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29 articles for “modulator”
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Review ArticleOpen accessIn the abstractRole of Cytokines and Transcription Factors in Periodontitis: A Review of Cellular and Molecular MechanismsAnne Carolina Eleutério Leite, Valéria Martins de Araújo Carneiro, Júlia Faria Nunes et al.Periodontal Diseases (PD) are characterized by pathological manifestation of host immune response to bacterial infection at the tooth/gingival interface. Evidences points periodontitis as a risk factor for pathological systemic conditions, such as, cardiovascular diseases and diabetes. The identification of host factors that determine their susceptibility to immune subversion can provide useful information in the pathogenesis of periodontitis. Protective acute inflammatory … …American Journal of Immunology, Vol. 11, Issue 4 · 9 Dec 2015 · 7,807 accessesView PDFCite
EditorialOpen accessIn the abstractAre Heat Shock Proteins Druggable Candidates?Tawanda Zininga, Addmore ShonhaiBanumathy, G., V. Singh, S.R. Pavithra and U. Tatu, 2003. Heat shock protein 90 function is essential for Plasmodium falciparum growth in human erythrocytes. J. Biol. Chem., 278: 18336-18345. DOI: 10.1074/jbc.M211309200 Brehmer, D., S. Rudiger, C.S. Gassler, D. Klostermeier and L. Packschies et al., 2001. Tuning of chaperone activity of Hsp70 proteins by modulation of nucleotide exchange. Nature Structural Molecular … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 4 · 2 Dec 2014 · 8,166 accessesView PDFCite
Research ArticleOpen accessIn the abstractTrace Elements Distribution in the Brain of Stressed RatsZerrouk Kamal, Mohamed Najimi, Mohammed Chigr et al.Because of their ability to modulate the Gamma Aminobutyric Acid (GABA) a receptor complex, the principal aim of the current work is to assess two essential heavy metals: Iron (Fe) and zinc (Zn) by atomic absorption in different brain areas of stressed rats. To do so, we investigated the effect of acute immobilization stress (single 1-hour session) on the distribution … …Neuroscience International, Vol. 3, Issue 2 · 14 Sep 2012 · 7,277 accessesView PDFCite
Research ArticleOpen accessIn the abstractModulation of the GABAA Receptor by Srif in Rat ThalamusFatiha Chigr, Mariama El Ouahli, Ghizlane Er-Raoui et al.Somatostatin has been reported to modulate GABAA receptor complex in many brain structures. This study was conducted to investigate somatostatin modulation of the GABAA receptor binding in several rat diencephalic structures, focusing primarily on the thalamus, as this structure plays important roles. Animals were assigned to control conditions. Changes in specific binding of GABAA receptor as labelled with [35S]t-Butylbicyclophosphorothionate (TBPS) … …Neuroscience International, Vol. 3, Issue 2 · 14 Sep 2012 · 6,963 accessesView PDFCite
Research ArticleOpen accessIn the abstractInverse Discrete Fourier Transform-Discrete Fourier Transform Techniques for Generating and Receiving Spectrally Efficient Frequency Division Multiplexing SignalsSahmed IdarwazehProblem statement: Spectrally Efficient Frequency Division Multiplexing (SEFDM) system promises bandwidth savings by multiplexing overlapped non-orthogonal sub-carriers. However, the loss of orthogonality results in increasing the complexity of generation and detection of the signal. In this work, we propose simple framework for the generation of the SEFDM signal based on the Inverse Discrete Fourier Transform (IDFT). Approach: This study further … …American Journal of Engineering and Applied Sciences, Vol. 4, Issue 4 · 31 Jul 2012 · 8,310 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Triune Brain: Limbic Mind Mind Plastic, Emotional MindFelice Corona, Francesco Perrotta, Carla CozzarelliProblem statement: The theory discussed is revealing, as compared to studies on the human brain, the fact that he has inherited the structure and organization of three fundamental types of reptiles, ancient or primitive mammals and mammals, or recent evolved. What is very disconcerting is that nature has been able to connect with each other and establish a sort of … …Current Research in Medicine, Vol. 2, Issue 1 · 15 Aug 2011 · 8,354 accessesView PDFCite
Research ArticleOpen accessIn the abstractOn-Chip Implementation of Pipeline Digit-Slicing Multiplier-Less Butterfly for Fast Fourier Transform ArchitectureYazan Samir Algnabi, Rozita Teymourzadeh, Masuri Othman et al.Problem statement: The need for wireless communication has driven the communication systems to high performance. However, the main bottleneck that affects the communication capability is the Fast Fourier Transform (FFT), which is the core of most modulators. Approach: This study presented on-chip implementation of pipeline digit-slicing multiplier-less butterfly for FFT structure. The approach taken; in order to reduce computation complexity … …American Journal of Engineering and Applied Sciences, Vol. 3, Issue 4 · 30 Nov 2010 · 8,010 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunodeficiency Provides Partial Protection from Bone Loss Induced by Castration and OvariectomyCedo M. Bagi, Edwin Berryman, Nels Hanson et al.Problem Statement: The interaction of osteoblasts and osteoclasts with cells of the immune system has been suggested as a contributing factor in the development of osteoporoses. Evidence from studies in rodents suggests that T cells play a significant role in bone loss following estrogen deficiency. The goal of this study was to investigate whether the lack of functional T cells … …Current Research in Medicine, Vol. 1, Issue 1 · 30 Jun 2010 · 7,074 accessesView PDFCite
Research ArticleOpen accessIn the abstractCryptolepine Provokes Changes in the Expression of Cell Cycle Proteins in Growing CellsCharles Ansah, Nigel J. GooderhamProblem statement: Cryptolepine, the antimalarial plant alkaloid is cytotoxic to mammalian cells, but there is rather little understanding of the possible mechanisms involved in the cell-kill action of cryptolepine. Approach: We examined mammalian cells exposed to cryptolepine (0.5-5.0 μM) for effects on the cell cycle and associated alterations in the levels of major regulatory proteins using immunoblotting and flow cytometry. … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 4 · 31 Dec 2009 · 7,396 accessesView PDFCite