Review ArticleOpen accessIn the abstractMicroRNA-92a: The Administrator of Certain DiseasesZhiyuan Sun, Qing Xu, Xiaoyi Tian et al.MicroRNA-92a (miR-92a) is an evolutionarily conserved noncoding small RNA that can regulate gene expression after transcription. Previous studies have found that miR-92a is overexpressed in many tumors and can regulate numerous tumor suppressor genes negatively, with relevant effects on the development of different tumors, by regulating the DUSP10/c-Jun N-terminal kinase (JNK), phosphatase and tensin homologs (PTEN)/AKT, Wnt and EP4/Notch1 signaling … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 21 May 2020 · 6,494 accessesView PDFCite
Research ArticleOpen accessIn the abstractImpact of Acute Bronchiolitis on Cardiac Functions and Serum microRNA-122 and 499Mona Abd El-Gelel Mohamed, Khalid Mahmoud ZayedBronchiolitis is an acute inflammatory injury of the bronchioles that is usually caused by a viral infection, most commonly Respiratory Syncytial Virus (RSV). This study aimed to verify the direct injurious effect of acute bronchiolitis on the myocardium and serum level of microRNA-122 and 499 (miR-122 and miR-499) of infected infants. Serum lactate dehydrogenase (LDH), creatine phosphokinase-isoenzyme MB (CK-MB) and … …American Journal of Infectious Diseases, Vol. 12, Issue 1 · 26 Jan 2016 · 7,250 accessesView PDFCite
Research ArticleOpen accessIn the abstractPrevalence of miRNAs in Introns and Cis-Regulatory Regions of Genes of the Somatotropic Axis in MammalsTatiana Shkurat, Dmitry Romanov, Evgeny Pshenichnyy et al.To understand the role of microRNA in genetic control of animal growth mechanisms, we performed bioinformatic analysis of the localization of microRNAs in introns and cis-regulatory regions of the somatotropic axis genes-GH1, GHRH, SST and IGF1 in Homo sapiens, Macaca mulatta, Pan troglodytes, Pongo abelii, Gorilla gorilla, Ovis aries, Bos Taurus, Loxodonta Africana, Oryctolagus cuniculus, Canis lupus, Rattus norvegicus and … …American Journal of Applied Sciences, Vol. 12, Issue 1 · 26 Jan 2015 · 7,015 accessesView PDFCite