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28 articles for “motif”

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Research ArticleOpen accessIn the abstractCpG Oligodeoxynucleotides Debate the Damaging Action of Cisplatin on Immune Cell DNA: A PCR Array Application on Repair Genes ExpressionNaglaa Fathy Alhusseini, Amal Abo El-Fadl, Shabaan Hemada et al.Synthetic Oligodeoxynucleotides (ODN) expressing CpG motifs (CpG-ODN) mimic the immunostimulatory activity of bacterial DNA and are commonly used to activate Toll Like Receptor 9 (TLR9) for therapeutic applications. CpG-ODN can counteract the activity of DNA-damaging chemotherapy and radiation therapy on immune cell and enhance immunity in preclinical mouse models. We hypothesized that these actions of CpG-ODN on immune cells are … …American Journal of Biochemistry and Biotechnology, Vol. 12, Issue 3 · 27 Jul 2016 · 7,625 accessesView PDFCite
Research ArticleOpen accessIn the abstractDevelopment, Polymorphism and Cross-Species Transferability of Genomic SSR Markers in Duabanga Moluccana, an Indigenous Tree Species from SarawakKit-Siong Liew, Wei-Seng Ho, Shek-Ling Pang, Julaihi AbdullahIn this study, we used ISSR-suppression methods to develop a set of SSR markers for Duabanga moluccana. It is an indigenous fast growing tropical tree species. A total of 44 SSR regions were identified and specific primer pairs were designed. The SSR motifs contained perfect compound with 24 (54.5%) occurrences, followed by the imperfect compounds with 8 (18.2%), simple perfect … …OnLine Journal of Biological Sciences, Vol. 16, Issue 1 · 26 Jan 2016 · 7,784 accessesView PDFCite
Research ArticleOpen accessIn the abstractHeterologous Expression and Characterization of Thermostable Levansucrase (BsSacB) from Bacillus subtilis BB03Viniti Vaidya, Gajjeraman Prabu, D. Theertha PrasadThermostable levansucrase encoding gene (sacB) with its promoter was isolated from Bacillus subtilis BB03. BsSacB is composed of 1419 bp, encoding 473 amino acid residues and with promoter regions TTGCAA (-35) and TAGAAT (-10). The amino acid sequence analysis of BsSacB showed conserved motifs of microbial fructosyltransferase belonging to Glycoside Hydrolase family 68 (GH68). Comparative analysis of the protein structure … …OnLine Journal of Biological Sciences, Vol. 15, Issue 1 · 25 Mar 2015 · 7,371 accessesView PDFCite
Research ArticleOpen accessIn the abstractPrevalence of miRNAs in Introns and Cis-Regulatory Regions of Genes of the Somatotropic Axis in MammalsTatiana Shkurat, Dmitry Romanov, Evgeny Pshenichnyy et al.To understand the role of microRNA in genetic control of animal growth mechanisms, we performed bioinformatic analysis of the localization of microRNAs in introns and cis-regulatory regions of the somatotropic axis genes-GH1, GHRH, SST and IGF1 in Homo sapiens, Macaca mulatta, Pan troglodytes, Pongo abelii, Gorilla gorilla, Ovis aries, Bos Taurus, Loxodonta Africana, Oryctolagus cuniculus, Canis lupus, Rattus norvegicus and … …American Journal of Applied Sciences, Vol. 12, Issue 1 · 26 Jan 2015 · 7,015 accessesView PDFCite
Research ArticleOpen accessIn the abstractRendezvous with Tat: Transactivator of Transcription during Human Immunodeficiency Virus PathogenesisSneham Tiwari, Madhavan P.N. Nair, Shailendra K. SaxenaAcquired immune deficiency syndrome is a deadly disease caused by HIV, declared as a global catastrophe engulfing millions of lives per year. It took ~1.8 million lives in the year 2010 alone, as per reports of UNAIDS. HIV-1 is an enveloped retrovirus, having genome composed of two copies of ssRNA. It attacks the T-lymphocytes of the hosts, causes several multifaceted … …American Journal of Infectious Diseases, Vol. 8, Issue 2 · 31 Jul 2012 · 7,625 accessesView PDFCite
Research ArticleOpen accessIn the abstractWorldviews in Isan-Thai StoriesJaruwan Thammawat, Pathom Hongsuwan, Wajuppa TossaProblem statement: This study aimed to investigate two-fold: To present worldviews in Isan-Thai Stories and to explain the connections between the worldviews and their societal contexts. Approach: Following the methodology of folklore studies, both oral and written versions of Isan-Thai stories were analyzed in order to find out their structures, contents, motifs and contexts. The 76 stories which were chosen … …Journal of Social Sciences, Vol. 5, Issue 4 · 31 Dec 2009 · 7,529 accessesView PDFCite
Research ArticleOpen accessIn the abstractNucleotide Sequence of the Coat Protein Gene of the Malaysian Passiflora Virus and its 3' Non-Coding RegionNorzihan Abdullah, Ismanizan Ismail, Vilasini Pillai et al.Problem statement: In this study, we identified the full length Coat Protein (CP) gene of the Malaysian Passiflora Virus (MPV) and its 3' non-coding region. The CP gene of the MPV contained 285 amino acid residues. Approach: Pairwise comparison of the MPV CP region with four other potyviruses, namely East Asian Passiflora Virus (EAPV), Passionfruit Woodiness Virus (PWV), Bean Common … …American Journal of Applied Sciences, Vol. 6, Issue 9 · 30 Sep 2009 · 7,723 accessesView PDFCite
Research ArticleOpen accessIn the abstractHuman Latrophilin-2 is Expressed in the Cytotrophoblast and Syncytiotrophoblast of Placenta and in Endothelial CellsGunda Herberth, Anke Stein, Jens Glienke et al.Latrophilin-2 is a member of the family of adhesion-GPCRs that is characterised by a long N-terminus which contains motifs identified in proteins involved in cell adhesion. We were interested in determining the expression pattern of human latrophilin-2 and to perform a biochemical characterisation of this protein. The expression pattern of latrophilin-2 was analysed in human organs, tissues and cell lines. … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 3 · 30 Sep 2005 · 8,053 accessesView PDFCite