economy experienced significant disruption following the implementation of demonetization, a policy initiative aimed at eliminating black money, controlling inflation, and promoting financial inclusion. However, this currency ban generated widespread debate and polarized public opinion. This study analyzes public sentiment toward demonetization using social media data, specifically Twitter posts characterized by mixed sentiments, sarcasm, and nuanced linguistic expressions. We … …Journal of Computer Science, Vol. 21, Issue 11 · 18 Dec 2025 · 2,235 accessesView PDFCite
Research ArticleOpen accessIn the abstractSchoenberg Logarithmic Image Similarity in Prewitt-Gabor-Zernike DomainAhmed Jebur Ali, Zahir M. Hussain, Mohammed Sahib Mechee, Zainab Ali KhalafThis paper represents a new approach for face recognition that incorporates Prewitt edge detection, Gabor filter and Zernike moments to transform the image into a unified domain. On this joint domain, five distance metrics are constructed using Schoenberg transform for the purpose of defining efficient similarity measures for holistic face recognition. The proposed Schoenberg similarity applies Schoenberg transform to the … …American Journal of Applied Sciences, Vol. 14, Issue 9 · 28 Sep 2017 · 7,931 accessesView PDFCite
Research ArticleOpen accessIn the abstractIllumina-Based De Novo Transcriptome Analysis and Identifications of Genes Involved in the Monolignol Biosynthesis Pathway in Acacia koaKazue Ishihara, Eric K.W. Lee, Isabel Rushanaedy, Dulal BorthakurAcacia koa is a leguminous timber tree endemic to the Hawaiian Islands. For breeding projects involved in improving wood quality of A. koa, understanding of genes influencing wood quality is crucial. Therefore, the objective of this study was to identify A. koa genes in the monolignol biosynthesis pathway, which is involved in wood formation and development. In this study, whole … …Current Research in Bioinformatics, Vol. 4, Issue 1 · 6 Aug 2015 · 11,037 accessesView PDFCite